Design and application of fuel injection drive circuit for engine test bench

Based on the STM32 library function, this design is developed a good docking with the engine, without changing the engine's original ECU. Only on the test bench, this design which connected to the device can enter the injection pulse width, so as to control the engine mixture concentration. Using this experimental device, the fuel adjustment characteristic experiment was completed on the existing engine test bed, which verified that the experimental device developed by this design had good adaptability in use. In this way, universities and research institutes can use this experimental device to easily complete the fuel adjustment characteristic experiment, and can also provide a convenient tool option for the calibration and optimization of the engine pulse spectrum

Global research trends of Mycoplasma pneumoniae pneumonia in children: a bibliometric analysis

BackgroundMycoplasma pneumoniae pneumonia (MPP), attributable to Mycoplasma pneumoniae (MP), represents a predominant form of community-acquired pneumonia in pediatric populations, thereby posing a significant threat to pediatric health. Given the burgeoning volume of research literature associated with pediatric MPP in recent years, it becomes imperative to undertake a bibliometric analysis aimed at delineating the current research landscape and emerging trends, thereby furnishing a framework for subsequent investigations.MethodsA comprehensive literature search targeting pediatric MPP was conducted in the Web of Science Core Collection. After the removal of duplicate entries through Endnote software, the remaining articles were subject to scientometric analysis via Citespace software, VOSviewer software and R language, focusing on variables such as publication volume, contributing nations, institutions and authors, references and keywords.ResultsA total of 1,729 articles pertinent to pediatric MPP were included in the analysis. China and the United States emerged as the nations with the highest publication output. Italian scholar Susanna Esposito and Japanese scholar Kazunobu Ouchi were the most influential authors in the domain of pediatric MPP. Highly-cited articles primarily focused on the epidemiological investigation of pediatric MPP, the clinical characteristics and treatment of macrolide-resistant MPP, and biomarkers for refractory Mycoplasma pneumoniae pneumonia (RMPP). From the corpus of 1,729 articles, 636 keywords were extracted and categorized into ten clusters: Cluster #0 centered on molecular-level typing of macrolide-resistant strains; Cluster #1 focused on lower respiratory tract co-infections; Clusters #2 and #6 emphasized other respiratory ailments caused by MP; Cluster #3 involved biomarkers and treatment of RMPP; Clusters #4 and #9 pertained to extrapulmonary complications of MPP, Clusters #5 and #7 addressed etiological diagnosis of MPP, and Cluster #8 explored pathogenic mechanisms.ConclusionsThe past few years have witnessed extensive attention directed towards pediatric MPP. Research in pediatric MPP principally revolves around diagnostic techniques for MP, macrolide resistance, complications of MPP, treatment and diagnosis of RMPP, and elucidation of pathogenic mechanisms. The present study provides pediatric clinicians and researchers with the research status and focal points in this field, thereby guiding the orientation of future research endeavors

MoWLD: A Robust Motion Image Descriptor for Violence Detection

Abstract Automatic violence detection from video is a hot topic for many video surveillance applications. However, there has been little success in designing an algorithm that can detect violence in surveillance videos with high performance. Existing methods typically apply the Bagof-Words (BoW) model on local spatiotemporal descriptors. However, traditional spatiotemporal features are not discriminative enough, and also the BoW model roughly assigns each feature vector to only one visual word and therefore ignores the spatial relationships among the features. To tackle these problems, in this paper we propose a novel Motion Weber Local Descriptor (MoWLD) in the spirit of the well-known WLD and make it a powerful and robust descriptor for motion images. We extend the WLD spatial descriptions by adding a temporal component to the appearance descriptor, which implicitly captures local motion information as well as low-level image appear information. To eliminate redundant and irrelevant features, the nonparametric Kernel Density Estimation (KDE) is employed on the MoWLD descriptor. In order to obtain more discriminative features, we adopt the sparse coding and max pooling scheme to further process the selected MoWLDs. Experimental results on three benchmark datasets have demonstrated the superiority of the proposed approach over the state-of-the-arts

Ring-Pins combined with cable cerclage for the fixation of displaced inferior patellar pole fractures

