MOSFET dosimetry for radiotherapy interface measurements

An n-channel Metal Oxide Semiconductor Field Effect Transistor (MOSFET) was used to investigate the dose distribution near interfaces

カソクキ オ モチイタ 7Li p n 7Be ハンノウ ノ シキイチ キンボウ チュウセイシ ノ ホウソ チュウセイシ ホソク リョウホウヨウ ショウシャ システム ノ ヒョウカ : チリョウ プロトコール ニ ヨル チリョウフカサ オ シヒョウ ニ シタ チュウセイシ ショウシャバ ノ トクセイ ヒョウカ

京都大学0048新制・課程博士博士(工学)甲第13055号工博第2797号新制||工||1406(附属図書館)UT51-2007-H328京都大学大学院工学研究科原子核工学専攻(主査)教授 丸橋 晃, 教授 伊藤 秋男, 助教授 古林 徹学位規則第4条第1項該当Doctor of EngineeringKyoto UniversityDA

A feasibility study of a molecular-based patient setup verification method using a parallel-plane PET system

A feasibility study of a novel PET-based molecular image guided radiation therapy (m-IGRT) system was conducted by comparing PET-based registration with radiographic registration. We selected a pair of opposing parallel-plane PET systems for the practical implementation. Five different sizes of 18F cylindrical sources (diameter: 8, 12, 16, 24, 32 mm) were used to determine setup errors. PET data acquisition times were 1, 3 and 5 min. Image registration was performed by 5 observers. Setup errors from the PET system were compared with setup errors from image intensifier-based fluoroscopy. The in-plane and cross-plane FWHM of the profile of a 2 mm diameter sources for the parallel-plane PET system were approximately 1.8 mm and 8.1 mm, respectively. The majority of the mean registration errors obtained from the PET-based registration were not significantly different from those obtained from the radiographic registration. Acquisition time did not appear to result in significant differences in the mean registration error. The mean registration error for the PET-based registration was found to be 0.93±0.33 mm. This is not statistically different from the radiographic registration which had mean registration error of 0.92±0.27 mm. Our results suggest that m-IGRT is feasible for clinical use with a parallel plane PET-based registration

A New Brain Positron Emission Tomography Scanner with Semiconductor Detectors for Target Volume Delineation and Radiotherapy Treatment Planning in Patients with Nasopharyngeal Carcinoma.

Two treatment planning methods for nasopharyngeal carcinoma were compared: conventional whole-body BGO scintillator positron emission tomography and a new brain PET system using semiconductor detec- tors. The average absolute volume of GTV contoured with the use of the new brain PET system was significantly smaller than that of conven- tional whole-body BGO PET. The new brain PET system using semiconductor detectors can provide more accurate tumor delineatio