Light Water Reactor Sustainability Program Technical Basis Guide Describing How to Perform Safety Margin Configuration Risk Management

The INL has carried out a demonstration of the RISMC approach for the purpose of configuration risk management. We have shown how improved accuracy and realism can be achieved by simulating changes in risk – as a function of different configurations – in order to determine safety margins as the plant is modified. We described the various technical issues that play a role in these configuration-based calculations with the intent that future applications can take advantage of the analysis benefits while avoiding some of the technical pitfalls that are found for these types of calculations. Specific recommendations have been provided on a variety of topics aimed at improving the safety margin analysis and strengthening the technical basis behind the analysis process

Power-sharing in Africa's war zones: how important is the local level?

Research on power-sharing in Africa remains silent on the effects of national peace agreements on the sub-national level. Conversely, most armed conflicts originate and are fought in (or over) specific areas. A plausible hypothesis would be that for power-sharing to have the desired pacifying effect throughout the national territory, it needs to be extended to the local level. Based on fieldwork in six former hotspots in Liberia, Burundi and the Democratic Republic of Congo (DRC) we find that there is hardly any local content, including local power-sharing, in national agreements. However, contrary to our hypothesis, neither local content (inclusion of actors or interest) nor local-power-sharing (either introducing a local power balance or monopoly) are indispensable to effectively bring about local peace, at least in the short-term. On the contrary, it might even endanger the peace process. The importance of the sub-national level is overestimated in some cases and romanticised in others. However, the history of spatial-political links, centralised policies, and the establishment of local balances or monopolies of power ultimately play an important role

Social tipping points and Earth systems dynamics

Recently, Early Warning Signals (EWS) have been developed to predict tipping points in Earth Systems. This discussion highlights the potential to apply EWS to human social and economic systems, which may also undergo similar critical transitions. Social tipping points are particularly difficult to predict, however, and the current formulation of EWS, based on a physical system analogy, may be insufficient. As an alternative set of EWS for social systems, we join with other authors encouraging a focus on heterogeneity, connectivity through social networks and individual thresholds to change

Swift: primary data analysis for the Illumina Solexa sequencing platform

Motivation: Primary data analysis methods are of critical importance in second generation DNA sequencing. Improved methods have the potential to increase yield and reduce the error rates. Openly documented analysis tools enable the user to understand the primary data, this is important for the optimization and validity of their scientific work