200 research outputs found

    Carcinoma of the Stomach

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    The Incidence of Cancer

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    1. The crude mortality rates due to cancer in Scotland, Glasgow and the province of Saskatchewan are presented. 2. The practice of using crude mortality rates as an indication of the incidence of cancer is discussed and condemned. 3. A method of correcting the crude mortality rate for over- and under-diagnosis of cancer is presented. 4. The crude incidence of cancer in Saskatchewan has been calculated using all the sources of information available in that province. 5. The age distribution of cancer in Saskatchewan is presented

    The OmegaWhite Survey for Short-Period Variable Stars - I : Overview and First Results

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    We present the goals, strategy and first results of the OmegaWhite survey: a wide-field high-cadence g-band synoptic survey which aims to unveil the Galactic population of short-period variable stars (with periods <80 min), including ultracompact binary star systems and stellar pulsators. The ultimate goal of OmegaWhite is to cover 400 deg2 along the Galactic plane reaching a depth of g = 21.5 mag (10σ), using OmegaCam on the VLT Survey Telescope (VST). The fields are selected to overlap with surveys such as the Galactic Bulge Survey and the VST Photometric Hα Survey of the Southern Galactic Plane for multiband colour information. Each field is observed using 38 exposures of 39 s each, with a median cadence of ∼2.7 min for a total duration of two hours. Within an initial 26 deg2, we have extracted the light curves of 1.6 million stars, and have identified 613 variable candidates which satisfy our selection criteria. Furthermore, we present the light curves and statistical properties of 20 sources which have the highest likelihood of being variable stars. One of these candidates exhibits the colours and light-curve properties typically associated with ultracompact AM CVn binaries, although its spectrum exhibits weak Balmer absorption lines and is thus not likely to be such a binary system. We also present follow-up spectroscopy of five other variable candidates, which identifies them as likely low-amplitude δ Sct pulsating starsPeer reviewe

    Magmatic and tectonic extension at mid-ocean ridges : 2. Origin of axial morphology

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    Author Posting. © American Geophysical Union, 2008. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geochemistry Geophysics Geosystems 9 (2008): Q09O12, doi:10.1029/2008GC001970.We investigate the origin of mid-ocean ridge morphology with numerical models that successfully predict axial topographic highs, axial valleys, and the transition between the two. The models are time-dependent, simulating alternating tectonic and magmatic periods where far-field extension is accommodated by faulting and by magmatism, respectively. During tectonic phases, models predict faults to grow on either side of the ridge axis and axial height to decrease. During magmatic phases, models simulate magmatic extension by allowing the axial lithosphere to open freely in response to extension. Results show that fault size and spacing decreases with increasing time fraction spent in the magmatic phase F M . Magmatic phases also simulate the growth of topography in response to local buoyancy forces. The fundamental variable that controls the transition between axial highs and valleys is the “rise-sink ratio,” (F M /F T )(τ T /τ M ), where F M /F T is the ratio of the time spent in the magmatic and tectonic periods and τ T /τ M is the ratio of the characteristic rates for growing topography during magmatic phases (1/τ M ) and for reducing topography during tectonic phases (1/τ T ). Models predict the tallest axial highs when (F M /F T )(τ T /τ M ) ≫ 1, faulted topography without a high or valley when (F M /F T )(τ T /τ M ) ∼ 1, and the deepest median valleys when (F M /F T )(τ M /τ T ) < 1. New scaling laws explain a global negative correlation between axial topography and lithosphere thickness as measured by the depths of axial magma lenses and microearthquakes. Exceptions to this trend reveal the importance of other behaviors such as a predicted inverse relation between axial topography and spreading rate as evident along the Lau Spreading Center. Still other factors related to the frequency and spatial pervasiveness of magmatic intrusions and eruptions, as evident at the Mid-Atlantic and Juan de Fuca ridges, influence the rise-sink-ratio (F M /F T )(τ T /τ M ) and thus axial morphology.Funding for this research was provided by NSF grants OCE-0327018 (MDB), OCE-0548672 (MDB), OCE-0327051 (GI), and OCE-0351234 (GI)

    Research priorities for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): the results of a James Lind alliance priority setting exercise

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    Objective: To identify research priorities of people with myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) and those who support and care for them. Method: Using the James Lind Alliance’s protocols, online surveys and workshops were held. The first survey asked participants from the U.K. to submit research questions about ME/CFS which were important to them. In the second, participants prioritised frequently submitted questions from the 1st survey. These were short listed and then workshop discussions were held to reach consensus on the top ten research priorities. Results: 1565 participated in the 1st survey and 5300 research priorities were submitted. 1752 participated in the 2nd. In both surveys, the predominant demographic was white, middle-aged women with ME/CFS. 15–17% were family/carers of people with ME/CFS and 4–6% were health and social care workers. From the 1st survey, 59 summary questions were identified. These were prioritised and short listed to 18 questions. Of these, the top 10 covered 1. Post-exertional malaise, 2. Use of existing drugs for other conditions, 3. Diagnosis, 4. Autoimmunity, 5. Sub-types, 6. Post-infective cause, 7. Neurological symptomology, 8. Genetics, 9. Severe ME/CFS, 10. Mitochronical dysfunction and 10 (equal) Oxygenation dysfunction. Conclusion: People with ME/CFS, their families and carers, and health care professionals worked together to identify, for the first time, the research priorities for ME/CFS. These focus on the biomedical causes of ME/CFS and how to diagnose, treat and manage it. Researchers and funding bodies should consider these in their plans for future research
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