1,511 research outputs found
Reducing Urban Pollution Exposure from Road Transport(RUPERT)
This paper presents the preliminary results of a two-year study on reducing urban pollution exposure from road transport (RUPERT). The main aim of this project
is to develop a new modelling framework for nitrogen dioxide, carbon monoxide and particulate matter to simulate exposures of different population groups
across a city, and to assess the impact of roadside concentrations on these exposures. This will be achieved by modelling the frequency distribution of
personal exposures (PEFDs) as a function of urban background and roadside concentrations, under different traffic conditions. The modelling approach combines new and existing models relating traffic and air pollution data, with particular emphasis of the impact of congestion, and the probabilistic modelling framework of personal exposure. Modelling of roadside concentrations consists of two main elements, namely the analysis of concentrations patterns at different roadside sites and of the relationship between traffic conditions and added
roadside pollution. Roadside concentrations are predicted using empirically derived relationships; statistical models, novel statistics and artificial neural
networks namely feed forward neural network and radial basis neural network. The exposure modelling is carried out by linking two models: the INDAIR model, which is designed to simulate probabilistically diurnal profiles of air pollutant concentrations in a range of microenvironments, and the EXPAIR model, which is designed to simulate population exposure patterns based on
population time-activity patterns and a library of micro-environmental concentrations derived from the INDAIR model
Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3
INTRODUCTION:
Involution of the mammary gland is a complex process of controlled apoptosis and tissue remodelling. The aim of the project was to identify genes that are specifically involved in this process.
METHODS:
We used Affymetrix oligonucleotide microarrays to perform a detailed transcript analysis on the mechanism of controlled involution after withdrawal of the pups at day seven of lactation. Some of the results were confirmed by semi-quantitative reverse transcriptase polymerase chain reaction, Western blotting or immunohistochemistry.
RESULTS:
We identified 145 genes that were specifically upregulated during the first 4 days of involution; of these, 49 encoded immunoglobulin genes. A further 12 genes, including those encoding the signal transducer and activator of transcription 3 (STAT3), the lipopolysaccharide receptor (CD14) and lipopolysaccharide-binding protein (LBP), were involved in the acute-phase response, demonstrating that the expression of acute-phase response genes can occur in the mammary gland itself and not only in the liver. Expression of LBP and CD14 was upregulated, at both the RNA and protein level, immediately after pup withdrawal; CD14 was strongly expressed in the luminal epithelial cells. Other genes identified suggested neutrophil activation early in involution, followed by macrophage activation late in the process. Immunohistochemistry and histological staining confirmed the infiltration of the involuting mammary tissue with neutrophils, plasma cells, macrophages and eosinophils.
CONCLUSION:
Oligonucleotide microarrays are a useful tool for identifying genes that are involved in the complex developmental process of mammary gland involution. The genes identified are consistent with an immune cascade, with an early acute-phase response that occurs in the mammary gland itself and resembles a wound healing process
Experimental Implementation of Projective Measurement in Bell Basis
A scheme for direct projection of a quantum state on Bell states is
described. The method is based on constructing an average Hamiltonian with Bell
eigenstates and then, projecting the state on these eigenstates. The projection
is performed by adding the results of a direct and time-reversed evolution.
Experimental demonstration is shown for pairs of dipolar-coupled nuclear spins.Comment: 10 pages, 3 figures, submitte
Engineering Entanglement between two cavity modes
We present scheme for generation of entanglement between different modes of
radiation field inside high-Q superconducting cavities. Our scheme is based on
the interaction of a three-level atom with the cavity field for pre-calculated
interaction times with each mode. This work enables us to generate complete set
of Bell basis states and GHZ state
A measurable entanglement criterion for two qubits
We propose a directly measurable criterion for the entanglement of two
qubits. We compare the criterion with other criteria, and we find that for pure
states, and some mixed states, it coincides with the state's concurrency. The
measure can be obtained with a Bell state analyser and the ability to make
general local unitary transformations. However, the procedure fails to measure
the entanglement of a general mixed two-qubit state.Comment: 5 page
Efficient quantum key distribution scheme with nonmaximally entangled states
We propose an efficient quantum key distribution scheme based on
entanglement. The sender chooses pairs of photons in one of the two equivalent
nonmaximally entangled states randomly, and sends a sequence of photons from
each pair to the receiver. They choose from the various bases independently but
with substantially different probabilities, thus reducing the fraction of
discarded data, and a significant gain in efficiency is achieved. We then show
that such a refined data analysis guarantees the security of our scheme against
a biased eavesdropping strategy.Comment: 5 Pages, No Figur
Entangled graphs: Bipartite entanglement in multi-qubit systems
Quantum entanglement in multipartite systems cannot be shared freely. In
order to illuminate basic rules of entanglement sharing between qubits we
introduce a concept of an entangled structure (graph) such that each qubit of a
multipartite system is associated with a point (vertex) while a bi-partite
entanglement between two specific qubits is represented by a connection (edge)
between these points. We prove that any such entangled structure can be
associated with a pure state of a multi-qubit system. Moreover, we show that a
pure state corresponding to a given entangled structure is a superposition of
vectors from a subspace of the -dimensional Hilbert space, whose dimension
grows linearly with the number of entangled pairs.Comment: 6 revtex pages, 2 figures, to appear in Phys. Rev.
State-independent quantum violation of noncontextuality in four dimensional space using five observables and two settings
Recently, a striking experimental demonstration [G. Kirchmair \emph{et al.},
Nature, \textbf{460}, 494(2009)] of the state-independent quantum mechanical
violation of non-contextual realist models has been reported for any two-qubit
state using suitable choices of \emph{nine} product observables and \emph{six}
different measurement setups. In this report, a considerable simplification of
such a demonstration is achieved by formulating a scheme that requires only
\emph{five} product observables and \emph{two} different measurement setups. It
is also pointed out that the relevant empirical data already available in the
experiment by Kirchmair \emph{et al.} corroborate the violation of the NCR
models in accordance with our proof
A high-flux source of polarization-entangled photons from a periodically-poled KTP parametric downconverter
We have demonstrated a high-flux source of polarization-entangled photons
using a type-II phase-matched periodically-poled KTP parametric downconverter
in a collinearly propagating configuration. We have observed quantum
interference between the single-beam downconverted photons with a visibility of
99% and a measured coincidence flux of 300/s/mW of pump. The
Clauser-Horne-Shimony-Holt version of Bell's inequality was violated with a
value of 2.711 +/- 0.017.Comment: 7 pages submitted to Physical Review
One-Way Entangled-Photon Autocompensating Quantum Cryptography
A new quantum cryptography implementation is presented that combines one-way
operation with an autocompensating feature that has hitherto only been
available in implementations that require the signal to make a round trip
between the users. Using the concept of advanced waves, it is shown that this
new implementation is related to the round-trip implementations in the same way
that Ekert's two-particle scheme is related to the original one-particle scheme
of Bennett and Brassard. The practical advantages and disadvantages of the
proposed implementation are discussed in the context of existing schemes.Comment: 5 pages, 1 figure; Minor edits--conclusions unchanged; accepted for
publication in Physical Review
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