Preliminary Results From the Long-Term Inmate Survey: Focus on Child Abuse Histories

This preliminary report of long-term inmates in Alaska correctional facilities finds that over 80 percent of long-term inmates report having been physically abused as children, over 65 percent report having suffered neglect. Other findings related to the child abuse histories of long-term inmates are also reported.Alaska Department of Correction

Results From the Long-Term Inmate Survey: Focus on Child Abuse Histories

This report of long-term inmates in Alaska correctional facilities attempts to describe the childhood experiences of a sample of long-term inmates, address the "cycle of abuse" issue; and present the correlates of abuse which may impact the pattern of offending or inmate functioning. Over 80 percent of long-term inmates report having been physically abused as children; over 65 percent report having suffered neglect.Alaska Department of CorrectionsResults from the Long Term Inmate Study: Focus on Child Abuse Histories / Incidence of Child Abuse and the Relationship to Criminality / Measuring Child Abuse and Neglect: A Review of Methods / Survey Methods and Administration / An Assessment of Survey Biases / Tables to Support Profile Analysis / Personal Interview Administration and Results / Correlates of Abus

Bending and Tensile Properties of Vapor Boron-Treated Composites

North American composites, including laminated veneer lumber, oriented strandboard, and medium density fiberboard, were treated by vapor boron technology and subsequently tested in static bending. Tensile properties were also determined for the two composite board products. The study was designed as a 2 x 3 factorial with two mill locations and three treatment levels for each composite type. In general, mill location significantly affected most property values, while treatment level caused only significant reductions at the highest treatment level. The significance of mill location was attributed mainly to species differences since species varied between locations for each composite type

Tidal Evolution of Close-in Extra-Solar Planets

The distribution of eccentricities e of extra-solar planets with semi-major axes a > 0.2 AU is very uniform, and values for e are relatively large, averaging 0.3 and broadly distributed up to near 1. For a < 0.2 AU, eccentricities are much smaller (most e < 0.2), a characteristic widely attributed to damping by tides after the planets formed and the protoplanetary gas disk dissipated. Most previous estimates of the tidal damping considered the tides raised on the planets, but ignored the tides raised on the stars. Most also assumed specific values for the planets' poorly constrained tidal dissipation parameter Qp. Perhaps most important, in many studies, the strongly coupled evolution between e and a was ignored. We have now integrated the coupled tidal evolution equations for e and a over the estimated age of each planet, and confirmed that the distribution of initial e values of close-in planets matches that of the general population for reasonable Q values, with the best fits for stellar and planetary Q being ~10^5.5 and ~10^6.5, respectively. The accompanying evolution of a values shows most close-in planets had significantly larger a at the start of tidal migration. The earlier gas disk migration did not bring all planets to their current orbits. The current small values of a were only reached gradually due to tides over the lifetimes of the planets. These results may have important implications for planet formation models, atmospheric models of "hot Jupiters", and the success of transit surveys.Comment: accepted to Ap

Does the Isotropy of the CMB Imply a Homogeneous Universe? Some Generalised EGS Theorems

We demonstrate that the high isotropy of the Cosmic Microwave Background (CMB), combined with the Copernican principle, is not sufficient to prove homogeneity of the universe -- in contrast to previous results on this subject. The crucial additional factor not included in earlier work is the acceleration of the fundamental observers. We find the complete class of irrotational perfect fluid spacetimes admitting an exactly isotropic radiation field for every fundamental observer and show that are FLRW if and only if the acceleration is zero. While inhomogeneous in general, these spacetimes all possess three-dimensional symmetry groups, from which it follows that they also admit a thermodynamic interpretation. In addition to perfect fluids models we also consider multi-component fluids containing non-interacting radiation, dust and a quintessential scalar field or cosmological constant in which the radiation is isotropic for the geodesic (dust) observers. It is shown that the non-acceleration of the fundamental observers forces these spacetimes to be FLRW. While it is plausible that fundamental observers (galaxies) in the real universe follow geodesics, it is strictly necessary to determine this from local observations for the cosmological principle to be more than an assumption. We discuss how observations may be used to test this.Comment: replaced with final version. Added discusion and ref

Palmoplantar keratoderma along with neuromuscular and metabolic phenotypes in Slurp1-deficient mice.

