1,443 research outputs found

    The Spirit Of Lockport

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    Photograph of high school bandhttps://scholarsjunction.msstate.edu/cht-sheet-music/5474/thumbnail.jp

    Teen, Parent, and Clinician Expectations About Obesity and Related Conditions During the Annual Well-Child Visit

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    Purpose: This study aimed to examine family (patient, parent/guardian) and clinician preferences for identification and management of obesity and obesity-related conditions during the well-child visit. Methods: Four focus groups with teen patients (n = 16), four focus groups with parents (n = 15) and one focus group with providers (n = 12) were conducted using a structured moderator guide tailored to each population. Eligible patients had a well-child visit during the past 12 months and a diagnosis of overweight, obesity, hyperlipidemia or elevated blood pressure. Parents who attended their child’s well-child visit and whose child met the diagnostic criteria were eligible. Teen focus groups were divided by gender (male/female) and age (14–15/16–17 years). Focus group transcripts were coded for concepts and themes using qualitative data and thematic analysis. Analysis was performed across groups to determine common themes and domains of intersect. Results: Teens and parents expect weight to be discussed at well-child visits and prefer discussions to come from a trusted clinician who uses serious, consistent language. Teens did not recognize the health implications from excess weight, and both parents and teens express the need for more information on strategies to change behavior. Providers recognize several challenges and barriers to discussing weight management in the well-child visit. Conclusions: A clinician-teen-family relationship built on trust, longevity, teamwork, support and encouragement can create a positive atmosphere and may improve understanding for weight-related messages for teens and families during a well-child visit

    Control of Josephson current by Aharonov-Casher Phase in a Rashba Ring

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    We study the interference effect induced by the Aharonov-Casher phase on the Josephson current through a semiconducting ring attached to superconducting leads. Using a 1D model that incorporates spin-orbit coupling in the semiconducting ring, we calculate the Andreev levels analytically and numerically, and predict oscillations of the Josephson current due to the AC phase. This result is valid from the point contact limit to the long channel length limit, as defined by the ratio of the junction length and the BCS healing length. We show in the long channel length limit that the impurity scattering has no effect on the oscillation of the Josephson current, in contrast to the case of conductivity oscillations in a spin-orbit coupled ring system attached to normal leads where impurity scattering reduces the amplitude of oscillations. Our results suggest a new scheme to measure the AC phase with, in principle, higher sensitivity. In addition, this effect allows for control of the Josephson current through the gate voltage tuned AC phase.Comment: 12pages, 8 figure

    Phase-Locking of Vortex Lattices Interacting with Periodic Pinning

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    We examine Shapiro steps for vortex lattices interacting with periodic pinning arrays driven by AC and DC currents. The vortex flow occurs by the motion of the interstitial vortices through the periodic potential generated by the vortices that remain pinned at the pinning sites. Shapiro steps are observed for fields B_{\phi} < B < 2.25B_{\phi} with the most pronouced steps occuring for fields where the interstitial vortex lattice has a high degree of symmetry. The widths of the phase-locked current steps as a function of the magnitude of the AC driving are found to follow a Bessel function in agreement with theory.Comment: 5 pages 5 postscript figure

    NIRCam coronagraphic Lyot stop: design, fabrication, and testing

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    The NIRCam instrument on the James Webb Space Telescope (JWST) will provide a coronagraphic imaging capability to search for extrasolar planets in the 2 - 5 microns wavelength range. This capability is realized by a set of Lyot pupil stops with patterns matching the occulting mask located in the JWST intermediate focal plane in the NIRCam optical system. The complex patterns with transparent apertures are made by photolithographic process using a metal coating in the opaque region. The optical density needs to be high for the opaque region, and transmission needs to be high at the aperture. In addition, the Lyot stop needs to operate under cryogenic conditions. We will report on the Lyot stop design, fabrication and testing in this paper

    A Glimpse of the Stellar Populations and Elemental Abundances of Gravitationally Lensed, Quiescent Galaxies at z1z\gtrsim 1 with Keck Deep Spectroscopy

