586 research outputs found

    Personalentwicklung von Nachwuchswissenschaftlern. Eine empirische Studie bei Habilitanden des Fachs "Betriebswirtschaftslehre"

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    Becker FG, Schröder C. Personalentwicklung von Nachwuchswissenschaftlern. Eine empirische Studie bei Habilitanden des Fachs "Betriebswirtschaftslehre". Diskussionspapier der FakultĂ€t fĂŒr Wirtschaftswissenschaften / UniversitĂ€t Bielefeld. Vol 504. Bielefeld: UniversitĂ€t Bielefeld, FakultĂ€t fĂŒr Wirtschaftswissenschaften; 2003

    Mutations affecting ligand specificity of the G-protein-coupled receptor for the Saccharomyces cerevisiae tridecapeptide pheromone

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    AbstractRandom mutations were generated in the G-protein-coupled receptor (Ste2p) for the tridecapeptide pheromone (α-factor) of Saccharomyces cerevisiae. These mutants were screened for variants that responded to antagonists. Because multiple mutations were detected in each mutant receptor recovered from the screen, site-directed mutagenesis was used to create single-site mutant receptors. Three receptors containing mutations F55V, S219P, and S259P were analyzed for their biological responses to various α-factor analogs and for their ligand binding profiles. Cells expressing each of the mutant receptors responded to α-factor as well as or better than wild-type cells in a growth arrest assay. In contrast, the binding of α-factor to the F55V and S219P mutant receptors was at least 10-fold reduced in comparison to wild-type receptor indicating a complex non-linear correlation between binding affinity and biological activity. Cells expressing mutant receptors responded to some normally inactive analogs in biological assays, despite the fact that these analogs had a low affinity for Ste2p. The analysis of these mutant receptors confirms previous findings that the first and sixth transmembrane regions of Ste2p are important for ligand interaction, ligand specificity, and/or receptor activation to initiate the signal transduction pathway. Changes in binding affinity of pheromone analogs to wild-type and mutant receptors indicate that residue 55 of Ste2p is involved with both ligand binding and signal transduction

    Potential Melting of Extrasolar Planets by Tidal Dissipation

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    Tidal heating on Io due to its finite eccentricity was predicted to drive surface volcanic activity, which was subsequently confirmed by the Voyager\textit{Voyager} spacecrafts. Although the volcanic activity in Io is more complex, in theory volcanism can be driven by runaway melting in which the tidal heating increases as the mantle thickness decreases. We show that this runaway melting mechanism is generic for a composite planetary body with liquid core and solid mantle, provided that (i) the mantle rigidity, ÎŒ\mu, is comparable to the central pressure, i.e. ÎŒ/(ρgRP)≳0.1\mu/ (\rho g R_{\rm P})\gtrsim0.1 for a body with density ρ\rho, surface gravitational acceleration gg, and radius RPR_{\rm P}, (ii) the surface is not molten, (iii) tides deposit sufficient energy, and (iv) the planet has nonzero eccentricity. We calculate the approximate liquid core radius as a function of ÎŒ/(ρgRP)\mu/ (\rho g R_{\rm P}), and find that more than 90%90\% of the core will melt due to this runaway for ÎŒ/(ρgRP)≳1\mu/ (\rho g R_{\rm P})\gtrsim1. From all currently confirmed exoplanets, we find that the terrestrial planets in the L98-59 system are the most promising candidates for sustaining active volcanism. However, uncertainties regarding the quality factors and the details of tidal heating and cooling mechanisms prohibit definitive claims of volcanism on any of these planets. We generate synthetic transmission spectra of these planets assuming Venus-like atmospheric compositions with an additional 5, 50, and 98%98\% SO2_2 component, which is a tracer of volcanic activity. We find a ≳3σ\gtrsim 3 \sigma preference for a model with SO2_2 with 5-10 transits with JWST\textit{JWST} for L98-59bcd.Comment: 16 pages, 8 Figures, accepted for publication in Ap

