67 research outputs found
Compromiso con el trabajo y rendimiento en el trabajo: el papel moderador del apoyo organizacional percibido.
The present research was aim to examine whether the relationship between work engagement and objective task performance is moderated by perceived organizational support (POS). Based on the existing literature, perceived organizational support is hypothesized to strengthen the positive association between employees’ work engagement and their objective task performance. The hypotheses were tested on a sample of 1049 employees. Results of hierarchical regression analysis show that: (1) work engagement is positively related to objective task performance, and (2) the relationship between work engagement and objective task performance is moderated by POS, such that the positive relationship is more significant when POS higher than lower. In the end, theoretical and practical implications, and suggestions for future research are discussed.La presente investigación tuvo el objetivo de examinar si la relación entre compromiso con el trabajo y el rendimiento en los objetivos de las tareas está moderada por el apoyo perceptivo de la organización (APO). En base a la literatura existente, el apoyo percibido de la organización se hipotetiza que fortalece la asociación positiva entre el compromiso laboral de los empleados y su rendimiento en los objetivos de las tareas. Las hipótesis fueron comprobadas en una muestra de 1049 empleados. Los resultados del análisis de regresión jerárquico muestran que: (1) el compromiso en el trabajo está positivamente relacionado con el rendimiento en los objetivos de las tareas, y (2) la relación entre compromiso en el trabajo y el rendimiento en los objetivos de las tareas está moderado por el APO, de modo que la relación positiva es más significativa cuando el APO es mayor. Al final se discuten las implicaciones teóricas y prácticas, y las sugerencias para futuras investigaciones
What Drives the Trickle-Down Effect of Calling Orientation From Supervisors to Subordinates? The Perspective of Social Learning Theory
Despite an increase in research on calling orientation, few studies have investigated its antecedents. Drawing on social learning theory, we hypothesized that subordinates’ perceptions of their supervisor’s role modeling mediate the relationship between supervisor’s and subordinates’ calling orientations. Supervisor’s organizational status is supposed to augment the trickle-down process for calling orientation. We used multilevel modeling to test these hypotheses in a sample of 738 subordinates nested in 77 work teams in Chinese firm. We found that supervisor’s calling orientation was positively related to subordinate’s calling orientation and that the relationship was fully mediated by subordinates’ perceptions of role modeling. Additionally, the relationship between supervisor’s calling orientation and subordinates’ calling orientation via role modeling was moderated by supervisor’s organizational status at the second stage
Investigation of lipid metabolism dysregulation and the effects on immune microenvironments in pan-cancer using multiple omics data.
BACKGROUND: Lipid metabolism reprogramming is a hallmark for tumor which contributes to tumorigenesis and progression, but the commonality and difference of lipid metabolism among pan-cancer is not fully investigated. Increasing evidences suggest that the alterations in tumor metabolism, including metabolite abundance and accumulation of metabolic products, lead to local immunosuppression in the tumor microenvironment. An integrated analysis of lipid metabolism in cancers from different tissues using multiple omics data may provide novel insight into the understanding of tumorigenesis and progression.
RESULTS: Through systematic analysis of the multiple omics data from TCGA, we found that the most-widely altered lipid metabolism pathways in pan-cancer are fatty acid metabolism, arachidonic acid metabolism, cholesterol metabolism and PPAR signaling. Gene expression profiles of fatty acid metabolism show commonalities across pan-cancer, while the alteration in cholesterol metabolism and arachidonic acid metabolism differ with tissue origin, suggesting tissue specific lipid metabolism features in different tumor types. An integrated analysis of gene expression, DNA methylation and mutations revealed factors that regulate gene expression, including the differentially methylated sites and mutations of the lipid genes, as well as mutation and differential expression of the up-stream transcription factors for the lipid metabolism pathways. Correlation analysis of the proportion of immune cells in the tumor microenvironment and the expression of lipid metabolism genes revealed immune-related differentially expressed lipid metabolic genes, indicating the potential crosstalk between lipid metabolism and immune response. Genes related to lipid metabolism and immune response that are associated with poor prognosis were discovered including HMGCS2, GPX2 and CD36, which may provide clues for tumor biomarkers or therapeutic targets.
