DEXTRAN SULFATE STABILIZED SILVER NANOPARTICLE: NEXT GENERATION EFFICIENT THERAPY FOR CANCER

Objective: Synthesize silver nanoparticles using a green synthesis approach and encapsulate silver nanoparticles with a naturally occurring polymer, particularly of an-hydroglucose type, like dextran sulfate sodium salt and to study its anticancer activity. Methods: Green synthesis approach is been employed in the synthesis of silver nanoparticles using Psidium guajava leaf extract. The nanoparticles were then encapsulated with dextran sulfate biopolymer and the nanoparticles were subjected to different characterization techniques. The structure of the synthesized nanoparticles was analyzed using X-ray diffraction analysis, the presence of different functional groups was analyzed by FTIR studies. Size and morphology of the prepared nanoparticles were investigated using FESEM analysis. Anticancer activity of the synthesized nanoparticles was tested against the MCF-cell line. Results: The XRD analysis shows the crystalline nature of the synthesized nanoparticles. The stretching and vibrating modes of different functional groups were confirmed by FTIR result. The SEM image confirmed the presence of spherical shaped nanoparticles and the TEM image confirmed the average size of the particles to be around 24 nm. The Ag-DS NPs showed 91% cell inhibition for the concentration of 100 μg/ml, indicating the cytotoxicity of the nanoparticles against MCF-7 cell line. Conclusion: Dextran sulfate stabilized silver nanoparticles show potent anticancer activity against MCF-7 cell line

Synthesis and Characterization of Magnesium Doped Ferric Sulphate Nanoparticles (Mg-Fe2SO3 NPs) for Agriculture Applications

The present study aimed to synthesize the magnesium doped ferric sulphate nanoparticles (Mg-Fe2SO3 NPs) and investigate their seed germination efficacy. Mg-Fe2SO3 NPs were prepared by a simple and cost-effective method and subjected to characterization. The X-ray Diffraction (XRD) spectrum revealed the crystalline nature of Mg-Fe2SO3 NPs with an average crystallite size of 36.41 nm. The field emission scanning electron microscope (FESEM) image displayed the agglomeration of Mg-Fe2SO3 NPs with the shape of the grains appeared like starfish which has limbs grown from a common cluster. The energy dispersive X-ray spectroscopy (EDS) demonstrated the existence of C (10.5%), O (49.14%), Fe (26.67%), Mg (0.78%) and S (13.35%) elements in Mg-Fe2SO3 NPs. It also revealed the absence of impurities in the synthesized NPs. Through Fourier transform infrared spectroscopy (FTIR), Mg-Fe2SO3 NPs showed the characteristic peaks at 615.29cm-1, 1130.29cm-1, 1400.32 cm-1and 1633.71cm-1 which corresponded to Fe-O, C-N, O-H and N-H vibration respectively. Further, the seed germination study revealed that the Mg-Fe2SO3 NPs treatment caused a significant increase in seedling growth of cowpea (Vigna unguiculata) seeds compared to the untreated samples

Fabrication of dye sensitized solar cells using BaTiO3 blocking layer

Dye-sensitized solar cells (DSSCs) have great potential for solar generation due to their low cost and simplicity of fabrication compared with silicon-based photovoltaic devices. One of the major problems with TiO2-based DSSCs is the recombination loss at the substrate–electrolyte interface due to the mesoporous nature of the TiO2 film. It was proposed earlier that introduction of a blocking layer at the substrate–TiO2 interface could reduce this recombination loss by preventing direct contact of the substrate and electrolyte. In this present work, Barium titanate (BaTiO3) nanoparticles prepared by using wet chemical method. The prepared nanoparticles were thermally evaporated on to well cleaned fluorine-doped tin oxide (FTO) glass under the vacuum of 2 x10-5 torr at different thickness and used as electron-blocking layer of dye-sensitized solar cell (DSSC). The BaTiO3 blocking layer functions as an energy barrier at the FTO–electrolyte interface to prevent back transfer of electrons to the electrolyte from the FTO. The blocking effect of the BaTiO3 blocking layer was verified by an enhancement of the fill factor (FF) and open-circuit photovoltage (Voc) of the DSSC, leading to an improvement in the power conversion efficiency (PCE) from 3.86% to 4.34% for the BaTiO3 blocking layer with optimum thickness of 80 nm. The TiO2 layers were printed on top BaTiO3 to assemble for a dye sensitized solar cells. DSSCs with the structure of FTO/BaTiO3/TiO2/Dye/EL/Pt/FTO have been prepared, and their solar-cell performance was evaluated.

