Psychological type preferences of Christian groups : comparison with the UK population norms

A sample of 246 male and 380 female participants in courses about psychological type theory in a Christian context completed Form G (Anglicised) of the Myers-Briggs Personality Type Indicator® (MBTI®) instrument. The male Christians demonstrated clear preferences for Introversion, Sensing, Thinking, and Judging. The female Christians demonstrated clear preferences for Introversion, Sensing, Feeling, and Judging. The predominant type among the men was ISTJ (18%) and the predominant type among the women was ISFJ (21%). The type preferences of the current samples were statistically compared with the United Kingdom population norms. The male Christians preferred Intuition and Judging significantly more frequently than the male UK population norms, and the female Christians preferred Introversion, Intuition, and Judging significantly more frequently than the female UK population norms

Cosmic-Ray Positrons: Are There Primary Sources?

Cosmic rays at the Earth include a secondary component originating in collisions of primary particles with the diffuse interstellar gas. The secondary cosmic rays are relatively rare but carry important information on the Galactic propagation of the primary particles. The secondary component includes a small fraction of antimatter particles, positrons and antiprotons. In addition, positrons and antiprotons may also come from unusual sources and possibly provide insight into new physics. For instance, the annihilation of heavy supersymmetric dark matter particles within the Galactic halo could lead to positrons or antiprotons with distinctive energy signatures. With the High-Energy Antimatter Telescope (HEAT) balloon-borne instrument, we have measured the abundances of positrons and electrons at energies between 1 and 50 GeV. The data suggest that indeed a small additional antimatter component may be present that cannot be explained by a purely secondary production mechanism. Here we describe the signature of the effect and discuss its possible origin.Comment: 15 pages, Latex, epsfig and aasms4 macros required, to appear in Astroparticle Physics (1999

Dominant mutations of the Notch ligand Jagged1 cause peripheral neuropathy

Notch signaling is a highly conserved intercellular pathway with tightly regulated and pleiotropic roles in normal tissue development and homeostasis. Dysregulated Notch signaling has also been implicated in human disease, including multiple forms of cancer, and represents an emerging therapeutic target. Successful development of such therapeutics requires a detailed understanding of potential on-target toxicities. Here, we identify autosomal dominant mutations of the canonical Notch ligand Jagged1 (or JAG1) as a cause of peripheral nerve disease in 2 unrelated families with the hereditary axonal neuropathy Charcot-Marie-Tooth disease type 2 (CMT2). Affected individuals in both families exhibited severe vocal fold paresis, a rare feature of peripheral nerve disease that can be life-threatening. Our studies of mutant protein posttranslational modification and localization indicated that the mutations (p.Ser577Arg, p.Ser650Pro) impair protein glycosylation and reduce JAG1 cell surface expression. Mice harboring heterozygous CMT2-associated mutations exhibited mild peripheral neuropathy, and homozygous expression resulted in embryonic lethality by midgestation. Together, our findings highlight a critical role for JAG1 in maintaining peripheral nerve integrity, particularly in the recurrent laryngeal nerve, and provide a basis for the evaluation of peripheral neuropathy as part of the clinical development of Notch pathway-modulating therapeutics.This article is freely available via Open Access. Click on the publisher URL to access it via the publisher's site.G1002279/MRC_/Medical Research Council/United Kingdom R25 NS065729/NS/NINDS NIH HHS/United States Z01 AG000949/ImNIH/Intramural NIH HHS/United States R01 NS062869/NS/NINDS NIH HHS/United States F31 NS105404/NS/NINDS NIH HHS/United Statespre-print, post-print, publisher's version/PD

Decolonising indigenous social impact research using community-based methods

© 2019 Association of Researchers in Construction Management, ARCOM 2019 - Proceedings of the 35th Annual Conference. All rights reserved. Indigenous procurement policies encourage the construction sector to provide new training, employment and business opportunities for Indigenous people suffering from economic and social disadvantage. However, the success of these policies is often distorted by the failure of policy evaluations to account for Indigenous perceptions of social value. Since these often differ markedly from non-Indigenous values, this can distort the allocation of funds to Indigenous communities and exacerbate the marginalisation of the communities these policies are meant to help. Drawing on theories of community-based research, this methodological paper seeks to reconceptualise approaches to measuring Indigenous social value in an Indigenous social procurement policy context. Working in partnership with a peak body for Aboriginal business in Australia, we have co-designed a novel approach to Indigenous social impact research that recognises the legitimacy of Indigenous perspectives when investigating the social value Indigenous procurement policies create. We argue that culturally appropriate focus groups (yarning discussion groups) are appropriate in Indigenous social impact research because they prioritise Indigenous people's experiences of Indigenous procurement policies, rather than focusing on simplistic policy targets. As a method that promotes community involvement in social impact research to define how social value is perceived, yarning discussion groups have significant implications for future research seeking to represent Indigeonus perspectives of social value. It is concluded the approach developed here can be operationalised in the field to better understand the nature of Indigenous social value and the impact created by Indigenous procurement policies in Australia and other countries with disadvantaged Indigenous populations

