318 research outputs found
Corporate social responsibility and its impact on the corporate decision-making process for university undergraduate research fellows
- Author
- Publication venue
- Texas A&M University
- Publication date
- 22/02/2013
- Field of study
Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to [email protected], referencing the URI of the item.Includes bibliographical references (leaves 50-53).This study seeks to answer the question, "How does corporate social responsibility (CSR) influence corporate decision making?" It does so in two steps. The first step is the building of a theoretical framework in order to understand the many, vastly different academic theories on CSR. The framework that exists groups thoughts on CSR into three categories, which are as follows: normative stakeholder theory, shareholder wealth maximization theory, and strategic stakeholder theory. Proponents of "normative stakeholder theory" argue that, as a product of society, the corporation should be held accountable to the demands of society, as seen through their various stakeholders. Believers of "shareholder wealth maximization theory" argue that societal utility is maximized as each unit of society seeks to maximize his or her own utility and, therefore, believe that the principles of CSR dictate that the corporation should be held accountable solely to its shareholders, which are the fundamental owners of the corporation. "Strategic stakeholder theory" is a metaphoric bridge between its two counterparts. Strategic stakeholder theory recognizes that a tradeoff exists for the firm between the immediate wishes of all stakeholders. For the long-term profitability of the firm, strategic stakeholder theory recognizes that both financial and non-financial stakeholders must be acknowledged. The recognition of this tradeoff leads to the second half of this study. The second part of this study picks up the debate on the relationship between CSR and firm financial performance. It is argued that this relationship is the underlying assumption that separates shareholder wealth maximization theory, which believes that a firm benefits society by seeking its own ends, and normative stakeholder theory, which believes that a firm does not benefit society by seeking profits. To add to the base of knowledge on this topic, a difference of means test is performed on companies that are in the DSI 400, a socially responsive stock index, against companies that are not in the DSI 400. A significant difference was discovered in the attributes measured. It is concluded that the DSI 400 serves as a valid proxy for CSR and further research using the DSI 400 is encouraged
Corporate social responsibility and its impact on the corporate decision-making process for university undergraduate research fellows
- Author
- Publication venue
- Texas A&M University
- Publication date
- 22/02/2013
- Field of study
Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to [email protected], referencing the URI of the item.Includes bibliographical references (leaves 50-53).This study seeks to answer the question, "How does corporate social responsibility (CSR) influence corporate decision making?" It does so in two steps. The first step is the building of a theoretical framework in order to understand the many, vastly different academic theories on CSR. The framework that exists groups thoughts on CSR into three categories, which are as follows: normative stakeholder theory, shareholder wealth maximization theory, and strategic stakeholder theory. Proponents of "normative stakeholder theory" argue that, as a product of society, the corporation should be held accountable to the demands of society, as seen through their various stakeholders. Believers of "shareholder wealth maximization theory" argue that societal utility is maximized as each unit of society seeks to maximize his or her own utility and, therefore, believe that the principles of CSR dictate that the corporation should be held accountable solely to its shareholders, which are the fundamental owners of the corporation. "Strategic stakeholder theory" is a metaphoric bridge between its two counterparts. Strategic stakeholder theory recognizes that a tradeoff exists for the firm between the immediate wishes of all stakeholders. For the long-term profitability of the firm, strategic stakeholder theory recognizes that both financial and non-financial stakeholders must be acknowledged. The recognition of this tradeoff leads to the second half of this study. The second part of this study picks up the debate on the relationship between CSR and firm financial performance. It is argued that this relationship is the underlying assumption that separates shareholder wealth maximization theory, which believes that a firm benefits society by seeking its own ends, and normative stakeholder theory, which believes that a firm does not benefit society by seeking profits. To add to the base of knowledge on this topic, a difference of means test is performed on companies that are in the DSI 400, a socially responsive stock index, against companies that are not in the DSI 400. A significant difference was discovered in the attributes measured. It is concluded that the DSI 400 serves as a valid proxy for CSR and further research using the DSI 400 is encouraged
