46 research outputs found
A new occurrence of a classic "Árpád-type" mollusc fauna from the Upper Miocene of Kozármisleny, southern Hungary
A classic but very rare “Árpád-type”mollusc assemblage, representing the endemic fauna of the Late Miocene–Early
Pliocene Lake Pannon, was discovered in Kozármisleny (near Pécs, southern Hungary). The fossils were collected
from silt layers deposited in the shallow sublittoral zone of Lake Pannon, exposed in an 8–10 m high road cut. The
assemblage contained some very rare species, including the type species of the genus Lymnocardium, L. haueri (M.
HÖRNES). Palynological investigations from the same layers failed to yield age-diagnostic dinofl agellates, and
pointed to a brackish – freshwater depositional environment and warm temperate climate
Impact of aging on calcium influx and potassium channel characteristics of T lymphocytes.
Adaptive immunity and T cell function are affected by aging. Calcium influx patterns, regulated by Kv1.3 and IKCa1 potassium channels, influence T cell activation. We aimed to compare calcium influx kinetics in CD8, Th1 and Th2 cells in human peripheral blood samples obtained from five different age groups (cord blood, 10-15 ys, 25-40 ys, 45-55 ys, 60-75 ys).We measured calcium influx using flow cytometry in samples treated with or without specific inhibitors of Kv1.3 and IKCa1 channels (MGTX and TRAM, respectively).Calcium influx was higher in Th1 cells of adults, however, its extent decreased again with aging. Importantly, these changes were not detected in Th2 cells, where the pattern of calcium influx kinetics is similar throughout all investigated age groups. MGTX had a more pronounced inhibitory effect on calcium influx in Th2 cells, while in Th1 cells the same was true for TRAM in the 25-40 ys and 45-55 ys groups. Calcium influx of CD8 cells were inhibited to a similar extent by both applied inhibitors in these groups, and had no effect in the elderly.Altered lymphocyte potassium channel inhibitory patterns, regulators of calcium influx kinetics, might contribute to the development of age-related changes of T cell function
Magyar Gyógypedagógiai Tanárok Közlönye 04 (1942) 04
A Magyar Gyógypedagógiai Tanárok Országos Egyesületének hivatalos lapja és szakfolyóirata 4. (44.) évfolyam, 4. szám, Budapest, 1942. Előzménye: a "Siketnémák és Vakok Oktatásügye a Siketnémák és Vakok Tanárai Országos Egyesületének hivatalos lapja" című folyóirat, valamint beolvadt a "Magyar Gyógypedagógia a Magyar Gyógypedagógiai Társaság folyóirata"
Magyar Gyógypedagógiai Tanárok Közlönye 06 (1944) 05
A Magyar Gyógypedagógiai Tanárok Országos Egyesületének hivatalos lapja és szakfolyóirata 6. (46.) évfolyam, 5. szám, Budapest, 1944. Előzménye: a "Siketnémák és Vakok Oktatásügye a Siketnémák és Vakok Tanárai Országos Egyesületének hivatalos lapja" című folyóirat, valamint beolvadt a "Magyar Gyógypedagógia a Magyar Gyógypedagógiai Társaság folyóirata"