    Evidence for Color Dichotomy in the Primordial Neptunian Trojan Population

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    In the current model of early Solar System evolution, the stable members of the Jovian and Neptunian Trojan populations were captured into resonance from the leftover reservoir of planetesimals during the outward migration of the giant planets. As a result, both Jovian and Neptunian Trojans share a common origin with the primordial disk population, whose other surviving members constitute today's trans-Neptunian object (TNO) populations. The cold classical TNOs are ultra-red, while the dynamically excited "hot" population of TNOs contains a mixture of ultra-red and blue objects. In contrast, Jovian and Neptunian Trojans are observed to be blue. While the absence of ultra-red Jovian Trojans can be readily explained by the sublimation of volatile material from their surfaces due to the high flux of solar radiation at 5AU, the lack of ultra-red Neptunian Trojans presents both a puzzle and a challenge to formation models. In this work we report the discovery by the Dark Energy Survey (DES) of two new dynamically stable L4 Neptunian Trojans,2013 VX30 and 2014 UU240, both with inclinations i >30 degrees, making them the highest-inclination known stable Neptunian Trojans. We have measured the colors of these and three other dynamically stable Neptunian Trojans previously observed by DES, and find that 2013 VX30 is ultra-red, the first such Neptunian Trojan in its class. As such, 2013 VX30 may be a "missing link" between the Trojan and TNO populations. Using a simulation of the DES TNO detection efficiency, we find that there are 162 +/- 73 Trojans with Hr < 10 at the L4 Lagrange point of Neptune. Moreover, the blue-to-red Neptunian Trojan population ratio should be higher than 17:1. Based on this result, we discuss the possible origin of the ultra-red Neptunian Trojan population and its implications for the formation history of Neptunian Trojans

    A Compact Multi-Planet System With A Significantly Misaligned Ultra Short Period Planet

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    We report the discovery of a compact multi-planet system orbiting the relatively nearby (78pc) and bright (K=8.9K=8.9) K-star, K2-266 (EPIC248435473). We identify up to six possible planets orbiting K2-266 with estimated periods of Pb_b = 0.66, P.02_{.02} = 6.1, Pc_c = 7.8, Pd_d = 14.7, Pe_e = 19.5, and P.06_{.06} = 56.7 days and radii of RP_P = 3.3 R⊕_{\oplus}, 0.646 R⊕_{\oplus}, 0.705 R⊕_{\oplus}, 2.93 R⊕_{\oplus}, 2.73 R⊕_{\oplus}, and 0.90 R⊕_{\oplus}, respectively. We are able to confirm the planetary nature of two of these planets (d & e) from analyzing their transit timing variations (md=8.9−3.8+5.7M⊕m_d= 8.9_{-3.8}^{+5.7} M_\oplus and me=14.3−5.0+6.4M⊕m_e=14.3_{-5.0}^{+6.4} M_\oplus), confidently validate the planetary nature of two other planets (b & c), and classify the last two as planetary candidates (K2-266.02 & .06). From a simultaneous fit of all 6 possible planets, we find that K2-266 b's orbit has an inclination of 75.32∘^{\circ} while the other five planets have inclinations of 87-90∘^{\circ}. This observed mutual misalignment may indicate that K2-266 b formed differently from the other planets in the system. The brightness of the host star and the relatively large size of the sub-Neptune sized planets d and e make them well-suited for atmospheric characterization efforts with facilities like the Hubble Space Telescope and upcoming James Webb Space Telescope. We also identify an 8.5-day transiting planet candidate orbiting EPIC248435395, a co-moving companion to K2-266.Comment: 18 pages, 12 figures, 7 tables, Accepted for Publication in the Astronomical Journa