Reconsidering frameworks of Alzheimerβs dementia when assessing psychosocial outcomes
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2019
- Field of study
The purpose of this introductory article to the special issue on psychosocial outcome measures in Alzheimerβs & Dementia: Translational Research & Clinical Interventions is to outline new frameworks to more effectively capture and measure the full range of how people living with Alzheimerβs dementia and their family caregivers experience the disease process. Specifically, we consider the strengths and weaknesses of alternative perspectives, including personβcentered, strengthβbased, and resilienceβfocused approaches that may complement and extend the dominant deficit paradigm to reflect the entirety of the dementia experience. Our aim is to encourage innovative methods to measure psychosocial aspects of Alzheimerβs dementia and caregiving that have not yet received sufficient attention, including resources (e.g., services and supports) and positive caregiver and care recipient outcomes (e.g., positive mood and adaptation).Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/152840/1/trc2jtrci201902008.pd
A Chemical Screen Probing the Relationship between Mitochondrial Content and Cell Size
- Author
- Toshimori Kitami
- David J. Logan
- Joseph Negri
- Thomas Hasaka
- Nicola J. Tolliday
- Anne E. Carpenter
- Bruce M. Spiegelman
- Vamsi K. Mootha
- Yidong Bai
- M Kleiber
- VK Mootha
- H Zong
- H Wu
- E Nisoli
- JW Posakony
- P Puigserver
- Z Wu
- J Lin
- JM Huss
- SN Schreiber
- MJ Evans
- CA Virbasius
- KL LaMarco
- DP Kelly
- VK Mootha
- BK Wagner
- Z Arany
- MW Karaman
- J Bain
- GL Wright
- P Echave
- F Li
- AE Carpenter
- TR Jones
- KP Seiler
- GE Truett
- M Wu
- AM McGehee
- MD Abramoff
- Publication venue
- Public Library of Science
- Publication date
- 01/01/1992
- Field of study
The cellular content of mitochondria changes dynamically during development and in response to external stimuli, but the underlying mechanisms remain obscure. To systematically identify molecular probes and pathways that control mitochondrial abundance, we developed a high-throughput imaging assay that tracks both the per cell mitochondrial content and the cell size in confluent human umbilical vein endothelial cells. We screened 28,786 small molecules and observed that hundreds of small molecules are capable of increasing or decreasing the cellular content of mitochondria in a manner proportionate to cell size, revealing stereotyped control of these parameters. However, only a handful of compounds dissociate this relationship. We focus on one such compound, BRD6897, and demonstrate through secondary assays that it increases the cellular content of mitochondria as evidenced by fluorescence microscopy, mitochondrial protein content, and respiration, even after rigorous correction for cell size, cell volume, or total protein content. BRD6897 increases uncoupled respiration 1.6-fold in two different, non-dividing cell types. Based on electron microscopy, BRD6897 does not alter the percent of cytoplasmic area occupied by mitochondria, but instead, induces a striking increase in the electron density of existing mitochondria. The mechanism is independent of known transcriptional programs and is likely to be related to a blockade in the turnover of mitochondrial proteins. At present the molecular target of BRD6897 remains to be elucidated, but if identified, could reveal an important additional mechanism that governs mitochondrial biogenesis and turnover
Single hadron response measurement and calorimeter jet energy scale uncertainty with the ATLAS detector at the LHC
- Author
- A. A. Abdelalim
- A. A. Carter
- A. A. Grillo
- A. A. Komar
- A. A. Minaenko
- A. A. Nepomuceno
- A. A. Snesarev
- A. A. Solodkov
- A. Abdesselam
- A. Ahmad
- A. Akiyama
- A. Aloisio
- A. Alonso
- A. Amorim
- A. Andreazza
- A. Angerami
- A. Anisenkov
- A. Annovi
- A. Antonaki
- A. Antonov
- A. Artamonov
- A. Astbury
- A. Astvatsatourov
- A. B. Fenyuk
- A. B. Lazarev
- A. Bangert
- A. Barashkou
- A. Barbaro Galtieri
- A. Baroncelli
- A. Battaglia
- A. Beddall
- A. Belloni
- A. Bertin
- A. Bingul
- A. Blondel
- A. Bocci
- A. Bogdanchikov
- A. Bogouch
- A. Borisov
- A. Boveia
- A. Braem
- A. Brandt
- A. Bruni
- A. C. KΓΆnig
- A. C. Martyniuk
- A. C. Schaffer
- A. Canepa
- A. Catinaccio
- A. Cattai
- A. Cerri
- A. Chafaq
- A. Cheplakov
- A. Chilingarov
- A. Christov
- A. Ciocio
- A. Clark
- A. Coccaro
- A. Cortes-Gonzalez
- A. D. Doxiadis
- A. D. Hawkins
- A. D. Hershenhorn
