1,108 research outputs found

    A WIMP Detector with Two-Phase Liquid Xenon

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    We describe the liquid-xenon dark-matter detector program of the UCLA-Torino team. A two-phase detector, ZEPLIN II, for the Boulby Mine is a good match for the current search for WIMP dark matter.Comment: 3 pages with 4 figures; for Proceedings, Sixth Int'l Wksp. On Topics in Astroparticle and Underground Physics, TAUP99 (College de France, Paris, Sept. 6-10, 1999), to be published in Nucl. Phys. B(PS

    Regulating the effects of GPR21, a novel target for type 2 diabetes

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    Type 2 diabetes is a chronic metabolic disorder primarily caused by insulin resistance to which obesity is a major contributor. Expression levels of an orphan G protein-coupled receptor (GPCR), GPR21, demonstrated a trend towards a significant increase in the epididymal fat pads of wild type high fat high sugar (HFHS)-fed mice. To gain further insight into the potential role this novel target may play in the development of obesity-associated type 2 diabetes, the signalling capabilities of the receptor were investigated. Overexpression studies in HEK293T cells revealed GPR21 to be a constitutively active receptor, which couples to Gα(q) type G proteins leading to the activation of mitogen activated protein kinases (MAPKs). Overexpression of GPR21 in vitro also markedly attenuated insulin signalling. Interestingly, the effect of GPR21 on the MAPKs and insulin signalling was reduced in the presence of serum, inferring the possibility of a native inhibitory ligand. Homology modelling and ligand docking studies led to the identification of a novel compound that inhibited GPR21 activity. Its effects offer potential as an anti-diabetic pharmacological strategy as it was found to counteract the influence of GPR21 on the insulin signalling pathway

    Photometric Identification of Type Ia Supernovae at Moderate Redshift

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    Large photometric surveys with the aim of identifying many Type Ia supernovae (SNe) at moderate redshift are challenged in separating these SNe from other SN types. We are motivated to identify Type Ia SNe based only on broadband photometric information, since spectroscopic determination of the SN type, the traditional method, requires significant amounts of time on large telescopes. We consider the possible observables provided by a large synoptic photometry survey. We examine the optical colors and magnitudes of many SN types from z=0.1 to z=1.0, using space-based ultraviolet spectra and ground-based optical spectra to simulate the photometry. We also discuss the evolution of colors over the SN outburst and the use of host galaxy characteristics to aid in the identification of Type Ia SNe. We consider magnitudes in both the SDSS photometric system and in a proposed filter system with logarithmically spaced bandpasses. We find that photometric information in four bands covering the entire optical spectrum appears capable of providing identification of Type Ia SNe based on their colors at a single observed epoch soon after maximum light, even without independent estimates of the SN redshift. Very blue filters are extremely helpful, as at moderate redshift they sample the restframe ultraviolet spectrum where the SN types are very different. We emphasize the need for further observations of SNe in the restframe ultraviolet to fully characterize, refine, and improve this method of SN type identification.Comment: AASTeX, 37 pages with 12 figures, being resubmitted to A.J. Figures 3, 4 and 9 updated, minor typos correcte

    First operation of a liquid Argon TPC embedded in a magnetic field

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    We have operated for the first time a liquid Argon TPC immersed in a magnetic field up to 0.55 T. We show that the imaging properties of the detector are not affected by the presence of the magnetic field. The magnetic bending of the ionizing particle allows to discriminate their charge and estimate their momentum. These figures were up to now not accessible in the non-magnetized liquid Argon TPC.Comment: 9 pages, 3 figure

    Signatures of an eruptive phase before the explosion of the peculiar core-collapse SN 2013gc

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    We present photometric and spectroscopic analysis of the peculiar core-collapse SN 2013gc, spanning seven years of observations. The light curve shows an early maximum followed by a fast decline and a phase of almost constant luminosity. At +200 days from maximum, a brightening of 1 mag is observed in all bands, followed by a steep linear luminosity decline after +300 d. In archival images taken between 1.5 and 2.5 years before the explosion, a weak source is visible at the supernova location, with mag\approx20. The early supernova spectra show Balmer lines, with a narrow (\sim560 km s1^{-1}) P-Cygni absorption superimposed on a broad (\sim3400 km s1^{-1}) component, typical of type IIn events. Through a comparison of colour curves, absolute light curves and spectra of SN 2013gc with a sample of supernovae IIn, we conclude that SN 2013gc is a member of the so-called type IId subgroup. The complex profile of the Hα\alpha line suggests a composite circumstellar medium geometry, with a combination of lower velocity, spherically symmetric gas and a more rapidly expanding bilobed feature. This circumstellar medium distribution has been likely formed through major mass-loss events, that we directly observed from 3 years before the explosion. The modest luminosity (MI16.5M_I\sim-16.5 near maximum) of SN 2013gc at all phases, the very small amount of ejected 56^{56}Ni (of the order of 10310^{-3} M_\odot), the major pre-supernova stellar activity and the lack of prominent [O I] lines in late-time spectra support a fall-back core-collapse scenario for the massive progenitor of SN~2013gc.Comment: 20 pages, 11 figures, 8 tables, accepted by MNRA

    A Study of the Residual 39Ar Content in Argon from Underground Sources

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    The discovery of argon from underground sources with significantly less 39Ar than atmospheric argon was an important step in the development of direct-detection dark matter experiments using argon as the active target. We report on the design and operation of a low background detector with a single phase liquid argon target that was built to study the 39Ar content of the underground argon. Underground argon from the Kinder Morgan CO2 plant in Cortez, Colorado was determined to have less than 0.65% of the 39Ar activity in atmospheric argon.Comment: 21 pages, 10 figure

    The early spectral evolution of SN 2004dt

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    Aims. We study the optical spectroscopic properties of Type Ia Supernova (SN Ia) 2004dt, focusing our attention on the early epochs. Methods. Observation triggered soon after the SN 2004dt discovery allowed us to obtain a spectrophotometric coverage from day -10 to almost one year (~353 days) after the B band maximum. Observations carried out on an almost daily basis allowed us a good sampling of the fast spectroscopic evolution of SN 2004dt in the early stages. To obtain this result, low-resolution, long-slit spectroscopy was obtained using a number of facilities. Results. This supernova, which in some absorption lines of its early spectra showed the highest degree of polarization ever measured in any SN Ia, has a complex velocity structure in the outer layers of its ejecta. Unburnt oxygen is present, moving at velocities as high as ~16,700 km/s, with some intermediate-mass elements (Mg, Si, Ca) moving equally fast. Modeling of the spectra based on standard density profiles of the ejecta fails to reproduce the observed features, whereas enhancing the density of outer layers significantly improves the fit. Our analysis indicates the presence of clumps of high-velocity, intermediate-mass elements in the outermost layers, which is also suggested by the spectropolarimetric data.Comment: 13 pages, 15 figures, accepted for pubblication in Astronomy and Astrophysic
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