26,590 research outputs found
A knowledge creation perspective on ‘LEAN’ approaches to policing in England and Wales
The police service in England and Wales continue to face intense pressures to manage and reduce budgets while simultaneously maintaining and improving levels of service. In achieving reform, attention has been directed towards the implementation of proven operational improvement frameworks, such as ‘lean thinking’ taken from the automotive industry. However, the qualitatively different contexts have resulted in ‘lean’ interventions making only limited contribution to police reform. This research draws on contemporary views of ‘lean’ as a knowledge creation process to assess how such a reconceptualization may contribute to more successful police transformation
Do the citizens of Europe trust their police?
Purpose - The maintenance of public order and the control of crime are clearly amongst the primary objectives of global law enforcement agencies. An important antecedent to this is the consideration of public trust in their police force. The purpose of this paper is to utilise data from the 5th Round European Social Survey (ESS), to investigate how public social indicators may highlight the level of trust in a country’s police force. Design/methodology/approach – The results from the ESS are analysed using fuzzy-set Qualitative Comparative Analysis (fsQCA), multiply conjunctional causal configurations of the considered social indicators are then established and analysed. Findings - A consequence of using fsQCA, asymmetric causal configurations are identified for the relative high and low limiting levels of trust towards the police in the considered countries. The results offer novel insights into the relationship between social indicators and police trust, as well as expositing a nascent technique (fsQCA) that may offer future potential in this area. Originality/value – This paper introduces a novel technique to analyse a major European data set relating to citizens perceptions of the police. The findings might prove useful for policing organisations as they develop strategies to maintain/improve the level of trust and confidence of citizens in the policing services they provide
Two-phase flow patterns in turbulent flow through a dose diffusion pipe
A numerical investigation is carried out for turbulent particle-laden flow through a dose diffusion pipe for a model reactor system. A Lagrangian Stochastic Monte-Carlo particle-tracking approach and the averaged Reynolds equations with a k-e turbulence model, with a two-layer zonal method in the boundary layer, are used for the disperse and continuous phases. The flow patterns coupled with the particle dynamics are predicted. It is observed that the coupling of the continuous phase with the particle dynamics is important in this case. It was found that the geometry of the throat significantly influences the particle distribution, flow patterns and length of the recirculation region. The accuracy of the simulations depends on the numerical prediction and correction of the fluid phase velocity during a characteristic time interval of the particles. A numerical solution strategy for the computation of two-way momentum coupled flow is discussed. The three test cases show different flow features in the formation of a recirculation region behind the throat. The method will be useful for the qualitative analysis of conceptual designs and their optimisation
Dynamics of transcription factor binding site evolution
Evolution of gene regulation is crucial for our understanding of the
phenotypic differences between species, populations and individuals.
Sequence-specific binding of transcription factors to the regulatory regions on
the DNA is a key regulatory mechanism that determines gene expression and hence
heritable phenotypic variation. We use a biophysical model for directional
selection on gene expression to estimate the rates of gain and loss of
transcription factor binding sites (TFBS) in finite populations under both
point and insertion/deletion mutations. Our results show that these rates are
typically slow for a single TFBS in an isolated DNA region, unless the
selection is extremely strong. These rates decrease drastically with increasing
TFBS length or increasingly specific protein-DNA interactions, making the
evolution of sites longer than ~10 bp unlikely on typical eukaryotic speciation
timescales. Similarly, evolution converges to the stationary distribution of
binding sequences very slowly, making the equilibrium assumption questionable.
The availability of longer regulatory sequences in which multiple binding sites
can evolve simultaneously, the presence of "pre-sites" or partially decayed old
sites in the initial sequence, and biophysical cooperativity between
transcription factors, can all facilitate gain of TFBS and reconcile
theoretical calculations with timescales inferred from comparative genetics.Comment: 28 pages, 15 figure
Fluctuations of the Casimir-Polder force between an atom and a conducting wall
We consider the quantum fluctuations of the Casimir-Polder force between a
neutral atom and a perfectly conducting wall in the ground state of the system.
In order to obtain the atom-wall force fluctuation we first define an operator
directly associated to the force experienced by the atom considered as a
polarizable body in an electromagnetic field, and we use a time-averaged force
operator in order to avoid ultraviolet divergences appearing in the fluctuation
of the force. This time-averaged force operator takes into account that any
measurement involves a finite time. We also calculate the Casimir-Polder force
fluctuation for an atom between two conducting walls. Experimental
observability of these Casimir-Polder force fluctuations is also discussed, as
well as the dependence of the relative force fluctuation on the duration of the
measurement.Comment: 6 page
Evolution of new regulatory functions on biophysically realistic fitness landscapes
Regulatory networks consist of interacting molecules with a high degree of
mutual chemical specificity. How can these molecules evolve when their function
depends on maintenance of interactions with cognate partners and simultaneous
avoidance of deleterious "crosstalk" with non-cognate molecules? Although
physical models of molecular interactions provide a framework in which
co-evolution of network components can be analyzed, most theoretical studies
have focused on the evolution of individual alleles, neglecting the network. In
contrast, we study the elementary step in the evolution of gene regulatory
networks: duplication of a transcription factor followed by selection for TFs
to specialize their inputs as well as the regulation of their downstream genes.
We show how to coarse grain the complete, biophysically realistic
genotype-phenotype map for this process into macroscopic functional outcomes
and quantify the probability of attaining each. We determine which evolutionary
and biophysical parameters bias evolutionary trajectories towards fast
emergence of new functions and show that this can be greatly facilitated by the
availability of "promiscuity-promoting" mutations that affect TF specificity
Contributions of Vacuum and Plasmon Modes to the Force on a Small Sphere near a Plate
The force on a small sphere with a plasma model dielectric function and in
the presence of a perfectly reflecting plane is considered. The contribution of
both the vacuum modes of the quantized electromagnetic field and of plasmon
modes in the sphere are discussed. In the case that the plasmon modes are in
their ground state, quasi-oscillatory terms from the vacuum and plasmon parts
cancel one another, leading a monotonic attractive force. If the plasmon modes
are not in the ground state, the net force is quasi-oscillatory. In both cases,
the sphere behaves in the same way as does an atom in either its ground state
or an excited state.Comment: 7 pages, no figures, talk presented at "Quantum Fields under External
Conditions - 2005", Barcelona, Spain, September 200
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