The rhetoric of disability : a Foucauldian discourse analysis.

The institution of disability, as it is perceived in the United States and most of Western civilization, signifies a site of oppression that has been historically neglected if not actively rejected by the hegemonic population of nondisabled people. While disability studies has congregated as a concerted effort of academic inquiry, scholars have largely approached disability from cultural and sociological perspectives and have focused on physical rather than cognitive disabilities. The field of rhetoric, as the study of discourse and its relation to the production and reception of meaning, offers vital perspectives for better understanding the institution of disability and may serve as a framework for first illuminating and then disempowering the discursive structures that have heretofore suggested that people with disabilities are deviant and inferior. This exposition aims to trace how and in what contexts the concept of disability has been formed as a rhetorical object via Foucauldian discourse analysis. The findings of this research elucidate how the disabled person has come to be known as a subject of the domain of disability through discursive knowledge-power relations. Though a rhetorical analysis may not alleviate the physical, intellectual, or emotional obstacles that may occur from the phenomena of disability, this project represents one step toward reshaping the oppressive paradigm of cultural thought regarding disability and the unjust hierarchization of human ability and worth

Evidence that TRPM8 is an androgen-dependent Ca2+ channel required for the survival of prostate cancer cells

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A Shift in Systems: (Co-)conceptualising Pedagogy in an Era of Continuous Complexity

As a result of complex co-constructive entanglements of contemporary lived-ex-perience, this paper develops ideas from posthumanist and material perspectives on education, that recognise, unpack and analyse the particular dynamic, co-con-structive nature of the postdigital entanglements of technology with the epistemic and ontological development of students (Bozalek, Braidotti, Shefer and Zemby-las, 2018). Drawing from Haraway’s idea of symbiogenesis, (2016), this paper suggests that a critical facet of contemporary pedagogy requires an understanding of the key skill of poiesis, to render visible the entangled ontology of the contem-porary postdigital adolescent to better inform appropriate pedagogic developments

Comparison of Mouse Ly5a and Ly5b Leucocyte Common Antigen Alleles

The family of leucocyte common antigen (LCA) transmembrane glycoproteins is expressed in most hematopoietic cells. Molecular isoforms of the LCA molecule are generated by alternative splicing of a single gene encoded on the murine chromosome 1. Three LCA alleles with different antigenic reactivities have been identified in inbred mouse strains. To investigate the divergence between alleles, cDNA clones to the SJA (Ly5a) LCA gene have been isolated and sequenced. A comparison of this information to the Ly5b allele sequence identifies 12 allele-specific nucleotide changes. These base substitutions correspond to five amino-acid changes within the extracellular domain of the LCA molecule. These amino-acid differences are clustered in a region that also contains the greatest divergence between mouse and rat LCA sequences. Thus, these two mouse LCA alleles exhibit a pattern of sequence conservation that mimics that found over a much broader scale of evolution. Analysis of antigenicity profiles for each of the allelic sequence changes reveals three molecular domains of altered antigenicity that could account for observed serological differences between the two alleles. Sequence information from the 5' end of the Ly5a LCA gene, generated using polymerase chain-reaction techniques on genomic DNA, reveals eight additional nucleotide differences between the Ly5a and Ly5b alleles

Decreasing Mortality Among Patients Hospitalized With Cirrhosis in the United States From 2002 Through 2010

It is not clear whether evidence-based recommendations for inpatient care of patients with cirrhosis are implemented widely or are effective in the community. We investigated changes in inpatient outcomes and associated features over time

Do Genetic Markers of Inflammation Modify the Relationship between Periodontitis and Nonalcoholic Fatty Liver Disease? Findings from the SHIP Study

An association between periodontitis and nonalcoholic fatty liver disease (NAFLD) has been reported by experimental animal and epidemiologic studies. This study investigated whether circulating levels of serum C-reactive protein (CRP) and a weighted genetic CRP score representing markers of inflammatory burden modify the association between periodontitis and NAFLD. Data came from 2,481 participants of the Study of Health in Pomerania who attended baseline examination that occurred between 1997 and 2001. Periodontitis was defined as the percentage of sites (0%, 3 mg/L. Periodontitis was positively associated with higher prevalence odds of NAFLD, and this relationship was modified by serum CRP levels

Howard walnut trees can be brought into bearing without annual pruning

In traditionally managed Howard walnut orchards, trees are pruned annually during the orchard development phase, an expensive operation in terms of labor and prunings disposal costs. Our observations and some prior research by others had suggested that pruning may not be necessary in walnut. In a trial of pruned and unpruned hedgerow trees over 8 years, beginning a year after planting, we documented canopy growth, tree height, yield and nut quality characteristics and also the effects of fruit removal. Pruning altered canopy shape but did not lead to increases in canopy development, yield or nut quality. Although fruit removal stimulated more vegetative growth in both the pruned and unpruned treatments, fruit removal did not result in an increase in midday canopy photosynthetically active radiation interception or cumulative yield when fruit removal was stopped after year 4. After 8 years, there were no significant differences in tree height, nut quality or cumulative yield among any of the treatments, which suggests that not pruning young Howard orchards could provide a net benefit to growers

“I've Had Too Much Done to My Heart”: The Dilemma of Addiction and Recovery as Seen through Seven Youngsters' Lives

Aware of the dearth of in-depth studies on recovering adolescent addict/alcoholics, we conducted a year-long qualitative study of seven formerly-addicted youth committed to recovery. The research question was: how do addicted youth become and remain sober? Bending to social stress, including racism and ethnic prejudice, three participants relapsed. However, personal commitment augmented by familial, community, spiritual, and educational support encouraged four to remain sober. Learning from both those who failed and succeeded, the theoretical concepts of surrender, social stress, and resiliency helped to interpret the participants' patterns of response and better understand adolescent recovery.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline

Uncertainty prior to pulmonary rehabilitation in primary care

Pulmonary rehabilitation (PR) is recommended for patients functionally restricted by chronic obstructive pulmonary disease (COPD). However, attendance and adherence to PR remains suboptimal. No previous research has explored COPD patient experiences during the key period from referral to initiation of PR in the United Kingdom. This research aimed to explore the lived experience of COPD patients referred to PR programmes prior to participation. COPD participants were recruited from referrals to two community PR programmes. Semi-structured interviews withCOPDparticipants occurred followingPRreferral, but prior to programme initiation. Data were analyzed using applied interpretive phenomenology. Twenty-five COPD participants aged 42–90 were interviewed. ‘Uncertainty’ affected participants throughout their lived experience of COPD that negatively impacted illness perceptions, PR perceptions and increased participant’s panic and anger. Participants who perceivedCOPDless as a chronic condition andmore as a cyclical process experienced fewer feelings of panic or anger. The experience of uncertainty was disabling for these COPD participants. Recognition of the role that uncertainty plays in patients withCOPDis the first step towards developing interventions focused on reducing this uncertainty, thereby reducing the burden of the disease for the individual patient and facilitating PR attendance.NHS Education South Centra