8 research outputs found
Observation of a quenched moment of inertia in a rotating strongly interacting Fermi gas
We make a model-independent measurement of the moment of inertia of a
rotating, expanding strongly-interacting Fermi gas. Quenching of the moment of
inertia is observed for energies both below and above the superfluid
transition. This shows that a strongly interacting Fermi gas with angular
momentum can support irrotational flow in both the superfluid and collisional
normal fluid regimes.Comment: 4 pages 5 figure
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Angular Mapping of Protein Structure Using Nonlinear Optical Measurements
Proteins are inherently dynamic, flexible molecules that execute precise conformational changes to perform their functions, but existing techniques to directly measure relevant structural changes in solution at room temperature remain limited. Here, we demonstrate a structural technique using second-harmonic generation and two-photon fluorescence under single-laser excitation to map both the mean angular orientation and the distribution width of a probe at various sites throughout the protein with high sensitivity. Our work resolves distinct dihydrofolate reductase (DHFR) ligand-protein conformations, allows interrogation of regions unresolvable by other techniques, and reveals structural differences between DHFR and a point mutant (DHFR-G121V). The technique, angular mapping of protein structure, enables direct and rapid determination of previously unseen aspects of protein structure in a benchtop optical system