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    Gravitational lenses can magnify distant galaxies, allowing us to discover and characterize the stellar populations of intrinsically faint, quiescent galaxies that are otherwise extremely difficult to directly observe at high redshift from ground-based telescopes. Here, we present the spectral analysis of two lensed, quiescent galaxies at z1z\gtrsim 1 discovered by the ASTRO 3D Galaxy Evolution with Lenses survey: AGEL1323 (M1011.1MM_*\sim 10^{11.1}M_{\odot}, z=1.016z=1.016, μ14.6\mu \sim 14.6) and AGEL0014 (M1011.3MM_*\sim 10^{11.3}M_{\odot}, z=1.374z=1.374, μ4.3\mu \sim 4.3). We measured the age, [Fe/H], and [Mg/Fe] of the two lensed galaxies using deep, rest-frame-optical spectra (S/N \gtrsim 40\AA1^{-1}) obtained on the Keck I telescope. The ages of AGEL1323 and AGEL0014 are 5.60.8+0.85.6^{+0.8}_{-0.8} Gyr and 3.10.3+0.83.1^{+0.8}_{-0.3} Gyr, respectively, indicating that most of the stars in the galaxies were formed less than 2 Gyr after the Big Bang. Compared to nearby quiescent galaxies of similar masses, the lensed galaxies have lower [Fe/H] and [Mg/H]. Surprisingly, the two galaxies have comparable [Mg/Fe] to similar-mass galaxies at lower redshifts, despite their old ages. Using a simple analytic chemical evolution model connecting the instantaneously recycled element Mg with the mass-loading factors of outflows averaged over the entire star formation history, we found that the lensed galaxies may have experienced enhanced outflows during their star formation compared to lower-redshift galaxies, which may explain why they quenched early.Comment: 18 pages, 11 figures, submitted to ApJ; comments welcom

    Cold atoms in space: community workshop summary and proposed road-map

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    We summarise the discussions at a virtual Community Workshop on Cold Atoms in Space concerning the status of cold atom technologies, the prospective scientific and societal opportunities offered by their deployment in space, and the developments needed before cold atoms could be operated in space. The cold atom technologies discussed include atomic clocks, quantum gravimeters and accelerometers, and atom interferometers. Prospective applications include metrology, geodesy and measurement of terrestrial mass change due to, e.g., climate change, and fundamental science experiments such as tests of the equivalence principle, searches for dark matter, measurements of gravitational waves and tests of quantum mechanics. We review the current status of cold atom technologies and outline the requirements for their space qualification, including the development paths and the corresponding technical milestones, and identifying possible pathfinder missions to pave the way for missions to exploit the full potential of cold atoms in space. Finally, we present a first draft of a possible road-map for achieving these goals, that we propose for discussion by the interested cold atom, Earth Observation, fundamental physics and other prospective scientific user communities, together with the European Space Agency (ESA) and national space and research funding agencies

    Sustained proliferation in cancer: mechanisms and novel therapeutic targets

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    Proliferation is an important part of cancer development and progression. This is manifest by altered expression and/or activity of cell cycle related proteins. Constitutive activation of many signal transduction pathways also stimulates cell growth. Early steps in tumor development are associated with a fibrogenic response and the development of a hypoxic environment which favors the survival and proliferation of cancer stem cells. Part of the survival strategy of cancer stem cells may manifested by alterations in cell metabolism. Once tumors appear, growth and metastasis may be supported by overproduction of appropriate hormones (in hormonally dependent cancers), by promoting angiogenesis, by undergoing epithelial to mesenchymal transition, by triggering autophagy, and by taking cues from surrounding stromal cells. A number of natural compounds (e.g., curcumin, resveratrol, indole-3-carbinol, brassinin, sulforaphane, epigallocatechin-3-gallate, genistein, ellagitannins, lycopene and quercetin) have been found to inhibit one or more pathways that contribute to proliferation (e.g., hypoxia inducible factor 1, nuclear factor kappa B, phosphoinositide 3 kinase/Akt, insulin-like growth factor receptor 1, Wnt, cell cycle associated proteins, as well as androgen and estrogen receptor signaling). These data, in combination with bioinformatics analyses, will be very important for identifying signaling pathways and molecular targets that may provide early diagnostic markers and/or critical targets for the development of new drugs or drug combinations that block tumor formation and progression

    Search for Charginos with a Small Mass Difference with the Lightest Supersymmetric Particle at \sqrt{s} = 189 GeV

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    A search for charginos nearly mass-degenerate with the lightest supersymmetric particle is performed using the 176 pb^-1 of data collected at 189 GeV in 1998 with the L3 detector. Mass differences between the chargino and the lightest supersymmetric particle below 4 GeV are considered. The presence of a high transverse momentum photon is required to single out the signal from the photon-photon interaction background. No evidence for charginos is found and upper limits on the cross section for chargino pair production are set. For the first time, in the case of heavy scalar leptons, chargino mass limits are obtained for any \tilde{\chi}^{+-}_1 - \tilde{\chi}^0_1 mass difference
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