Bio-cultural refugia - Safeguarding diversity of practices for food security and biodiversity

Food security for a growing world population is high on the list of grand sustainability challenges, as is reducing the pace of biodiversity loss in landscapes of food production. Here we shed new insights on areas that harbor place specific social memories related to food security and stewardship of biodiversity. We call them bio-cultural refugia. Our goals are to illuminate how bio-cultural refugia store, revive and transmit memory of agricultural biodiversity and ecosystem services, and how such social memories are carried forward between people and across cohorts. We discuss the functions of such refugia for addressing the twin goals of food security and biodiversity conservation in landscapes of food production. The methodological approach is first of its kind in combining the discourses on food security, social memory and biodiversity management. We find that the rich biodiversity of many regionally distinct cultural landscapes has been maintained through a mosaic of management practices that have co-evolved in relation to local environmental fluctuations, and that such practices are carried forward by both biophysical and social features in bio-cultural refugia including; genotypes, artifacts, written accounts, as well as embodied rituals, art, oral traditions and self-organized systems of rules. Combined these structure a diverse portfolio of practices that result in genetic reservoirs-source areas-for the wide array of species, which in interplay produce vital ecosystem services, needed for future food security related to environmental uncertainties, volatile financial markets and large scale conflicts. In Europe, processes related to the large-scale industrialization of agriculture threaten such bio-cultural refugia. The paper highlights that the dual goals to reduce pressures from modern agriculture on biodiversity, while maintaining food security, entails more extensive collaboration with farmers oriented toward ecologically sound practices. (C) 2013 Elsevier Ltd. All rights reserved

Social Sustainability and Alexander's Living Structure Through a New Kind of City Science

The disputed endorsement of inherited visceral and universal aesthetic preferences justifies the scientific validity of Alexander's living structure. Apart from implying a resource-efficient way to promote well-being through urban design, the premise favors a collective approach to human self-perception and social justice. To better understand the contributions of Alexander, this article explores current knowledge about visceral and universal aesthetic preferences for living structure and if and how the new kind of city science, a mathematical model describing living structure, can be used for further testing. It also elaborates on the social impact of living structure, including its premise, and the potential of the new kind of city science to support social sustainability. A literature synthesis on living structure, the new kind of city science, and the premise showed a positive link between well-being and exposure to living structure. Limitations in research design nevertheless precluded conclusions about the associated visceral and universal aesthetic preferences. The new kind of city science was found appropriate for further research by holistically representing living structure. Moreover, like the hypothesized biological origin, social learning and sociocultural transmission were found to theoretically support the premise of universality and a collective approach to human identity and social justice, with further societal implications. For the concept of living structure to support social sustainability, it must be coupled with the promotion of empowerment and community mobilization. Hence, the operationalization of the new kind of city science should align with Alexander's call for bottom-up approaches

Mapping Flood Risk Uncertainty Zones in Support of Urban Resilience Planning

River flooding and urbanization are processes of different character that take place worldwide. As the latter tends to make the consequences of the former worse, together with the uncertainties related to future climate change and flood-risk modeling, there is a need to both use existing tools and develop new ones that help the management and planning of urban environments. In this article a prototype tool, based on estimated maximum land cover roughness variation, the slope of the ground, and the quality of the used digital elevation models, and that can produce flood ‘uncertainty zones’ of varying width around modeled flood boundaries, is presented. The concept of uncertainty, which urban planners often fail to consider in the spatial planning process, changes from something very difficult into an advantage in this way. Not only may these uncertainties be easier to understand by the urban planners, but the uncertainties may also function as a communication tool between the planners and other stakeholders. Because flood risk is something that urban planners always need to consider, these uncertainty zones can function both as buffer areas against floods, and as blue-green designs of significant importance for a variety of ecosystem services. As the Earth is warming and the world is urbanizing at rates and scales unprecedented in history, we believe that new tools for urban resilience planning are not only urgently needed, but also will have a positive impact on urban planning

Engaging with the pragmatics of relational thinking, leverage points and transformations – Reply to West et al.

Peer reviewe

Promoting Partnership between Urban Design and Urban Ecology through Social-Ecological Resilience Building

A closer partnership between urban design and urban ecology can yield new knowledge with the predictive advancement of both fields. However, achieving such partnership is not always a straight-forward process due to different epistemological departures. This chapter provides a rudimentary background of the fields of urban design and urban ecology and familiarizes readers with some epistemological characteristics that are useful to consider in all forms of partnership activities between designers and ecologists. Social-ecological resilience offers a useful framework for inquiry of particular relevance for urban transition at a time when global societal challenges of massive biodiversity loss and climate change require urgent attention and where wicked environmental problems require creative urban tinkering. Such a framework could open up for more dynamic research approaches with a greater potential to bridge the gap between design and ecology that has tended to be dominated by relatively static design approaches in the past, ignoring a more non-linear understanding of the interconnectedness of social and ecological systems. The chapter ends by focusing on some important determinants for cooperation and dealing with ‘Research Through Design(ing)’ as a viable methodology for transition to urban sustainability