IceCube's In-Ice Radio Extension: Status and Results

In 2006-2010, several Radio Frequency (RF) detectors and calibration equipment were deployed as part of the IceCube array at depths between 5 to 1400 meters in preparation for a future large scale GZK neutrino detector. IceCube's deep holes and well-established data handling system provide a unique opportunity for deep-ice RF detection studies at the South-Pole. We will present verification and calibration results as well as a status-review of ongoing analyses such as ice-properties, RF noise and reconstruction algorithms.Comment: 4 pages, 6 figures, to appear in the proceedings of the Acoustic and Radio EeV Neutrino detection Activities (ARENA) 2010 conferenc

Design and implementation of a fs-resolved transmission electron microscope based on thermionic gun technology [post-print]

In this paper, the design and implementation of a femtosecond-resolved ultrafast transmission electron microscope is presented, based on a thermionic gun geometry. Utilizing an additional magnetic lens between the electron acceleration and the nominal condenser lens system, a larger percentage of the electrons created at the cathode are delivered to the specimen without degrading temporal, spatial and energy resolution significantly, while at the same time maintaining the femtosecond temporal resolution. Using the photon-induced near field electron microscopy effect (PINEM) on silver nanowires the cross-correlation between the light and electron pulses was measured, showing the impact of the gun settings and initiating laser pulse duration on the electron bunch properties. Tuneable electron pulses between 300 fs and several ps can be obtained, and an overall energy resolution around 1 eV was achieved

Imaging in myeloma with focus on advanced imaging techniques.

In recent years, there have been major advances in the imaging of myeloma with whole body MRI incorporating diffusion-weighted imaging, emerging as the most sensitive modality. Imaging is now a key component in the work-up of patients with a suspected diagnosis of myeloma. The International Myeloma Working Group now specifies that more than one focal lesion on MRI or lytic lesion on whole body low-dose CT or fludeoxyglucose (FDG) PET/CT fulfil the criteria for bone damage requiring therapy. The recent National Institute for Health and Care Excellence myeloma guidelines recommend imaging in all patients with suspected myeloma. In addition, there is emerging data supporting the use of functional imaging techniques (WB-DW MRI and FDG PET/CT) to predict outcome and evaluate response to therapy. This review summarises the imaging modalities used in myeloma, the latest guidelines relevant to imaging and future directions

An alternative construction of B-M and B-T unitals in Desarguesian planes

We present a new construction of non-classical unitals from a classical unital $U$ in $PG(2,q^2)$. The resulting non-classical unitals are B-M unitals. The idea is to find a non-standard model $\Pi$ of $PG(2,q^2)$ with the following three properties: 1. points of $\Pi$ are those of $PG(2,q^2)$; 2. lines of $\Pi$ are certain lines and conics of $PG(2,q^2)$; 3. the points in $U$ form a non-classical B-M unital in $\Pi$. Our construction also works for the B-T unital, provided that conics are replaced by certain algebraic curves of higher degree.Comment: Keywords: unital, desarguesian plane 11 pages; ISSN: 0012-365

AURA - A radio frequency extension to IceCube

The excellent radio frequency transparency of cold polar ice, combined with the coherent Cherenkov emission produced by neutrino-induced showers when viewed at wavelengths longer than a few centimeters, has spurred considerable interest in a large-scale radio-wave neutrino detector array. The AURA (Askaryan Under-ice Radio Array) experimental effort, within the IceCube collaboration, seeks to take advantage of the opportunity presented by IceCube drilling through 2010 to establish the radio frequency technology needed to achieve 100-1000 km^3 effective volumes. In the 2006-2007 Austral summer 3 deep in-ice radio frequency (RF) clusters were deployed at depths of 1300m and 300m on top of the IceCube strings. Additional 3 clusters will be deployed in the Austral summer of 2008-2009. Verification and calibration results from the current deployed clusters are presented, and the detector design and performances are discussed. Augmentation of IceCube with large-scale 1000km^3sr radio and acoustic arrays would extend the physics reach of IceCube into the EeV-ZeV regime and offer substantial technological redundancy.Comment: To appear in the proceedings of the Acoustic and Radio EeV Neutrino detection Activities (ARENA) 2008 conferenc