Corrigendum: The Influence of Task-Irrelevant Flankers Depends on the Composition of Emotion Categories

Face recognition usually takes place in a social context, where faces are surrounded by other stimuli. These can act as distracting flankers which impair recognition. Previous work has suggested that flankers expressing negative emotions distract more than positive ones. However, the various negative emotions differ in their relative impact and it is unclear whether all negative emotions are equally distracting. We investigated the impact of three negative (angry, fearful, sad) and one positive (happy) facial flanker conditions on target recognition in an emotion discrimination task. We examined the effect of the receiver’s gender, and the impact of two different temporal delays between flanker and target onset, as stimulus onset asynchrony is assumed to affect distractor strength. Participants identified and rated the emotional intensity of target faces surrounded by either face (emotional and neutral) or non-face flankers. Target faces were presented either simultaneously with the flankers, or delayed by 300 ms. Contrary to our hypothesis, negative flankers did not exert stronger distraction effects than positive or neutral flankers. However, happy flankers reduced recognition performance. Results of a follow-up experiment with a balanced number of emotion categories (one positive, one negative and one neutral flanker condition) suggest that the distraction effect of emotional flankers depends on the composition of the emotion categories. Additionally, congruency effects were found to be valence-specific and overruled by threat stimuli. Females responded more quickly and rated targets in happy flankers as less intense. This indicates a gender difference in emotion processing, with greater sensitivity to facial flankers in women. Targets were rated as more intense when they were presented without a temporal delay, possibly due to a stronger flanker contrast. These three experiments show that an exceptional processing of threat-related flanker stimuli depends on emotion category composition, which should be considered a mediating factor when examining emotional context effects

Sex Differences in Personality Disorders

Purpose of ReviewThis review aims to give an overview on the current literature on sex differences in personality disorders and to highlight the potential of dimensional approaches.Recent FindingsEmpirical findings on sex differences in personality disorders are inconsistent and appear to be highly dependent on study settings. Current studies have mainly focused on borderline and antisocial personality disorder and the question whether these are sex-specific representations of a common substrate. In general, sexes differ in the manifestation of personality disorders as well as in comorbidities. Criticism of the established categorical model led to an additional dimensional model of personality disorders in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition.SummaryInvestigations on sex differences in personality disorders are sparse and mainly limited to antisocial and borderline personality disorder. The introduction of a dimensional model offers the chance to re-think the construct of “personality disorder” and thereby also opens the possibility for a better understanding of sex differences

Task-dependent functional organizations of the visual ventral stream

The visual hierarchy of the ventral stream has been widely studied. However, it remains unclear how the hierarchical system organizes its functional coupling during top-down cognitive process. The present fMRI study investigated task-dependent functional connectivity along the ventral stream, while twenty-eight participants performed object recognition tasks that required different types of visual processing: i) searching or ii) memorizing visual objects embedded in natural scene images or iii) free viewing of the same images. Utilizing a seed-based approach that explicitly compared task-specific BOLD time-series, we identified task-dependent functional connectivity of the visual ventral stream, demonstrating different correlation structures. Searching for a target object manifested both correlated and anti-correlated structures, separating the visual areas V1 and V4 from the posterior part of the inferior temporal cortex (PIT). In contrast, the ventral stream structure remained correlated during memorizing objects, but increased the correlation between the right V4 and PIT. On the other hand, V1 and V4 showed task-dependent activation, whereas PIT was deactivated. These results highlight the context-dependent nature of the visual ventral stream and shed light on how the visual hierarchy is selectively organized to bias object recognition toward features of interest

Distinct modes of top-down cognitive processing in the ventral visual cortex

Top-down cognitive control leads to changes in the sensory processing of the brain. In visual perception such changes can take place in the ventral visual cortex altering the functional asymmetry in forward and backward connections. Here we used fixation-related evoked responses of EEG measurement and dynamic causal modeling to examine hierarchical forward-backward asymmetry, while twenty-six healthy adults performed cognitive tasks that require different types of top-down cognitive control (memorizing or searching visual objects embedded in a natural scene image). The generative model revealed an enhanced asymmetry toward forward connections during memorizing, whereas enhanced backward connections were found during searching. This task-dependent modulation of forward and backward connections suggests two distinct modes of top-down cognitive processing in cortical networks. The alteration in forward-backward asymmetry might underlie the functional role in the cognitive control of visual information processing

Task-irrelevant fear enhances amygdala-FFG inhibition and decreases subsequent face processing

Facial threat is associated with changes in limbic activity as well as modifications in the cortical face-related N170. It remains unclear if task-irrelevant threat modulates the response to a subsequent facial stimulus, and whether the amygdala’s role in early threat perception is independent and direct, or modulatory. In 19 participants, crowds of emotional faces were followed by target faces and a rating task while simultaneous EEG-fMRI were recorded. In addition to conventional analyses, fMRI-informed EEG analyses and fMRI dynamic causal modeling (DCM) were performed. Fearful crowds reduced EEG N170 target face amplitudes and increased responses in a fMRI network comprising insula, amygdala and inferior frontal cortex. Multimodal analyses showed that amygdala response was present ∼60 ms before the right fusiform gyrus-derived N170. DCM indicated inhibitory connections from amygdala to fusiform gyrus, strengthened when fearful crowds preceded a target face. Results demonstrated the suppressing influence of task-irrelevant fearful crowds on subsequent face processing. The amygdala may be sensitive to task-irrelevant fearful crowds and subsequently strengthen its inhibitory influence on face-responsive fusiform N170 generators. This provides spatiotemporal evidence for a feedback mechanism of the amygdala by narrowing attention in order to focus on potential threats