- A. D. Pilkington
- A. De Salvo
- A. De Santo
- A. DellβAcqua
- A. Dewhurst
- A. Di Ciaccio
- A. Di Girolamo
- A. Di Mattia
- A. Di Simone
- A. Do Valle Wemans
- A. Doria
- A. Dos Anjos
- A. Dotti
- A. Dudarev
- A. DβOrazio
- A. E. Barton
- A. E. Kiryunin
- A. Engl
- A. Eppig
- A. Ereditato
- A. F. Saavedra
- A. Farbin
- A. Farilla
- A. Favareto
- A. Ferrari
- A. Ferrer
- A. Ferretto Parodi
- A. Filippas
- A. FilipΔiΔ
- A. Firan
- A. Floderus
- A. Formica
- A. Forti
- A. Foussat
- A. G. Buckley
- A. G. Goussiou
- A. G. Kholodenko
- A. G. Myagkov
- A. G. Olchevski
- A. G. Schamov
- A. Gaponenko
- A. Gemmell
- A. Gershon
- A. Gibson
- A. Glazov
- A. Gomes
- A. Gonidec
- A. GoriΕ‘ek
- A. Guida
- A. Gupta
- A. Haas
- A. Hamilton
- A. Harvey
- A. Henrichs
- A. Hoecker
- A. Hoummada
- A. Huettmann
- A. I. Etienvre
- A. I. Kononov
- A. I. Mincer
- A. Irles Quiles
- A. Ishikawa
- A. J. Armbruster
- A. J. Barr
- A. J. Beddall
- A. J. Fowler
- A. J. Lankford
- A. J. Lowe
- A. J. Martin
- A. J. Tanasijczuk
- A. Jantsch
- A. Jeremie
- A. Juste Rozas
- A. K. Ciftci
- A. K. Morley
- A. Kaczmarska
- A. Kapliy
- A. Kasmi
- A. Kastanas
- A. Khanov
- A. Khodinov
- A. Khomich
- A. Khoroshilov
- A. Kiryunin
- A. Klier
- A. Klimentov
- A. Knue
- A. Kootz
- A. Korn
- A. Korol
- A. Kotwal
- A. Koutsman
- A. Krasznahorkay
- A. Kreisel
- A. Kruth
- A. Kugel
- A. Kupco
- A. L. Maslennikov
- A. L. Read
- A. La Rosa
- A. Larner
- A. Leger
- A. Leung Fook Cheong
- A. Lewis
- A. Limosani
- A. Lipniacka
- A. Lister
- A. Lleres
- A. Loginov
- A. Lounis
- A. Lucotte
- A. Ludwig
- A. M. Bach
- A. M. Castaneda Hernandez
- A. M. Cooper-Sarkar
- A. M. Henriques Correia
- A. M. Kiver
- A. M. Leyko
- A. M. Litke
- A. M. Moisseev
- A. M. Nairz
- A. M. Rahimi
- A. M. Zaitsev
- A. Macchiolo
- A. Maio
- A. Manabe
- A. Mann
- A. Manousakis-Katsikakis
- A. Manz
- A. Mapelli
- A. Marin
- A. Marzin
- A. Mastroberardino
- A. Mayne
- A. McCarn
- A. Meade
- A. Mehta
- A. Mengarelli
- A. Messina
- A. Milov
- A. Misiejuk
- A. Moraes
- A. Muir
- A. N. Karyukhin
- A. N. Sisakyan
- A. Nagarkar
- A. Napier
- A. Negri
- A. Nelson
- A. Neusiedl
- A. Nikiforov
- A. Nisati
- A. Ochi
- A. Oh
- A. Olariu
- A. Olszewski
- A. Onofre
- A. Ouraou
- A. Ovcharova
- A. P. Colijn
- A. P. Vorobiev
- A. Pacheco Pages
- A. Palma
- A. Papadelis
- A. Paramonov
- A. Passeri
- A. Penson
- A. Perus
- A. Petridis
- A. Phan
- A. Pinder
- A. Poblaguev
- A. Policicchio
- A. Polini
- A. Poppleton
- A. Pranko
- A. Quadt
- A. R. Davison
- A. R. Gillman
- A. R. Stradling
- A. R. Weidberg
- A. Redelbach
- A. Reichold
- A. Reinsch
- A. Renaud
- A. Richards
- A. Rimoldi
- A. Robichaud-Veronneau
- A. Robson
- A. Roe
- A. Romaniouk
- A. Rose
- A. Rozanov
- A. Ruiz-Martinez
- A. S. Cerqueira
- A. S. Chisholm
- A. S. Kozhin
- A. S. Mete
- A. S. Randle-Conde
- A. S. Thompson
- A. Salamon
- A. Salnikov
- A. Salvucci
- A. Salzburger
- A. Sanchez
- A. Sansoni
- A. Sbrizzi
- A. Schwartzman
- A. SchΓΆning
- A. Seiden
- A. Sfyrla
- A. Shibata
- A. Shmeleva
- A. Sidoti
- A. Sircar
- A. Soffer
- A. Soukharev
- A. Staude
- A. Straessner
- A. Strandlie
- A. Succurro
- A. T. Doyle
- A. T. H. Arce
- A. T. Watson
- A. T. Waugh
- A. Taffard
- A. Talyshev
- A. Tonoyan
- A. Tricoli
- A. Trivedi
- A. Trzupek
- A. Tua
- A. Tudorache
- A. Tykhonov
- A. Undrus
- A. V. Akimov
- A. V. Ivashin
- A. V. Larionov
- A. V. Pleskach
- A. Vaniachine
- A. Vartapetian
- A. Ventura
- A. Vest
- A. Vogel
- A. Warburton
- A. White
- A. Wildauer
- A. Wilson
- A. Yamamoto
- A. Yurkewicz
- A. Zaytsev
- A. Zemla
- A. Zhemchugov
- A. Zoccoli
- A. Zsenei
- A.-E. Nuncio-Quiroz
- ATLAS Collaboration
- ATLAS Collaboration
- ATLAS Collaboration
- ATLAS Collaboration
- ATLAS Collaboration
- ATLAS Collaboration
- ATLAS Collaboration
- ATLAS Collaboration
- B. A. Dolgoshein
- B. A. Petersen
- B. A. Schumm
- B. Abbott
- B. Abi
- B. Alvarez Gonzalez
- B. Aubert
- B. Brau
- B. Brelier
- B. Budick
- B. Butler
- B. C. LeGeyt
- B. C. Smith
- B. Caron
- B. Chapleau
- B. Clement
- B. D. Cooper
- B. De Lotto
- B. Demirkoz
- B. DeWilde
- B. Di Girolamo
- B. Di Micco
- B. Dowler
- B. E. Cox
- B. Epp
- B. Esposito
- B. Fatholahzadeh
- B. G. Pope
- B. Gaur
- B. Giacobbe
- B. Gibbard
- B. Gorini
- B. Gosdzik
- B. Guo
- B. H. Samset
- B. H. Smart
- B. Heinemann
- B. J. Gallop
- B. J. OβBrien
- B. Jackson
- B. K. Gjelsten
- B. K. Wosiek
- B. Kaplan
- B. Laforge
- B. Lemmer
- B. Lenzi
- B. Li
- B. Liberti
- B. Lund-Jensen
- B. Lundberg
- B. M. Barnett
- B. M. Hawes
- B. M. M. Allbrooke
- B. M. Salvachua Ferrando
- B. M. Waugh
- B. M. Wynne
- B. Malaescu
- B. Mansoulie
- B. Martin
- B. Martin
- B. MartinΒ ditΒ Latour
- B. MaΔek
- B. Meirose
- B. Mindur
- B. Nicquevert
- B. Nordkvist
- B. Osculati
- B. P. KerΕ‘evan
- B. Panes
- B. Penning
- B. Pinto
- B. R. Ko
- B. R. Mellado Garcia
- B. Radics
- B. Resende
- B. Ruckert
- B. S. Acharya
- B. Sellden
- B. Simmons
- B. Sopko
- B. Spurlock
- B. Stelzer
- B. Stugu
- B. Szeless