Thickness dependence on structural, dielectric and AC conduction studies of vacuum evaporated Sr doped BaTiO3 thin films

Barium titanate (BaTiO3) doped with Strontium (BST) nanoparticles prepared by using wet chemical method were thermally evaporated on to well cleaned glass substrates under the vacuum of 2 × 10−5 Torr, using 12A4 Hind Hivac coating unit. The thickness of the film was measured by quartz crystal monitor. From X-ray analysis, it has been found that BaTiO3 nanoparticles possess tetragonal structure and deposited films has a polycrystalline in nature, whereas the crystallinity of film increases with increase of temperature. Surface morphology of the prepared thin film was found to be uniform. The transport mechanism in these films under a.c. fields was studied in the frequency range 12 Hz to 100 kHz, at different temperatures (303–483 K). The dependence of dielectric constant and loss factor for different thickness was investigated and results are discussed. The process of a.c. conduction has been explained on the basis of hopping conduction mechanism. The dielectric constant (ɛ′), temperature co-efficient of capacitance (TCC) and temperature co-efficient of permitivity (TCP) were estimated. The dependence of activation energy on thickness also studied and reported

Thickness and Annealing Effects on Thermally Evaporated InZnO Thin Films for Gas Sensors and Blue, Green and Yellow Emissive Optical Devices

Indium zinc oxide (InZnO) thin films with thicknesses of 100 nm and 200 nm were deposited on glass plate by thermal evaporation technique. Fourier transform infrared spectra showed a strong metal-oxide bond. X-ray diffraction patterns revealed amorphous nature for as-deposited film whereas polycrystalline structure for annealed films. Scanning electron microscope images showed a uniform distribution of spherical shape grains. Grain size was found to be higher for 200 nm film than 100 nm film. The presence of elements (In, Zn and O) was confirmed from energy dispersive X-ray analysis. Photoluminescence study of 200 nm film showed a blue, blue-green and blue-yellow emission whereas 100 nm film showed a broad green and green-yellow emissions. Both 100 nm and 200 nm films showed good oxygen sensitivity from room temperature to 400 °C. The observed optical and sensor results indicated that the prepared InZnO films are highly potential for room temperature gas sensor and blue, green and yellow emissive opto-electronic device

Thickness dependence on structural, dielectric and AC conduction studies of vacuum evaporated Sr doped BaTiO3 thin films

Barium titanate (BaTiO3) doped with Strontium (BST) nanoparticles prepared by using wet chemical method were thermally evaporated on to well cleaned glass substrates under the vacuum of 2 × 10−5 Torr, using 12A4 Hind Hivac coating unit. The thickness of the film was measured by quartz crystal monitor. From X-ray analysis, it has been found that BaTiO3 nanoparticles possess tetragonal structure and deposited films has a polycrystalline in nature, whereas the crystallinity of film increases with increase of temperature. Surface morphology of the prepared thin film was found to be uniform. The transport mechanism in these films under a.c. fields was studied in the frequency range 12 Hz to 100 kHz, at different temperatures (303–483 K). The dependence of dielectric constant and loss factor for different thickness was investigated and results are discussed. The process of a.c. conduction has been explained on the basis of hopping conduction mechanism. The dielectric constant (ɛ′), temperature co-efficient of capacitance (TCC) and temperature co-efficient of permitivity (TCP) were estimated. The dependence of activation energy on thickness also studied and reported