Mutations in SLURP1 cause mal de Meleda, a rare palmoplantar keratoderma (PPK). SLURP1 is a secreted protein that is expressed highly in keratinocytes but has also been identified elsewhere (e.g., spinal cord neurons). Here, we examined Slurp1-deficient mice (Slurp1(-/-)) created by replacing exon 2 with β-gal and neo cassettes. Slurp1(-/-) mice developed severe PPK characterized by increased keratinocyte proliferation, an accumulation of lipid droplets in the stratum corneum, and a water barrier defect. In addition, Slurp1(-/-) mice exhibited reduced adiposity, protection from obesity on a high-fat diet, low plasma lipid levels, and a neuromuscular abnormality (hind-limb clasping). Initially, it was unclear whether the metabolic and neuromuscular phenotypes were due to Slurp1 deficiency, because we found that the targeted Slurp1 mutation reduced the expression of several neighboring genes (e.g., Slurp2, Lypd2). We therefore created a new line of knockout mice (Slurp1X(-/-) mice) with a simple nonsense mutation in exon 2. The Slurp1X mutation did not reduce the expression of adjacent genes, but Slurp1X(-/-) mice exhibited all of the phenotypes observed in the original line of knockout mice. Thus, Slurp1 deficiency in mice elicits metabolic and neuromuscular abnormalities in addition to PPK

Eigenvalue bounds for polynomial central potentials in d dimensions

If a single particle obeys non-relativistic QM in R^d and has the Hamiltonian H = - Delta + f(r), where f(r)=sum_{i = 1}^{k}a_ir^{q_i}, 2\leq q_i < q_{i+1}, a_i \geq 0$, then the eigenvalues E = E_{n\ell}^{(d)}(\lambda) are given approximately by the semi-classical expression E = \min_{r > 0}[\frac{1}{r^2} + \sum_{i = 1}^{k}a_i(P_ir)^{q_i}]. It is proved that this formula yields a lower bound if P_i = P_{n\ell}^{(d)}(q_1), an upper bound if$P_i = P_{n\ell}^{(d)}(q_k) and a general approximation formula if P_i = P_{n\ell}^{(d)}(q_i). For the quantum anharmonic oscillator f(r)=r^2+\lambda r^{2m},m=2,3,... in d dimension, for example, E = E_{n\ell}^{(d)}(\lambda) is determined by the algebraic expression \lambda={1\over \beta}({2\alpha(m-1)\over mE-\delta})^m({4\alpha \over (mE-\delta)}-{E\over (m-1)}) where \delta={\sqrt{E^2m^2-4\alpha(m^2-1)}} and \alpha, \beta are constants. An improved lower bound to the lowest eigenvalue in each angular-momentum subspace is also provided. A comparison with the recent results of Bhattacharya et al (Phys. Lett. A, 244 (1998) 9) and Dasgupta et al (J. Phys. A: Math. Theor., 40 (2007) 773) is discussed.Comment: 13 pages, no figure

Advanced magnetic resonance imaging of cartilage components in haemophilic joints reveals that cartilage hemosiderin correlates with joint deterioration.

IntroductionEvidence suggests that toxic iron is involved in haemophilic joint destruction.AimTo determine whether joint iron deposition is linked to clinical and imaging outcomes in order to optimize management of haemophilic joint disease.MethodsAdults with haemophilia A or haemophilia B (n = 23, ≥ age 21) of all severities were recruited prospectively to undergo assessment with Hemophilia Joint Health Scores (HJHS), pain scores (visual analogue scale [VAS]) and magnetic resonance imaging (MRI) at 3T using conventional MRI protocols and 4-echo 3D-UTE-Cones sequences for one affected arthropathic joint. MRI was scored blinded by two musculoskeletal radiologists using the International Prophylaxis Study Group (IPSG) MRI scale. Additionally, UTE-T2* values of cartilage were quantified. Correlations between parameters were performed using Spearman rank correlation. Two patients subsequently underwent knee arthroplasty, which permitted linking of histological findings (including Perl's reaction) with MRI results.ResultsMRI scores did not correlate with pain scores or HJHS. Sixteen joints had sufficient cartilage for UTE-T2* analysis. T2* values for cartilage correlated inversely with HJHS (rs  = -0.81, P &lt; 0.001) and MRI scores (rs  = -0.52, P = 0.037). This was unexpected since UTE-T2* values decrease with better joint status in patients with osteoarthritis, suggesting that iron was present and responsible for the effects. Histological analysis of cartilage confirmed iron deposition within chondrocytes, associated with low UTE-T2* values.ConclusionsIron accumulation can occur in cartilage (not only in synovium) and shows a clear association with joint health. Cartilage iron is a novel biomarker which, if quantifiable with innovative joint-specific MRI T2* sequences, may guide treatment optimization