Government Books for Winter Reading

Bibliography and photographs of a display of government documents from St. John\u27s University/College of St. Benedict, Minnesota.https://cornerstone.lib.mnsu.edu/lib-services-govdoc-display-govdocs/1014/thumbnail.jp

Mathematical foundations for a compositional account of the Bayesian brain

This dissertation reports some first steps towards a compositional account of active inference and the Bayesian brain. Specifically, we use the tools of contemporary applied category theory to supply functorial semantics for approximate inference. To do so, we define on the 'syntactic' side the new notion of Bayesian lens and show that Bayesian updating composes according to the compositional lens pattern. Using Bayesian lenses, and inspired by compositional game theory, we define fibrations of statistical games and classify various problems of statistical inference as corresponding sections: the chain rule of the relative entropy is formalized as a strict section, while maximum likelihood estimation and the free energy give lax sections. In the process, we introduce a new notion of 'copy-composition'. On the 'semantic' side, we present a new formalization of general open dynamical systems (particularly: deterministic, stochastic, and random; and discrete- and continuous-time) as certain coalgebras of polynomial functors, which we show collect into monoidal opindexed categories (or, alternatively, into algebras for multicategories of generalized polynomial functors). We use these opindexed categories to define monoidal bicategories of 'cilia': dynamical systems which control lenses, and which supply the target for our functorial semantics. Accordingly, we construct functors which explain the bidirectional compositional structure of predictive coding neural circuits under the free energy principle, thereby giving a formal mathematical underpinning to the bidirectionality observed in the cortex. Along the way, we explain how to compose rate-coded neural circuits using an algebra for a multicategory of linear circuit diagrams, showing subsequently that this is subsumed by lenses and polynomial functors. Because category theory is unfamiliar to many computational neuroscientists and cognitive scientists, we have made a particular effort to give clear, detailed, and approachable expositions of all the category-theoretic structures and results of which we make use. We hope that this dissertation will prove helpful in establishing a new "well-typed'' science of life and mind, and in facilitating interdisciplinary communication

What\u27s Cookin\u27? in Parkston, S.D.

Recipes contributed by Sister Amata -- Hors d\u27oeuvres, pickles, relishes -- Soups, salads, vegetables -- Meat, fish, poultry -- Bread, rolls, pastry -- Cakes, cookies -- Desserts -- Candy, jelly, preserves -- Beverages and miscellaneous -- Weight control.https://openprairie.sdstate.edu/sd_cookbooks/1067/thumbnail.jp

MEASURING WORKPLACE RELATIONSHIP AND JOB SATISFACTION OF DIVINE WORD COLLEGES' EMPLOYEES IN ILOCOS REGION

The study wants to determine the relationship between workplace relationship and job satisfactionInternational audienceThe study was conducted to determine workplace relationship between employer and employees and among employees of Divine Word Colleges inIlocosRegion, Philippines and satisfaction. Literatures and studies were reviewed, and questionnaires were used to gather the data related to workplace relationship and job satisfaction. The respondents of the study are employees of the Divine Word Colleges of Ilo descriptive study involving survey and fact to determine the workplace relationship and its correlation with job satisfaction. The s there is a significant correlation between workplace relationship and job satisfaction. Therefore, the study recommends that management need to monitor and improve workplace relationship between employer and employees and among employees an satisfaction

Identification of D-arabinan-degrading enzymes in mycobacteria

Bacterial cell growth and division require the coordinated action of enzymes that synthesize and degrade cell wall polymers. Here, we identify enzymes that cleave the D-arabinan core of arabinogalactan, an unusual component of the cell wall of Mycobacterium tuberculosis and other mycobacteria. We screened 14 human gut-derived Bacteroidetes for arabinogalactan-degrading activities and identified four families of glycoside hydrolases with activity against the D-arabinan or D-galactan components of arabinogalactan. Using one of these isolates with exo-D-galactofuranosidase activity, we generated enriched D-arabinan and used it to identify a strain of Dysgonomonas gadei as a D-arabinan degrader. This enabled the discovery of endo- and exo-acting enzymes that cleave D-arabinan, including members of the DUF2961 family (GH172) and a family of glycoside hydrolases (DUF4185/GH183) that display endo-D-arabinofuranase activity and are conserved in mycobacteria and other microbes. Mycobacterial genomes encode two conserved endo-D-arabinanases with different preferences for the D-arabinan-containing cell wall components arabinogalactan and lipoarabinomannan, suggesting they are important for cell wall modification and/or degradation. The discovery of these enzymes will support future studies into the structure and function of the mycobacterial cell wall