- B. T. King
- B. Toczek
- B. Toggerson
- B. TrocmΓ©
- B. Vachon
- B. Wrona
- B. Yabsley
- B. Zabinski
- B. Zhou
- B. Γ sman
- C. A. Chavez Barajas
- C. A. Edwards
- C. A. Jung
- C. A. Solans
- C. Alexa
- C. Amelung
- C. Anastopoulos
- C. Arnault
- C. Ay
- C. B. Gwilliam
- C. Bacci
- C. Belanger-Champagne
- C. Benchouk
- C. Bernius
- C. Bertella
- C. Bini
- C. Biscarat
- C. Blocker
- C. Bohm
- C. Borer
- C. Bourdarios
- C. Bromberg
- C. C. Ohm
- C. Caramarcu
- C. Caso
- C. Chen
- C. Ciocca
- C. Clement
- C. Cojocaru
- C. Collard
- C. Collins-Tooth
- C. Conta
- C. Cowden
- C. Cuenca Almenar
- C. Cuthbert
- C. D. Burgard
- C. Da Via
- C. Dallapiccola
- C. Debenedetti
- C. Del Papa
- C. Deluca
- C. DeΒ La Taille
- C. Dionisi
- C. Doglioni
- C. Driouichi
- C. Escobar
- C. F. Anders
- C. Fabre
- C. Feng
- C. Ferretti
- C. Fukunaga
- C. G. Lester
- C. G. Zhu
- C. Gabaldon
- C. Galea
- C. GarcΓa
- C. Gatti
- C. Gay
- C. Gemme
- C. Geweniger
- C. Glasman
- C. Goeringer
- C. Goy
- C. Guicheney
- C. Guyot
- C. Gwenlan
- C. GΓΆssling
- C. Haber
- C. Handel
- C. Heller
- C. Helsens
- C. Hensel
- C. Horn
- C. Isaksson
- C. Issever
- C. J. Curtis
- C. J. Kenney
- C. J. Oram
- C. J. Potter
- C. Joram
- C. Kourkoumelis
- C. Kummer
- C. L. Lampen
- C. Lacasta
- C. Lange
- C. Lapoire
- C. Lasseur
- C. Le Maner
- C. Lebel
- C. Leggett
- C. Leroy
- C. Limbach
- C. Liu
- C. Luci
- C. M. Buttar
- C. M. Hawkes
- C. M. Hernandez
- C. Maiani
- C. Maidantchik
- C. Malone
- C. Mattravers
- C. Melachrinos
- C. Menot
- C. Meroni
- C. Meyer
- C. Meyer
- C. Mills
- C. Mora Herrera
- C. N. Booth
- C. N. P. Gee
- C. Omachi
- C. Oropeza Barrera
- C. Osuna
- C. P. Bee
- C. P. Buszello
- C. P. Marino
- C. P. Paleari
- C. P. Ward
- C. Padilla Aranda
- C. Petridou
- C. Pizio
- C. Posch
- C. R. Boddy
- C. R. Royon
- C. Rembser
- C. Roda
- C. Rudolph
- C. Ruwiedel
- C. Sandoval
- C. Santamarina Rios
- C. Santoni
- C. Sbarra
- C. Schiavi
- C. Schmitt
- C. Schroeder
- C. Schwanenberger
- C. Serfon
- C. Stanescu
- C. Suhr
- C. T. Potter
- C. Taylor
- C. Topfel
- C. Troncon
- C. Tsarouchas
- C. Vellidis
- C. W. Loh
- C. Wang
- C. Weiser
- C. Weydert
- C. Wiglesworth
- C. Wright
- C. Xu
- C. Young
- C. Zeitnitz
- C. Zendler
- C.-M. Cuciuc
- Ch. Geich-Gimbel
- CMS Collaboration
- D. A. A. Geerts
- D. A. Forbush
- D. A. Maximov
- D. A. Milstead
- D. A. Scannicchio
- D. A. Soh
- D. Arutinov
- D. Axen
- D. Banfi
- D. Barberis
- D. Benchekroun
- D. Berge
- D. Boscherini
- D. Botterill
- D. Boumediene
- D. Britton
- D. Bruncko
- D. C. Bailey
- D. C. OβNeil
- D. Caforio
- D. Calvet
- D. Cameron
- D. Capriotti
- D. Casadei
- D. Cauz
- D. Cavalli
- D. Chakraborty
- D. Chromek-Burckhart
- D. Cinca
- D. Costanzo
- D. CΓ΄tΓ©
- D. Dannheim
- D. De Pedis
- D. della Volpe
- D. Derendarz
- D. Dobos
- D. E. FerreiraΒ deΒ Lima
- D. Emeliyanov
- D. Eriksson
- D. Errede
- D. Evangelakou
- D. F. Howell
- D. Fassouliotis
- D. Fellmann
- D. Ferrere
- D. Fortin
- D. Fournier
- D. Francis
- D. Froidevaux
- D. G. Charlton
- D. G. Underwood
- D. Gillberg
- D. Giugni
- D. Goujdami
- D. Guest
- D. H. Saxon
- D. Hall
- D. Harper
- D. Hauff
- D. Hawkins
- D. Hayden
- D. Hellmich
- D. Hill
- D. Hirschbuehl
- D. Hoffmann
- D. Iliadis
- D. Joffe
- D. K. Jana
- D. Kar
- D. Kharchenko
- D. Kisielewska
- D. Kuhn
- D. L. Adams
- D. Lacour
- D. Lellouch
- D. Levin
- D. Lissauer
- D. Liu
- D. Lopez Mateos
- D. Ludwig
- D. Lumb
- D. Lynn
- D. M. Gingrich
- D. M. Pomarede
- D. M. Rebuzzi
- D. M. Seliverstov
- D. M. Strom
- D. Malon
- D. Milstein
- D. Moreno
- D. Muenstermann
- D. O. Savu
- D. Oliveira Damazio
- D. Olivito
- D. Orestano
- D. P. Benjamin
- D. P. C. Sankey
- D. Pallin
- D. Pantea
- D. Paredes Hernandez
- D. Petschull
- D. Pomeroy
- D. Price
- D. Prieur
- D. R. Hadley
- D. R. Quarrie
- D. R. Rust
- D. R. Tovey
- D. Rahm
- D. Robinson
- D. RodaΒ DosΒ Santos
- D. Rodriguez
- D. Rousseau
- D. S. Damiani
- D. S. Popovic
- D. Salihagic
- D. Salvatore
- D. Sampsonidis
- D. Schaile
- D. Scheirich
- D. Schouten
- D. Sherman
- D. Short
- D. Silverstein
- D. Smith
- D. Su
- D. T. Pignotti
- D. Ta
- D. Tardif
- D. Tsionou
- D. Tsybychev
- D. Turecek
- D. Urbaniec
- D. V. Dedovich
- D. vanΒ der Ster
- D. Varouchas
- D. Ventura
- D. Vladoiu
- D. W. Miller
- D. Wendland
- D. Whiteson
- D. Whittington
- D. Wicke
- D. Xu
- D. Y. Bardin
- D. Yu
- D. Zerwas
- D. Zhang
- D. Zieminska
- Dj. Sijacki
- E. A. Ouellette
- E. A. Starchenko
- E. Abat
- E. Acerbi
- E. Arik
- E. Auge
- E. B. Diehl
- E. B. F. G. Knoops
- E. B. Klinkby
- E. Badescu
- E. Banas
- E. Benhar Noccioli
- E. Bergeaas Kuutmann
- E. Berglund
- E. Brodet
- E. Busato
- E. Castaneda-Miranda
- E. Chareyre
- E. Cheu
- E. Cogneras
- E. Coniavitis
- E. Davies
- E. Dawe
- E. Devetak
- E. Dobson
- E. Duchovni
- E. Eisenhandler
- E. Ertel
- E. Etzion
- E. Fullana Torregrosa
- E. G. Tskhadadze
- E. Gorini
- E. Gornicki
- E. Graziani
- E. Gross
- E. Hazen
- E. HigΓ³n-Rodriguez
- E. Hines
- E. I. Rosenberg