CONCLUSIONS: Our study provides an integrated analysis of lipid metabolism in pan-cancer, highlights the perturbation of key metabolism processes in tumorigenesis and clarificates the regulation mechanism of abnormal lipid metabolism and effects of lipid metabolism on tumor immune microenvironment. This study also provides new clues for biomarkers or therapeutic targets of lipid metabolism in tumors
A study of starch resources with high-amylose content from five Chinese mutant banana species
Investigation on staple crop starch of new species has been becoming the research focus of scholars at present. Based on this, the physicochemical properties and microstructural characteristics of starches isolated from Chinese mutant Musa acuminata Colla acuminata and double balbisiana (MA), Musa double acuminata cv. Pisang Mas (MAM), Musa acuminata cv. Pisang Awak (MAA), and Musa Basjoo Siebold (MBS), and Musa double acuminata and balbisiana-Prata (MAP) were investigated. Results exhibited that all starches exhibited high content of amylose (34.04–42.59%). According to the particle size, they were divided into medium (MA, MAM) (14.54–17.71 μm) and large (MAA, MBS, MAP) (23.01–23.82 μm) group. The medium group with A-type crystallization showed higher peak viscosity (PV), final viscosity, gel fracturability and gel hardness. For large group with B-type crystallization, the compact particle morphology, higher degree of crystallinity, short range order, gelatinization enthalpy, pasting temperature, lower porosity, water absorption capacity (WAC) and oil absorption capacity were found. In addition, the medium group with higher PV and gel hardness could be used as food thickening or gelling agents. The large group with higher Rc, short-range order, lower porosity and WAC could be potential to become raw material for resistant starch. All results showed the amylose content, had significant effect on the microstructure and physicochemical properties of starch samples. Outcomes in this investigation might provide a basis of theoretical application for industrial food production
Antimicrobial concrete for smart and durable infrastructures: a review
YesConcrete structures in sewer systems, marine engineering, underground engineering and other humid environments are easily subjected to microbial attachment, colonization and, eventually, deterioration. With careful selection and treatment, some additives including inorganic and organic antimicrobial agents were found to be able to endow concrete with excellent antimicrobial performance. This paper reviews various types of antimicrobial concrete fabricated with different types of antimicrobial agents. The classification and methods of applying antimicrobial agents into concrete are briefly introduced. The antimicrobial and mechanical properties as well as mass/weight loss of concrete incorporating antimicrobial agents are summarised. Applications reported in this field are presented and future research opportunities and challenges of antimicrobial concrete are also discussed in this review.National Science Foundation of China (51908103 and 51978127), China Postdoctoral Science Foundation (2019M651116
The managerial antecedent and behavioral consequence of subordinates’ calling orientation: an experimental and survey study
Abstract Research in calling has increased in recent years, yet the lack of attention on the managerial antecedents and prosocial behavioral outcome of calling orientation presents key challenges to meet the needs of the organizational management. Based on the social impact theory, this study examined the predicting effects of a team leader’s transformational leadership on followers’ calling orientation, and the effects of team members’ calling orientation on their helping behaviors at work. The experimental study and the survey were conducted to test the hypotheses. The results showed that a leader’s transformational leadership was positively related to followers’ calling orientation. A leader’s organizational status moderated the relationship between a leader’s transformational leadership and followers’ calling orientation. Followers’ calling orientation was positively related to their helping behaviors at work. The results provide important implications for cultivating employees’ calling orientation in the workplace
Guanxi HRM Practice and Employees’ Occupational Well-Being in China: A Multi-Level Psychological Process
Chinese employees may experience and respond to guanxi human resource management (HRM) practice (e.g., recruiting, selecting, inducting and appraising employees based on personal relationships). Little has been done to examine the linkage between guanxi HRM practice and employees’ occupational well-being. This study investigates the psychological process of how guanxi HRM practice affects employees’ occupational well-being. The theoretical model of this study proposes that employee psychological safety mediates the relationship between guanxi HRM practice and occupational well-being, while collectivistic team culture moderates the relationship between guanxi HRM practice and psychological safety. Multi-level data from 297 employees nested within 42 teams support all hypotheses. This study reveals the cross-level effects of guanxi HRM practice and providing practical suggestions for future research on psychologically safe and healthy work environments
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