Q Factor in cycling: kinematic and physiological effects

Q Factor represents the horizontal distance between pedals on a bicycle, measured from the outside edge of each crankarm. The action of pedalling is based upon human gait, which utilises a step width lower than standard Q Factors (150mm for road bicycles). The aims of this thesis were to understand the kinematic and physiological effects of manipulating Q Factor. Lower Q Factors than standard afforded increased gross mechanical efficiency and individually determined optimal Q Factor (OQ) provided increased power output during laboratory time trials. Self selected Q Factor (SSQ) was lower than standard in trained cyclists and could be predicted using a simple suspension task. The use of SSQ compared with Q Factors higher and lower than SSQ provided a combination of kinematic stability and increased efficiency, lowering the risk of injury and the oxygen cost of cycling. Lower Q Factors than the standard 150mm for road bicycles provide performance and kinematic benefits that have not been examined previously. As part of the overall package of bicycle fit, individual cyclists will be able to make measurable improvements by finding and utilising their self selected Q Factor

The effects of partial sleep restriction and altered sleep timing on appetite and food reward.

We examined the effects of partial sleep restriction (PSR) with an advanced wake-time or delayed bedtime on measures of appetite, food reward and subsequent energy intake (EI). Twelve men and 6 women (age: 23 ± 4 years, body fat: 18.8 ± 10.1%) participated in 3 randomized crossover sessions: control (habitual bed- and wake-time), 50% PSR with an advanced wake-time and 50% PSR with a delayed bedtime. Outcome variables included sleep architecture (polysomnography), ad libitum EI (validated food menu), appetite sensations (visual analogue scales), the satiety quotient (SQ; mm/100 kcal) and food reward (Leeds Food Preference Questionnaire and the relative-reinforcing value (RRV) of preferred food task). Increased fasting and post-standard breakfast appetite ratings were noted following PSR with an advanced wake-time compared to the control and PSR with a delayed bedtime sessions (Fasting hunger ratings: 77 ± 16 vs. 65 ± 18 and 64 ± 16; P = 0.01; Post-meal hunger AUC: 5982 ± 1781 vs. 4508 ± 2136 and 5198 ± 2201; P = 0.03). Increased explicit wanting and liking for high-relative to low-fat foods were also noted during the advanced wake-time vs. control session (Explicit wanting: -3.5 ± 12.5 vs. -9.3 ± 8.9, P = 0.01; Explicit liking: -1.6 ± 8.5 vs. -7.8 ± 9.6, P = 0.002). No differences in the RRV of preferred food, the SQ and ad libitum lunch intake were noted between sessions. These findings suggest that appetite sensations and food reward are increased following PSR with an advanced wake-time, rather than delayed bedtime, vs. CONTROL: However, this did not translate into increased EI during a test meal. Given the increasing prevalence of shift workers and incidences of sleep disorders, additional studies are needed to evaluate the prolonged effects of voluntary sleep restriction with altered sleep timing on appetite and EI measurements

The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth

\ua9 The Author(s) 2024.Mycobacterial glycolipids are important cell envelope structures that drive host-pathogen interactions. Arguably, the most important are lipoarabinomannan (LAM) and its precursor, lipomannan (LM), which are trafficked from the bacterium to the host via unknown mechanisms. Arabinomannan is thought to be a capsular derivative of these molecules, lacking a lipid anchor. However, the mechanism by which this material is generated has yet to be elucidated. Here, we describe the identification of a glycoside hydrolase family 76 enzyme that we term LamH (Rv0365c in Mycobacterium tuberculosis) which specifically cleaves α−1,6-mannoside linkages within LM and LAM, driving its export to the capsule releasing its phosphatidyl-myo-inositol mannoside lipid anchor. Unexpectedly, we found that the catalytic activity of this enzyme is important for efficient exit from stationary phase cultures, potentially implicating arabinomannan as a signal for growth phase transition. Finally, we demonstrate that LamH is important for M. tuberculosis survival in macrophages