- E. J. Feng
- E. J. Gallas
- E. J. W. Moyse
- E. Jankowski
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- E. Kladiva
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- E. Koffeman
- E. L. Barberio
- E. Ladygin
- E. Laisne
- E. Lancon
- E. Le Guirriec
- E. Le Menedeu
- E. Lipeles
- E. Lobodzinska
- E. Lund
- E. Lytken
- E. Magradze
- E. Mazzoni
- E. Meoni
- E. Monnier
- E. Mountricha
- E. Musto
- E. N. Gazis
- E. N. May
- E. N. Thompson
- E. Nebot
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- E. Oliver Garcia
- E. Paganis
- E. Panagiotopoulou
- E. Pasqualucci
- E. Perez Codina
- E. Petit
- E. Petrolo
- E. Piccaro
- E. Ptacek
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- E. Reinherz-Aronis
- E. Richter-Was
- E. Rizvi
- E. Romero Adam
- E. Ros
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- E. S. Kuwertz
- E. Sarkisyan-Grinbaum
- E. Sauvan
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- E. Sedykh
- E. Segura
- E. Shabalina
- E. Shulga
- E. Soldatov
- E. Solfaroli Camillocci
- E. Stanecka
- E. Strauss
- E. Tassi
- E. Thomson
- E. Torrence
- E. TorrΓ³ Pastor
- E. Turlay
- E. V. Bouhova-Thacker
- E. V. Korolkova
- E. Valladolid Gallego
- E. vanΒ der Kraaij
- E. vanΒ der Poel
- E. Vilucchi
- E. Vinek
- E. von Toerne
- E. W. Hughes
- E. W. Varnes
- E. Williams
- E. Wulf
- E.-E. Kluge
- F. Ahles
- F. Alessandria
- F. Anghinolfi
- F. Anulli
- F. Barreiro
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- F. Bellina
- F. Berghaus
- F. Bertinelli
- F. Bertolucci
- F. Broggi
- F. Bucci
- F. Butin
- F. Canelli
- F. Cataneo
- F. Ceradini
- F. Cerutti
- F. Cevenini
- F. Conventi
- F. Corriveau
- F. Crescioli
- F. Derue
- F. Diblen
- F. Dittus
- F. Djama
- F. Dudziak
- F. Dydak
- F. E. Taylor
- F. Ellinghaus
- F. Etienne
- F. F. Martin
- F. Fiedler
- F. Filthaut
- F. Friedrich
- F. G. Oakham
- F. Garberson
- F. Gianotti
- F. Grancagnolo
- F. Hahn
- F. Hartjes
- F. Henry-Couannier
- F. Hirsch
- F. Hubaut
- F. Huegging
- F. J. Tique Aires Viegas
- F. J. Wickens
- F. K. Loebinger
- F. K. Martens
- F. Khalil-zada
- F. Koetsveld
- F. Kohn
- F. Krejci
- F. Lacava
- F. Lanni
- F. Ledroit-Guillon
- F. Legger
- F. Linde
- F. Lo Sterzo
- F. Lu
- F. Luehring
- F. M. Brochu
- F. M. Giorgi
- F. Malek
- F. Marchese
- F. Marroquim
- F. Marzano
- F. Monticelli
- F. Mueller
- F. Niedercorn
- F. Ould-Saada
- F. Paige
- F. Parodi
- F. Pastore
- F. Petrucci
- F. Podlyski
- F. Polci
- F. Prokoshin
- F. Quinonez
- F. Ragusa
- F. Rauscher
- F. Rizatdinova
- F. Ruggieri
- F. RΓΌhr
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- F. Safai Tehrani
- F. Salvatore
- F. Sarri
- F. Seifert
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- F. Tarrade
- F. Tian
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- F. Varela Rodriguez
- F. Vazeille
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- F. Vives Vaque
- F. Wicek
- F. Winklmeier
- Fr. Pastore
- G. A. Chelkov
- G. A. Hare
- G. A. Popeneciu
- G. A. Rosenbaum
- G. A. Stewart
- G. Aad
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- G. Akimoto
- G. Alexander
- G. Alexandre
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- G. Anders
- G. Arabidze
- G. Artoni
- G. Avolio
- G. Azuelos
- G. Baccaglioni
- G. Barone
- G. Bella
- G. Blanchot
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- G. Brandt
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- G. Brown
- G. Bruni
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- G. Carlino
- G. Cataldi
- G. Cattani
- G. Chiefari
- G. Chiodini
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- G. D. Kekelidze
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- G. Eigen
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- G. Fischer
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- G. Gagliardi
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- G. Iacobucci
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- G. J. Bobbink
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- G. Kasieczka
- G. Kawamura
- G. Khoriauli
- G. Kramberger
- G. L. Darlea
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- G. Lenzen
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- G. Marchiori
- G. Massaro
- G. Mchedlidze
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- G. Mirabelli
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- G. N. Taylor
- G. Nanava
- G. Navarro
- G. Negri
- G. Nunes Hanninger
- G. OteroΒ yΒ Garzon
- G. P. Tappern
- G. Palacino
- G. Piacquadio
- G. Polesello
- G. Poulard
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- G. Rivoltella
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- G. Rudolph
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- G. Sauvage
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- G. Sedov
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- G. Sellers
- G. Siragusa
- G. Spigo
- G. Stavropoulos
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- G. Stoicea