ObjectiveThe study aimed to present the clinical results and complication rates of ring-pins with cable cerclage for treating the inferior pole of patella fracture.MethodA study that retrospectively reviewed consecutive patients of the displaced inferior pole of patella fracture (AO/OTA 34-A1) operated with a ring-pin tension band using cable cerclage between October 2015 and October 2017 was performed. The duration of surgery, motion range of the knee, function outcomes, and complications were recorded.ResultsThe average follow-up of 31 patients was 21 months. The mean operation time was 50 min. Fractures in all 31 patients healed at a mean duration of 8 weeks. There was no infection, no withdrawing of ring-pins, no implant breakage, and no loss of fracture reduction. The mean range of motion was 120°, and no patient complained of implant irritation at the final follow-up. The average Bostman score was 29.0 points, and 28 patients graded clinical outcomes excellent and 3 patients graded clinical outcomes good at the last follow-up.ConclusionsRing-pin combined with cable cerclage for treating the displaced inferior pole of patellar fracture is simple, and the postoperative internal fixation-related complication rate is low. It is a good choice for treating the displaced inferior pole of the patellar fracture

Analyses of a chromosome-scale genome assembly reveal the origin and evolution of cultivated chrysanthemum

DATA AVAILABILITY : The raw sequencing data generated in this study have been deposited in the NCBI under accession PRJNA796762 and PRJNA895586 The chloroplast andmitochondrial genome were also available at GenBank under the accession number OP104251 and OP104742 respectively. The assembled genome sequences and annotations are available at Figshare [https://doi.org/10.6084/m9.figshare.21655364.v2]. The Arabidopsis ABCE and chrysanthemum CYC2 genes were used as query sequences for gene family identification, which are available at Figshare [https://doi.org/10.6084/m9.figshare.21610305]. Source data are provided with this paper.Chrysanthemum (Chrysanthemum morifolium Ramat.) is a globally important ornamental plant with great economic, cultural, and symbolic value. However, research on chrysanthemum is challenging due to its complex genetic background. Here, we report a near-complete assembly and annotation for C. morifolium comprising 27 pseudochromosomes (8.15 Gb; scaffold N50 of 303.69Mb). Comparative and evolutionary analyses reveal a whole-genome triplication (WGT) event shared by Chrysanthemum species approximately 6 million years ago (Mya) and the possible lineage-specific polyploidization of C. morifolium approximately 3 Mya. Multilevel evidence suggests that C. morifolium is likely a segmental allopolyploid. Furthermore, a combination of genomics and transcriptomics approaches demonstrate the C. morifolium genome can be used to identify genes underlying key ornamental traits. Phylogenetic analysis of CmCCD4a traces the flower colour breeding history of cultivated chrysanthemum. Genomic resources generated from this study could help to accelerate chrysanthemum genetic improvement.The National Natural Science Foundation of China, the Natural Science Fund of Jiangsu Province, China Agriculture Research System, the National Key Research and Development Program of China, the “JBGS” Project of Seed Industry Revitalisation in Jiangsu Province, the European Union’s Horizon 2020 research and innovation program from European Research Council, the Methusalem funding from Ghent University, and a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institution.https://www.nature.com/ncomms/am2024BiochemistryGeneticsMicrobiology and Plant PathologySDG-15:Life on lan

Understanding PRRSV Infection in Porcine Lung Based on Genome-Wide Transcriptome Response Identified by Deep Sequencing

Porcine reproductive and respiratory syndrome (PRRS) has been one of the most economically important diseases affecting swine industry worldwide and causes great economic losses each year. PRRS virus (PRRSV) replicates mainly in porcine alveolar macrophages (PAMs) and dendritic cells (DCs) and develops persistent infections, antibody-dependent enhancement (ADE), interstitial pneumonia and immunosuppression. But the molecular mechanisms of PRRSV infection still are poorly understood. Here we report on the first genome-wide host transcriptional responses to classical North American type PRRSV (N-PRRSV) strain CH 1a infection using Solexa/Illumina's digital gene expression (DGE) system, a tag-based high-throughput transcriptome sequencing method, and analyse systematically the relationship between pulmonary gene expression profiles after N-PRRSV infection and infection pathology. Our results suggest that N-PRRSV appeared to utilize multiple strategies for its replication and spread in infected pigs, including subverting host innate immune response, inducing an anti-apoptotic and anti-inflammatory state as well as developing ADE. Upregulation expression of virus-induced pro-inflammatory cytokines, chemokines, adhesion molecules and inflammatory enzymes and inflammatory cells, antibodies, complement activation were likely to result in the development of inflammatory responses during N-PRRSV infection processes. N-PRRSV-induced immunosuppression might be mediated by apoptosis of infected cells, which caused depletion of immune cells and induced an anti-inflammatory cytokine response in which they were unable to eradicate the primary infection. Our systems analysis will benefit for better understanding the molecular pathogenesis of N-PRRSV infection, developing novel antiviral therapies and identifying genetic components for swine resistance/susceptibility to PRRS