Transcatheter aortic valve implantation: predictors of procedural success—the Siegburg-Bern experience

Aims The purpose of the present analysis was to identify predictors of procedural success of percutaneous transcatheter aortic valve implantation (TAVI). Methods and results We prospectively assessed in-hospital outcome of patients undergoing TAVI at two institutions. We analysed clinical, morphological, and procedural parameters using univariate and multivariate regression models. Between 2005 and 2008, a total of 168 consecutive patients with symptomatic aortic valve stenosis underwent TAVI using the self-expanding CoreValve Revalving prosthesis. Patients (93%) were highly symptomatic with a New York Heart Association grade III/IV and a mean aortic valve area of 0.66 ± 0.21 cm2. Acute and in-hospital procedural success rates were 90.5 and 83.9%, respectively, with an in-hospital mortality, myocardial infarction, and stroke rate of 11.9, 1.8, and 3.6%, respectively. Predictors of in-hospital procedural success were type of access (OR 0.33, 95% CI 0.13-0.82, P = 0.017), prior coronary intervention (OR 5.3, 95% CI 1.20-23.41, P = 0.028) and pre-procedural Karnofsky index using univariate regression. Pre-procedural Karnofsky index emerged as the only independent predictor (OR 1.04, 95% CI 1.00-1.08, P = 0.032) in the multivariate analysis. Conclusion Pre-procedural functional performance status predicts the in-hospital outcome after TAVI. Patients with a good functional status are likely to benefit more from TAVI than previously reported high-risk patient

Human–nature connection: a multidisciplinary review

In sustainability science calls are increasing for humanity to (re-)connect with nature, yet no systematic synthesis of the empirical literature on human–nature connection (HNC) exists. We reviewed 475 publications on HNC and found that most research has concentrated on individuals at local scales, often leaving ‘nature’ undefined. Cluster analysis identified three subgroups of publications: first, HNC as mind, dominated by the use of psychometric scales, second, HNC as experience, characterised by observation and qualitative analysis; and third, HNC as place, emphasising place attachment and reserve visitation. To address the challenge of connecting humanity with nature, future HNC scholarship must pursue cross-fertilization of methods and approaches, extend research beyond individuals, local scales, and Western societies, and increase guidance for sustainability transformations

Damaged Neocortical Perineuronal Nets Due to Experimental Focal Cerebral Ischemia in Mice, Rats and Sheep

As part of the extracellular matrix (ECM), perineuronal nets (PNs) are polyanionic, chondroitin sulfate proteoglycan (CSPG)-rich coatings of certain neurons, known to be affected in various neural diseases. Although these structures are considered as important parts of the neurovascular unit (NVU), their role during evolution of acute ischemic stroke and subsequent tissue damage is poorly understood and only a few preclinical studies analyzed PNs after acute ischemic stroke. By employing three models of experimental focal cerebral ischemia, this study was focused on histopathological alterations of PNs and concomitant vascular, glial and neuronal changes according to the NVU concept. We analyzed brain tissues obtained 1 day after ischemia onset from: (a) mice after filament-based permanent middle cerebral artery occlusion (pMCAO); (b) rats subjected to thromboembolic MACO; and (c) sheep at 14 days after electrosurgically induced focal cerebral ischemia. Multiple fluorescence labeling was applied to explore simultaneous alterations of NVU and ECM. Serial mouse sections labeled with the net marker Wisteria floribunda agglutinin (WFA) displayed largely decomposed and nearly erased PNs in infarcted neocortical areas that were demarcated by up-regulated immunoreactivity for vascular collagen IV (Coll IV). Subsequent semi-quantitative analyses in mice confirmed significantly decreased WFA-staining along the ischemic border zone and a relative decrease in the directly ischemia-affected neocortex. Triple fluorescence labeling throughout the three animal models revealed up-regulated Coll IV and decomposed PNs accompanied by activated astroglia and altered immunoreactivity for parvalbumin, a calcium-binding protein in fast-firing GABAergic neurons which are predominantly surrounded by neocortical PNs. Furthermore, ischemic neocortical areas in rodents simultaneously displayed less intense staining of WFA, aggrecan, the net components neurocan, versican and the cartilage link protein (CRTL) as well as markers in net-bearing neurons such as the potassium channel subunit Kv3.1b and neuronal nuclei (NeuN). In summary, theconsistent observations based on three different stroke models confirmed that PNs are highly sensitive constituents of the NVU along with impaired associated GABAergic neurons. These results suggest that PNs could be promising targets of future stroke treatment, and further studies should address their reorganization and plasticity in both stabilizing the acute stroke as well as supportive effects during the chronic phase of stroke