- G. Susinno
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- G. Unal
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- G. Vandoni
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- G. Volpi
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- G. Zobernig
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- H. von Radziewski
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- I. Hinchliffe
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- I. M. Trigger
- I. MandiΔ
- I. Massa
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- I. Nakano
- I. Nikolic-Audit
- I. Nomidis
- I. Orlov
- I. P. Duerdoth
- I. R. Boyko
- I. Reisinger
- I. Riu
- I. Roth
- I. Rubinskiy
- I. Sadeh
- I. Satsounkevitch
- I. Stekl
- I. Stumer
- I. Sykora
- I. Torchiani
- I. Turk Cakir
- I. Ueda
- I. van Vulpen
- I. Vichou
- I. Vivarelli
- I. Vukotic
- I. Wilhelm
- I. Wingerter-Seez
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- J. B. De VivieΒ DeΒ Regie
- J. B. Hansen
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- J. Beringer
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- L. A. Skinnari
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- L. Labarga
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- L. March
- L. Masetti
- L. Mendoza Navas
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- L. Morvaj
- L. N. Smirnova
- L. Nicolas
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- L. Roos
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- M. A. B. do Vale
- M. A. Baak
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- M. A. Diaz
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- M. Abolins
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- M. Ahsan
- M. Aleksa
- M. Alhroob
- M. Aliev
- M. Aliyev
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- M. Arik
- M. Aurousseau
- M. Backes
- M. Backhaus
- M. Barbero
- M. Barisonzi
- M. Battistin
- M. Beckingham
- M. Begel
- M. Beimforde
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- M. Biglietti
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- M. Boehler
- M. Bona
- M. Bondioli
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- M. Cambiaghi
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- M. Ciubancan
- M. Cobal
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- M. Dobson
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- M. Donega
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- M. Dunford
- M. Dwuznik
- M. DΓΌhrssen
- M. DΓΌren
- M. DβOnofrio
- M. E. Sevior
- M. El Kacimi
- M. Ellert
- M. Elsing
- M. Ernst
- M. Escalier
- M. F. Tripiana
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- M. Garcia-Sciveres
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- M. Goebel
- M. Gosselink
- M. Gouighri
- M. Groh
- M. H. Genest
- M. Hamer
- M. Hance
- M. Hatch
- M. Hauschild
- M. Havranek
- M. He
- M. Heller
- M. Henke
- M. Hirose
- M. Hohlfeld
- M. Holder
- M. Huhtinen
- M. Hurwitz
- M. I. Besana
- M. I. Gostkin
- M. I. Pedraza Morales
- M. I. Scherzer
- M. Ibbotson
- M. Ikeno
- M. Imori
- M. Iodice
- M. Ishino
- M. J. Costa
- M. J. Fisher
- M. J. Flowerdew
- M. J. KotamΓ€ki
- M. J. Losty
- M. J. Oreglia
- M. J. Price
- M. J. Schultens
- M. J. Shochet
- M. J. Tibbetts
- M. J. White
- M. J. Woudstra
- M. Janus
- M. Jimenez Belenguer
- M. Johansen
- M. K. Jha
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- M. Kaneda
- M. Karagounis
- M. Karagoz
- M. Karnevskiy
- M. Kataoka
- M. Keil
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- M. Khakzad
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- M. Kurata
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- M. L. Gonzalez Silva
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- M. Lassnig
- M. Lefebvre
- M. Legendre
- M. Lehmacher
- M. Leltchouk
- M. Leyton
- M. Lichtnecker
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- M. Livan
- M. Lokajicek
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- M. Marcisovsky
- M. Martinez
- M. Marx
- M. Mathes
- M. Mazur
- M. Mazzanti
- M. Mechtel
- M. Medinnis
- M. Mikestikova
- M. MikuΕΎ
- M. Mineev
- M. MiΓ±ano Moya
- M. Moreno LlΓ‘cer
- M. Morgenstern
- M. Morii
- M. Mosidze
- M. Mudrinic
- M. Myska
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- M. Nessi
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- M. Nozaki
- M. Olcese
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- M. Pinamonti
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- M. Przybycien
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- M. R. Hoeferkamp
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- M. Rescigno
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- M. Sandhoff
- M. Scarcella
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- M. Schram
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- M. Shamim
- M. Shapiro
- M. Shimojima
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- M. Smizanska
