The impact of iodine supplementation and bread fortification on urinary iodine concentrations in a mildly iodine deficient population of pregnant women in South Australia

Abstract Mild iodine deficiency during pregnancy can have significant effects on fetal development and future cognitive function. The purpose of this study was to characterise the iodine status of South Australian women during pregnancy and relate it to the use of iodine-containing multivitamins. The impact of fortification of bread with iodized salt was also assessed. Women (n = 196) were recruited prospectively at the beginning of pregnancy and urine collected at 12, 18, 30, 36 weeks gestation and 6 months postpartum. The use of a multivitamin supplement was recorded at each visit. Spot urinary iodine concentrations (UIC) were assessed. Median UICs were within the mildly deficient range in women not taking supplements (<90 μg/L). Among the women taking iodine-containing multivitamins UICs were within WHO recommendations (150-249 μg/L) for sufficiency and showed an increasing trend through gestation. The fortification of bread with iodized salt increased the median UIC from 68 μg/L to 84 μg/L (p = .011) which was still in the deficient range. Pregnant women in this region of Australia were unlikely to reach recommended iodine levels without an iodine supplement, even after the mandatory iodine supplementation of bread was instituted in October 2009

The impact of iodine supplementation and bread fortification on urinary iodine concentrations in a mildly iodine deficient population of pregnant women in South Australia

Mild iodine deficiency during pregnancy can have significant effects on fetal development and future cognitive function. The purpose of this study was to characterise the iodine status of South Australian women during pregnancy and relate it to the use of iodine-containing multivitamins. The impact of fortification of bread with iodized salt was also assessed. Women (n = 196) were recruited prospectively at the beginning of pregnancy and urine collected at 12, 18, 30, 36 weeks gestation and 6 months postpartum. The use of a multivitamin supplement was recorded at each visit. Spot urinary iodine concentrations (UIC) were assessed. Median UICs were within the mildly deficient range in women not taking supplements (<90 μg/L). Among the women taking iodine-containing multivitamins UICs were within WHO recommendations (150–249 μg/L) for sufficiency and showed an increasing trend through gestation. The fortification of bread with iodized salt increased the median UIC from 68 μg/L to 84 μg/L (p = .011) which was still in the deficient range. Pregnant women in this region of Australia were unlikely to reach recommended iodine levels without an iodine supplement, even after the mandatory iodine supplementation of bread was instituted in October 2009.Vicki L Clifton, Nicolette A Hodyl, Paul A Fogarty, David J Torpy, Rachel Roberts, Ted Nettelbeck, Gary Ma and Basil Hetze

The Elimination of Brain Damage due to Iodine Deficiency

This item is a document written by Basil Hetzel on Iodine Deficiency and the International Council for Control of Iodine Deficiency Disorders (ICCIDD)

Eliminating iodine deficiency disorders--the role of the International Council in the global partnership.

Iodine deficiency is the most common preventable cause of brain damage. WHO estimates that some 2.2 billion people are at risk from iodine deficiency in 130 countries. A programme of universal salt iodization was established in 1994 with the aim of eliminating the problem by 2000. This paper reports progress in this field, with particular reference to the primarily scientific role of the International Council for Control of Iodine Deficiency Disorders, a nongovernmental organization founded in 1986. It is now a multidisciplinary network of 600 professionals in 100 countries

Some applications of modern biochemistry in clinical medicine

Typewritten copyThesis (M.D.)--University of Adelaide, Dept. of Medicine, 194

Professor Basil Hetzel in interview with Dr Max Blythe: Part 1

Professor Basil Hetzel of the Royal Australasian College of Physicians talks of his family background in Europe and S. Australia, medical training in Adelaide and induction into medical research through interests in endocrinology, particularly the relationship between the adrenal cortex and thyroid and stress which led to important overseas attachments. Then, from a clinical research base in Adelaide he developed field interests in the distribution of goitre and goitrous cretinism in New Guinea, an interest leading to controlled trials of iodised oil injections in the highlands of Papua. In this interview he discusses the field findings and supporting laboratory research that validated prevention by iodised oil.Interest then turns to an appointment with Australia's CSIRO providing opportunities to monitor the influence of iodine deficiency states on embryonic brain development, work demonstrating the importance of both maternal and foetal thyroid metabolism. In a final part of the interview Professor Hetzel discusses his resulting international commitments to reducing vitamin deficiency disease incidence, including WHO and UNICEF initiatives

Access to iodized salt in 11 low- and lower-middle-income countries: 2000 and 2010

drawing, reconstr. ceremonial bldg w/out dome (ext); section w/ dome, 200

HYPERTHYROIDISM AND PREDNISONE

SCOPUS: le.jinfo:eu-repo/semantics/publishe