A DOUBLE-LAYER METAMATERIAL WITH NEGATIVE REFRACTIVE INDEX ORIGINATING FROM CHIRAL CONFIGURATION

Metamaterial of twisted metallic foil pans is proposed Resonances are illustrated in both transmission and reflection Negative refraction index can be realized by chiral configuration of this metamaterial Parallel and antiparallel surface cut rents form magnetic and electric dipoles The moss coupling between electric and magnetic field pesetas chirality (C) 2010 Wiley Periodicals Inc Microwave Opt Technol Lett 53 163-166 2011 View this article online at wileyonlinelibrary com DOI 10 1002/mop 2564

Highly transparent conductive AZO/Zr50Cu50/AZO films in wide range of visible and near infrared wavelength grown by pulsed laser deposition

Novel AZO/Zr50Cu50/AZO tri-layer transparent conductive films with excellent transmittance in both visible and near infrared region were successfully prepared by pulsed laser deposition on glass substrates. The electrical and optical properties were investigated at various Zr50Cu50 thicknesses. As the AZO thickness was fixed at 50 nm and Zr50Cu50 thickness was varied between 1 and 18 nm, it was found that AZO (50 nm)/Zr50Cu50/AZO (50 nm) tri-layer films exhibited good conductivity and high transmittance in both visible and near infrared wavelength. Additionally, both the electrical and optical properties of AZO (50 nm)/Zr50Cu50 (2 nm)/AZO (50 nm) tri-layer films were found to be sensitive to the growth temperature. In this work, the lowest sheet resistance (43 Ω/□) and relatively high transmittance (∼80%) in the range of 400–2000 nm were achieved while the growth temperature was 350 °C. Furthermore, the AZO (50 nm)/Zr50Cu50 (2 nm)/AZO (50 nm) thin film deposited at 350 °C exhibits the highest figure of merit of 1.42 × 10−3 Ω−1, indicating that the multilayer is promising for coated glasses and thin film solar cells. Keywords: Transparent conductive oxide, AZO, Zr50Cu50, Electrical and optical properties, Visible and near infrared transmittanc

Carbon Nitride Decorated Ball-Flower like Co3O4 Hybrid Composite: Hydrothermal Synthesis and Ethanol Gas Sensing Application

Recently, semiconducting metal oxide (SMO) gas sensors have attracted the attention of researchers for high conductivity, labile features by environment, low cost, easy preparation, etc. However, traditional SMOs have some defects such as higher operating temperature and lower response value, which greatly limit their application in the field of gas sensor. In this work, the carbon nitride decorated ball-flower like Co3O4 composite was successfully synthesized via a facile hydrothermal method, the composition and morphology of the as-synthesized samples were studied by the techniques of X-ray powder diffraction (XRD), Field-emission scanning electron microscopy (FESEM), Transmission electron microscopy (TEM), Fourier transform infrared spectrometer (FT-IR) and N2-sorption. As a consequence, the pure Co3O4 and the carbon nitride decorated Co3O4 both possess ball-flower like structure, and the as-synthesized carbon nitride decorated Co3O4 composite exhibits significant sensing properties to ethanol which is 1.6 times higher than that of pure Co3O4, furthermore, the composite possesses high selectivity and stability towards ethanol detection

RACK1 promotes Bax oligomerization and dissociates the interaction of Bax and Bcl-XL

Bax, a member of Bcl-2 family, plays an essential role in apoptotic pathways induced by a number of apoptotic stimulus. In a search for new potential binding partners of Bax, we identified the receptor for activated C-kinase 1 (RACK1) by a yeast two-hybrid assay. We demonstrated that RACK1 interacts with Bax through its BH3 domain both in vitro and in vivo. Using immunostaining and immunoprecipitation experiments, we found that RACK1 colocalizes with Bax oligomers and promotes Bax oligomerization both in vitro and in vivo. Furthermore, we observed that RACK1 also interacts with Bcl-XL, an anti-apoptotic protein associated with Bax. Interestingly, the Bcl-XL/Bax interaction is decreased when RACK1 is overexpressed, but is increased when RACK1 is depleted, suggesting RACK1 disrupts the association of Bax and Bcl-XL. In addition, we found that overexpression of RACK1 promotes UV-induced apoptosis, while knocking down RACK] inhibits the effects. Together, these results indicate that RACK1 promotes apoptosis by promoting Bax oligomerization and dissociating the complex of Bax and Bcl-XL. (C) 2010 Elsevier Inc. All rights reserved