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- M. Solar
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- M. T. PΓ©rez GarcΓa-EstaΓ±
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- M. Tasevsky
- M. Tatarkhanov
- M. Teinturier
- M. Teixeira Dias Castanheira
- M. Testa
- M. Thioye
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- M. Tomoto
- M. Trottier-McDonald
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- M. Tsiakiris
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- M. Vlasak
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- M. Vos
- M. Vranjes Milosavljevic
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- M. W. Krasny
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- M. Warsinsky
- M. Weber
- M. Wen
- M. Werner
- M. Werth
- M. Wessels
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- M. Wright
- M. Xiao
- M. Y. Kazarinov
- M. Yamada
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- M. Zeller
- M. Zeman
- M. Ziolkowski
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- N. A. Styles
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- N. Anjos
- N. B. Sinev
- N. Barlow
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- N. C. Ryder
- N. D. Topilin
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- N. Hod
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- P. J. Clark
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- S. Mohrdieck-MΓΆck
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- S. Nektarijevic
- S. Nelson
- S. Nemecek
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- S. Oda
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- S. Snyder
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- S. Stern
- S. Stonjek
- S. Strandberg
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- S. Tanaka
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- S. V. Chekulaev
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- T. A. MΓΌller
- T. Adye
- T. Akdogan
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- T. Andeen
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- T. B. Sjursen
- T. Bain
- T. Barber
- T. Barillari
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- T. Burgess
- T. C. Meyer
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- T. Carli
- T. Chen
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- T. Costin
- T. Cuhadar Donszelmann
- T. Dai
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- T. Del Prete
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- T. Doherty
- T. Dohmae
- T. Ehrich
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- T. Greenshaw
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- T. Hayakawa
- T. Hayashi
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- T. Ince
- T. J. Brodbeck
- T. J. Jones
- T. J. Khoo
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- T. K. Nelson
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- T. Kanno
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- T. Kittelmann
- T. Klioutchnikova
- T. Kluge
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- T. Vu Anh
- T. W. Jones
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- T. Wengler
- T. Yamamura
- T. Yamanaka
- T. Yamazaki
- T. Z. Kowalski
- T. Zhao
- T. Ε½eniΕ‘
- Th. D. Papadopoulou
- U. Bitenc
- U. Blumenschein
- U. Bratzler
- U. De Sanctis
- U. Husemann
- U. K. Yang
- U. Klein
- U. Kruchonak
- U. Landgraf
- U. Mallik
- U. Parzefall
- U. SchΓ€fer
- U. Soldevila
- V. A. Bednyakov
- V. A. Gapienko
- V. A. Kantserov
- V. A. Kazanin
- V. A. Korotkov
- V. A. Kramarenko
- V. A. Mitsou
- V. A. Schegelsky
- V. Andrei
- V. B. Bobrovnikov
- V. B. Vinogradov
- V. Bansal
- V. Bartsch
- V. Boisvert
- V. Boldea
- V. Bortolotto
- V. BΓΌscher
- V. Canale
- V. Castillo Gimenez
- V. Cavasinni
- V. Chavda
- V. Chernyatin
- V. Cindro
- V. Consorti
- V. D. Peshekhonov
- V. Dao
- V. E. Ozcan
- V. F. Chepurnov
- V. Ferrara
- V. G. Bondarenko
- V. G. Zaets
- V. Gallo
- V. Garonne
- V. Giakoumopoulou
- V. Giangiobbe
- V. Gilewsky
- V. Grassi
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- V. I. Rud
- V. I. Vassilakopoulos
- V. Ippolito
- V. Izzo
- V. J. Guarino
- V. J. Martin
- V. Jain
- V. Juranek
- V. Kartvelishvili
- V. Kaushik
- V. Khovanskiy
- V. Kolesnikov
- V. Koreshev
- V. Kouskoura
- V. Kral
- V. Kukhtin
- V. Kus
- V. Lavorini
- V. Lendermann
- V. M. Kotov
- V. M. Romanov
- V. Malyshev
- V. Martinez Outschoorn
- V. Moeller
- V. N. Goryachev
- V. N. Gushchin
- V. Nguyen Thi Hong
- V. Nikolaenko
- V. O. Tikhomirov
- V. OβShea
- V. P. Lombardo
- V. P. Maleev
- V. Paolone
- V. Perez Reale
- V. Polychronakos
- V. Pozdnyakov
- V. R. Lacuesta
- V. Radescu
- V. Rojo
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- V. Scharf
- V. Simak
- V. Sipica
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- V. Sopko
- V. Tsiskaridze
- V. Tsulaia
- V. Tudorache
- V. V. Ammosov
- V. V. Kabachenko
- V. V. Kostyukhin