    LSST: from Science Drivers to Reference Design and Anticipated Data Products

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    (Abridged) We describe here the most ambitious survey currently planned in the optical, the Large Synoptic Survey Telescope (LSST). A vast array of science will be enabled by a single wide-deep-fast sky survey, and LSST will have unique survey capability in the faint time domain. The LSST design is driven by four main science themes: probing dark energy and dark matter, taking an inventory of the Solar System, exploring the transient optical sky, and mapping the Milky Way. LSST will be a wide-field ground-based system sited at Cerro Pach\'{o}n in northern Chile. The telescope will have an 8.4 m (6.5 m effective) primary mirror, a 9.6 deg2^2 field of view, and a 3.2 Gigapixel camera. The standard observing sequence will consist of pairs of 15-second exposures in a given field, with two such visits in each pointing in a given night. With these repeats, the LSST system is capable of imaging about 10,000 square degrees of sky in a single filter in three nights. The typical 5σ\sigma point-source depth in a single visit in rr will be ∌24.5\sim 24.5 (AB). The project is in the construction phase and will begin regular survey operations by 2022. The survey area will be contained within 30,000 deg2^2 with ÎŽ<+34.5∘\delta<+34.5^\circ, and will be imaged multiple times in six bands, ugrizyugrizy, covering the wavelength range 320--1050 nm. About 90\% of the observing time will be devoted to a deep-wide-fast survey mode which will uniformly observe a 18,000 deg2^2 region about 800 times (summed over all six bands) during the anticipated 10 years of operations, and yield a coadded map to r∌27.5r\sim27.5. The remaining 10\% of the observing time will be allocated to projects such as a Very Deep and Fast time domain survey. The goal is to make LSST data products, including a relational database of about 32 trillion observations of 40 billion objects, available to the public and scientists around the world.Comment: 57 pages, 32 color figures, version with high-resolution figures available from https://www.lsst.org/overvie

    Measurement of the cosmic ray spectrum above 4×10184{\times}10^{18} eV using inclined events detected with the Pierre Auger Observatory

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    A measurement of the cosmic-ray spectrum for energies exceeding 4×10184{\times}10^{18} eV is presented, which is based on the analysis of showers with zenith angles greater than 60∘60^{\circ} detected with the Pierre Auger Observatory between 1 January 2004 and 31 December 2013. The measured spectrum confirms a flux suppression at the highest energies. Above 5.3×10185.3{\times}10^{18} eV, the "ankle", the flux can be described by a power law E−γE^{-\gamma} with index Îł=2.70±0.02 (stat)±0.1 (sys)\gamma=2.70 \pm 0.02 \,\text{(stat)} \pm 0.1\,\text{(sys)} followed by a smooth suppression region. For the energy (EsE_\text{s}) at which the spectral flux has fallen to one-half of its extrapolated value in the absence of suppression, we find Es=(5.12±0.25 (stat)−1.2+1.0 (sys))×1019E_\text{s}=(5.12\pm0.25\,\text{(stat)}^{+1.0}_{-1.2}\,\text{(sys)}){\times}10^{19} eV.Comment: Replaced with published version. Added journal reference and DO

    Energy Estimation of Cosmic Rays with the Engineering Radio Array of the Pierre Auger Observatory

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    The Auger Engineering Radio Array (AERA) is part of the Pierre Auger Observatory and is used to detect the radio emission of cosmic-ray air showers. These observations are compared to the data of the surface detector stations of the Observatory, which provide well-calibrated information on the cosmic-ray energies and arrival directions. The response of the radio stations in the 30 to 80 MHz regime has been thoroughly calibrated to enable the reconstruction of the incoming electric field. For the latter, the energy deposit per area is determined from the radio pulses at each observer position and is interpolated using a two-dimensional function that takes into account signal asymmetries due to interference between the geomagnetic and charge-excess emission components. The spatial integral over the signal distribution gives a direct measurement of the energy transferred from the primary cosmic ray into radio emission in the AERA frequency range. We measure 15.8 MeV of radiation energy for a 1 EeV air shower arriving perpendicularly to the geomagnetic field. This radiation energy -- corrected for geometrical effects -- is used as a cosmic-ray energy estimator. Performing an absolute energy calibration against the surface-detector information, we observe that this radio-energy estimator scales quadratically with the cosmic-ray energy as expected for coherent emission. We find an energy resolution of the radio reconstruction of 22% for the data set and 17% for a high-quality subset containing only events with at least five radio stations with signal.Comment: Replaced with published version. Added journal reference and DO
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