4 research outputs found
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Re/Writing the Orient: Ludovico Ariosto’s Orlando Furioso, the Thousand and One Nights, and the Hundred and One Nights
Canto XXIII marks a tragicomic turning point in the Orlando Furioso, as the tension sustaining the titular character’s epic stoicism and romantic chivalry falls away to reveal a maniacal anti-hero. This canto’s staging of Orlando’s madness signals a significant extra-textual literary transition, unsettling the binary of medieval and classical literary traditions that Ariosto draws on, and suggesting a novel genre of literary expression. This article explores one avenue by which Ariosto disrupts such ostensible polarities through the dynamic intertextual practice of writing and rewriting the “Orient.”  A close reading of Canto XXVIII’s resounding echoes of the Thousand and One Nights’ and the lesser-known Hundred and One Nights’ frame tales, illuminates the Furioso’s double focus upon movement toward and away from Muslim-Arab cultural affiliation, a push-pull that opens a space of difference where literary traditions can converge neither in reconciliation nor domination of one another. In particular, this paper examines how Ariosto’s poem captures the ambiguous hybridity of the medieval Mediterranean as an ever-shifting terrain defined not only by oppositionality and hostility, but also by curiosity, exchange, and alliance
Recommended from our members
Re/Writing the Orient: Ludovico Ariosto’s Orlando Furioso, the Thousand and One Nights, and the Hundred and One Nights
Canto XXIII marks a tragicomic turning point in the Orlando Furioso, as the tension sustaining the titular character’s epic stoicism and romantic chivalry falls away to reveal a maniacal anti-hero. This canto’s staging of Orlando’s madness signals a significant extra-textual literary transition, unsettling the binary of medieval and classical literary traditions that Ariosto draws on, and suggesting a novel genre of literary expression. This article explores one avenue by which Ariosto disrupts such ostensible polarities through the dynamic intertextual practice of writing and rewriting the “Orient.”  A close reading of Canto XXVIII’s resounding echoes of the Thousand and One Nights’ and the lesser-known Hundred and One Nights’ frame tales, illuminates the Furioso’s double focus upon movement toward and away from Muslim-Arab cultural affiliation, a push-pull that opens a space of difference where literary traditions can converge neither in reconciliation nor domination of one another. In particular, this paper examines how Ariosto’s poem captures the ambiguous hybridity of the medieval Mediterranean as an ever-shifting terrain defined not only by oppositionality and hostility, but also by curiosity, exchange, and alliance
Sex Differences in Translocator Protein 18Â kDa (TSPO) in the Heart: Implications for Imaging Myocardial Inflammation
Myocarditis is more severe in men than women and difficult to diagnose due to a lack of imaging modalities that directly detect myocardial inflammation. Translocator protein 18 kDa (TSPO) is used extensively to image brain inflammation due to its presence in CD11b(+) brain microglia. In this study we examined expression of TSPO and CD11b in mice with coxsackievirus B3 (CVB3) myocarditis and biopsy sections from myocarditis patients in order to determine if it could be used to image myocarditis. We found that male mice with CVB3 myocarditis upregulated more genes associated with TSPO activation than females. TSPO expression was increased in the heart of male mice and men with myocarditis compared to females due to testosterone, where it was expressed predominantly in CD11b(+) immune cells. We show that TSPO ligands detect myocardial inflammation using microSPECT, with increased uptake of [(125)I]-IodoDPA-713 in male mice with CVB3 myocarditis compared to undiseased controls