514 research outputs found
Templates for Convex Cone Problems with Applications to Sparse Signal Recovery
This paper develops a general framework for solving a variety of convex cone
problems that frequently arise in signal processing, machine learning,
statistics, and other fields. The approach works as follows: first, determine a
conic formulation of the problem; second, determine its dual; third, apply
smoothing; and fourth, solve using an optimal first-order method. A merit of
this approach is its flexibility: for example, all compressed sensing problems
can be solved via this approach. These include models with objective
functionals such as the total-variation norm, ||Wx||_1 where W is arbitrary, or
a combination thereof. In addition, the paper also introduces a number of
technical contributions such as a novel continuation scheme, a novel approach
for controlling the step size, and some new results showing that the smooth and
unsmoothed problems are sometimes formally equivalent. Combined with our
framework, these lead to novel, stable and computationally efficient
algorithms. For instance, our general implementation is competitive with
state-of-the-art methods for solving intensively studied problems such as the
LASSO. Further, numerical experiments show that one can solve the Dantzig
selector problem, for which no efficient large-scale solvers exist, in a few
hundred iterations. Finally, the paper is accompanied with a software release.
This software is not a single, monolithic solver; rather, it is a suite of
programs and routines designed to serve as building blocks for constructing
complete algorithms.Comment: The TFOCS software is available at http://tfocs.stanford.edu This
version has updated reference
Implantação e Padronização dos Serviços de Atenção Farmacêutica no Programa de Automonitoramento Glicêmico Capilar da Universidade do Extremo Sul Catarinense
A atenção farmacêutica é um processo assistencial que ocorre por meio da interação direta do farmacêutico com o paciente para atender suas necessidades relacionadas aos medicamentos, visando uma farmacoterapia racional e a obtenção de resultados definidos e mensuráveis, cooperando, assim, para a melhoria da qualidade de vida do paciente
Alterations to nuclear architecture and genome behavior in senescent cells.
The organization of the genome within interphase nuclei, and how it interacts with nuclear structures is important for the regulation of nuclear functions. Many of the studies researching the importance of genome organization and nuclear structure are performed in young, proliferating, and often transformed cells. These studies do not reveal anything about the nucleus or genome in nonproliferating cells, which may be relevant for the regulation of both proliferation and replicative senescence. Here, we provide an overview of what is known about the genome and nuclear structure in senescent cells. We review the evidence that nuclear structures, such as the nuclear lamina, nucleoli, the nuclear matrix, nuclear bodies (such as promyelocytic leukemia bodies), and nuclear morphology all become altered within growth-arrested or senescent cells. Specific alterations to the genome in senescent cells, as compared to young proliferating cells, are described, including aneuploidy, chromatin modifications, chromosome positioning, relocation of heterochromatin, and changes to telomeres
Thermodynamics of pyrope-majorite, Mg3Al2Si3O12-Mg4Si4O12, solid solution from atomistic model calculations
Static lattice energy calculations, based on empirical pair potentials have been performed for a large set of different structures with compositions between pyrope and majorite, and with different states of order of octahedral cations. The energies have been cluster expanded using pair and quaternary terms. The derived ordering constants have been used to constrain Monte Carlo simulations of temperature-dependent properties in the ranges of 1073 3673K and 0 20 GPa. The free energies of mixing have been calculated using the method of thermodynamic integration. At zero pressure the cubic/tetragonal transition is predicted for pure majorite at 3300 K. The transition temperature decreases with the increase of the pyrope mole fraction. A miscibility gap associated with the transition starts to develop at about 2000K and xmaj 0.8, and widens with the decrease in temperature and the increase in pressure. Activity composition relations in the range of 0 20 GPa and 1073 2673K are described with the help of a high-order Redlich Kister polynomial
High-time Resolution Astrophysics and Pulsars
The discovery of pulsars in 1968 heralded an era where the temporal
characteristics of detectors had to be reassessed. Up to this point detector
integration times would normally be measured in minutes rather seconds and
definitely not on sub-second time scales. At the start of the 21st century
pulsar observations are still pushing the limits of detector telescope
capabilities. Flux variations on times scales less than 1 nsec have been
observed during giant radio pulses. Pulsar studies over the next 10 to 20 years
will require instruments with time resolutions down to microseconds and below,
high-quantum quantum efficiency, reasonable energy resolution and sensitive to
circular and linear polarisation of stochastic signals. This chapter is review
of temporally resolved optical observations of pulsars. It concludes with
estimates of the observability of pulsars with both existing telescopes and
into the ELT era.Comment: Review; 21 pages, 5 figures, 86 references. Book chapter to appear
in: D.Phelan, O.Ryan & A.Shearer, eds.: High Time Resolution Astrophysics
(Astrophysics and Space Science Library, Springer, 2007). The original
publication will be available at http://www.springerlink.co
Measurement of W Polarisation at LEP
The three different helicity states of W bosons produced in the reaction e+
e- -> W+ W- -> l nu q q~ at LEP are studied using leptonic and hadronic W
decays. Data at centre-of-mass energies \sqrt s = 183-209 GeV are used to
measure the polarisation of W bosons, and its dependence on the W boson
production angle. The fraction of longitudinally polarised W bosons is measured
to be 0.218 \pm 0.027 \pm 0.016 where the first uncertainty is statistical and
the second systematic, in agreement with the Standard Model expectation
Search for Anomalous Couplings in the Higgs Sector at LEP
Anomalous couplings of the Higgs boson are searched for through the processes
e^+ e^- -> H gamma, e^+ e^- -> e^+ e^- H and e^+ e^- -> HZ. The mass range 70
GeV < m_H < 190 GeV is explored using 602 pb^-1 of integrated luminosity
collected with the L3 detector at LEP at centre-of-mass energies
sqrt(s)=189-209 GeV. The Higgs decay channels H -> ffbar, H -> gamma gamma, H
-> Z\gamma and H -> WW^(*) are considered and no evidence is found for
anomalous Higgs production or decay. Limits on the anomalous couplings d, db,
Delta(g1z), Delta(kappa_gamma) and xi^2 are derived as well as limits on the H
-> gamma gamma and H -> Z gamma decay rates
Measurement of W Polarisation at LEP
The three different helicity states of W bosons produced in the reaction e+
e- -> W+ W- -> l nu q q~ at LEP are studied using leptonic and hadronic W
decays. Data at centre-of-mass energies \sqrt s = 183-209 GeV are used to
measure the polarisation of W bosons, and its dependence on the W boson
production angle. The fraction of longitudinally polarised W bosons is measured
to be 0.218 \pm 0.027 \pm 0.016 where the first uncertainty is statistical and
the second systematic, in agreement with the Standard Model expectation
Bose-Einstein Correlations of Neutral and Charged Pions in Hadronic Z Decays
Bose-Einstein correlations of both neutral and like-sign charged pion pairs
are measured in a sample of 2 million hadronic Z decays collected with the L3
detector at LEP. The analysis is performed in the four-momentum difference
range 300 MeV < Q < 2 GeV. The radius of the neutral pion source is found to be
smaller than that of charged pions. This result is in qualitative agreement
with the string fragmentation model
Z Boson Pair-Production at LEP
Events stemming from the pair-production of Z bosons in e^+e^- collisions are
studied using 217.4 pb^-1 of data collected with the L3 detector at
centre-of-mass energies from 200 GeV up to 209 GeV. The special case of events
with b quarks is also investigated.
Combining these events with those collected at lower centre-of-mass energies,
the Standard Model predictions for the production mechanism are verified. In
addition, limits are set on anomalous couplings of neutral gauge bosons and on
effects of extra space dimensions
- …