Effect of Resveratrol on Hematological and Biochemical Alterations in Rats Exposed to Fluoride

We investigated the protective effects of resveratrol on hematological and biochemical changes induced by fluoride in rats. A total of 28 rats were divided into 4 groups: control, resveratrol, fluoride, and fluoride/resveratrol ( = 7 each), for a total of 21 days of treatment. Blood samples were taken and hematological and biochemical parameters were measured. Compared to the control group, the fluoride-treated group showed significant differences in several hematological parameters, including decreases in WBC, RBC, and PLT counts and neutrophil ratio. The group that received resveratrol alone showed a decrease in WBC count compared to the control group. Furthermore, in comparison to the control group, the fluoride group showed significantly increased ALT enzyme activity and decreased inorganic phosphorus level. The hematological and biochemical parameters in the fluoride + resveratrol treated group were similar to control group. In the fluoride + resveratrol group, resveratrol restored the changes observed following fluoride treatment, including decreased counts of WBC, RBC, and PLT, decreased neutrophil ratio and inorganic phosphorus levels, and elevated ALT enzyme activity. The present study showed that fluoride caused adverse effects in rats and that resveratrol reduced hematological and biochemical alterations produced by fluoride exposure

Effect of Resveratrol on Hematological and Biochemical Alterations in Rats Exposed to Fluoride

We investigated the protective effects of resveratrol on hematological and biochemical changes induced by fluoride in rats. A total of 28 rats were divided into 4 groups: control, resveratrol, fluoride, and fluoride/resveratrol ( = 7 each), for a total of 21 days of treatment. Blood samples were taken and hematological and biochemical parameters were measured. Compared to the control group, the fluoride-treated group showed significant differences in several hematological parameters, including decreases in WBC, RBC, and PLT counts and neutrophil ratio. The group that received resveratrol alone showed a decrease in WBC count compared to the control group. Furthermore, in comparison to the control group, the fluoride group showed significantly increased ALT enzyme activity and decreased inorganic phosphorus level. The hematological and biochemical parameters in the fluoride + resveratrol treated group were similar to control group. In the fluoride + resveratrol group, resveratrol restored the changes observed following fluoride treatment, including decreased counts of WBC, RBC, and PLT, decreased neutrophil ratio and inorganic phosphorus levels, and elevated ALT enzyme activity. The present study showed that fluoride caused adverse effects in rats and that resveratrol reduced hematological and biochemical alterations produced by fluoride exposure

Structure of the quail (Coturnix coturnix japonica) spleen during pre-and post-hatching periods

The structure of the quail spleen at late embryonic stages and during the post-hatching period was determined by light microscopy using different staining techniques. Whereas the spleen growth was limited compared to the body growth in embryonic stages. the relative spleen weight increased 2.8 fold during the first 4 weeks post-hatching in quail. At 10 days of egg incubation, erythropoiesis was predominant. but on the 11(th) day. granulocyte islets were formed around vessels and the ellipsoids appeared around the penicilliform capillary on the 12(th) day. The capsule of Schweigger-Seidel sheath (CSSS) wrapped them on the 15(th) day and although they were not well defined, the pen-arterial lymphatic sheath (PALS) and the peri-ellipsoidal white pulp (PWP) appeared on the 16(th) day. At hatching, the granulocyte islets disappeared and the white pulp was gradually colonized with lymphocytes according to the age. In parallel, the thickness of the CSSS increased, especially after the 10(th) day post-hatching. In 30 day old quails. the PALS mainly consisted of small lymphocytes. The number of lymphocytes was superior in the PALS areas than in the PWP in 60 days old quails. Plasma cells were found in the PWP and especially in the red pulp around pulp veins during the post-hatching period. In conclusion, the quail spleen undergoes structural changes throughout the pre- and post-hatching periods

LOMBER DİSK HASTALARINDA AŞIRI AKTİF MESANE SENDROMUNUN DEĞERLENDİRİLMESİ

RESULT : There may be urological problems in patients with lumbar disc hernia at differentiating degrees. These problems, as well giving rise to medical problems, may also lead to social challenges. The clinician, while questioning the pain, motor and sensory deficit in terms of lumbar disc hernia, should also take into consideration the urological problems indicating close/frequent association at a considerable amoun