- V. V. Sulin
- V. V. Zmouchko
- V. Vacek
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- W. C. Wong
- W. Cleland
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- W. Davey
- W. Ehrenfeld
- W. F. Mader
- W. Fedorko
- W. Fernando
- W. G. Scott
- W. H. Bell
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- W. J. Dearnaley
- W. J. Mills
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- W. Ji
- W. K. Brooks
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- W. Mohr
- W. Park
- W. S. Lockman
- W. T. Meyer
- W. Taylor
- W. Trischuk
- W. Vandelli
- W. Verkerke
- W. Wagner
- W. Walkowiak
- W. Wiedenmann
- W. Willis
- X. Chen
- X. Espinal Curull
- X. Ju
- X. Lei
- X. Li
- X. Lou
- X. Portell Bueso
- X. Prudent
- X. Ruan
- X. S. Anduaga
- X. Sun
- X. Wu
- X. Zhang
- X. Zhuang
- Y. A. Kurochkin
- Y. A. Tikhonov
- Y. Arai
- Y. Azuma
- Y. B. Pan
- Y. Bai
- Y. Benhammou
- Y. Coadou
- Y. Davygora
- Y. Doi
- Y. F. Ryabov
- Y. Fang
- Y. Gusakov
- Y. Hasegawa
- Y. HernΓ‘ndez JimΓ©nez
- Y. Homma
- Y. Ikegami
- Y. Ilchenko
- Y. Jiang
- Y. Kataoka
- Y. Komori
- Y. Kulchitsky
- Y. Liu
- Y. Mahalalel
- Y. Makida
- Y. Ming
- Y. Munwes
- Y. Nagasaka
- Y. Nakahama
- Y. Ninomiya
- Y. Okumura
- Y. Oren
- Y. Pylypchenko
- Y. Rozen
- Y. S. Gao
- Y. Silver
- Y. Smirnov
- Y. Sugaya
- Y. Suzuki
- Y. Suzuki
- Y. Takahashi
- Y. Takubo
- Y. Tanaka
- Y. Tayalati
- Y. Unno
- Y. V. Grishkevich
- Y. Wu
- Y. Xie
- Y. Yamazaki
- Y. Yang
- Y. Yang
- Y. Yao
- Y. Yasu
- Y. Zhou
- Y. Zhu
- Y. Zolnierowski
- Yu. M. Sviridov
- Z. Czyczula
- Z. D. Greenwood
- Z. Dolezal
- Z. Drasal
- Z. Hajduk
- Z. Hubacek
- Z. Kohout
- Z. L. Ren
- Z. Liang
- Z. Marshall
- Z. Meng
- Z. Qian
- Z. Qin
- Z. Rurikova
- Z. V. Krumshteyn
- Z. van Kesteren
- Z. Weng
- Z. Yan
- Z. Yang
- Z. Zajacova
- Z. Zenonos
- Z. Zhan
- Z. Zhang
- Z. Zhao
- Z. Zinonos
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 06/03/2012
- Field of study
The uncertainty on the calorimeter energy response to jets of particles is
derived for the ATLAS experiment at the Large Hadron Collider (LHC). First, the
calorimeter response to single isolated charged hadrons is measured and
compared to the Monte Carlo simulation using proton-proton collisions at
centre-of-mass energies of sqrt(s) = 900 GeV and 7 TeV collected during 2009
and 2010. Then, using the decay of K_s and Lambda particles, the calorimeter
response to specific types of particles (positively and negatively charged
pions, protons, and anti-protons) is measured and compared to the Monte Carlo
predictions. Finally, the jet energy scale uncertainty is determined by
propagating the response uncertainty for single charged and neutral particles
to jets. The response uncertainty is 2-5% for central isolated hadrons and 1-3%
for the final calorimeter jet energy scale.Comment: 24 pages plus author list (36 pages total), 23 figures, 1 table,
submitted to European Physical Journal
A Chemical Screen Probing the Relationship between Mitochondrial Content and Cell Size
- Author
- AE Carpenter
- AM McGehee
- Anne E. Carpenter
- BK Wagner
- Bruce M. Spiegelman
- CA Virbasius
- David J. Logan
- DP Kelly
- E Nisoli
- F Li
- GE Truett
- GL Wright
- H Wu
- H Zong
- J Bain
- J Lin
- JM Huss
- Joseph Negri
- JW Posakony
- KL LaMarco
- KP Seiler
- M Kleiber
- M Wu
- MD Abramoff
- MJ Evans
- MW Karaman
- Nicola J. Tolliday
- P Echave
- P Puigserver
- SN Schreiber
- Thomas Hasaka
- Toshimori Kitami
- TR Jones
- Vamsi K. Mootha
- VK Mootha
- VK Mootha
- Yidong Bai
- Z Arany
- Z Wu
- Publication venue
- Public Library of Science
- Publication date
- 29/03/2012
- Field of study
The cellular content of mitochondria changes dynamically during development and in response to external stimuli, but the underlying mechanisms remain obscure. To systematically identify molecular probes and pathways that control mitochondrial abundance, we developed a high-throughput imaging assay that tracks both the per cell mitochondrial content and the cell size in confluent human umbilical vein endothelial cells. We screened 28,786 small molecules and observed that hundreds of small molecules are capable of increasing or decreasing the cellular content of mitochondria in a manner proportionate to cell size, revealing stereotyped control of these parameters. However, only a handful of compounds dissociate this relationship. We focus on one such compound, BRD6897, and demonstrate through secondary assays that it increases the cellular content of mitochondria as evidenced by fluorescence microscopy, mitochondrial protein content, and respiration, even after rigorous correction for cell size, cell volume, or total protein content. BRD6897 increases uncoupled respiration 1.6-fold in two different, non-dividing cell types. Based on electron microscopy, BRD6897 does not alter the percent of cytoplasmic area occupied by mitochondria, but instead, induces a striking increase in the electron density of existing mitochondria. The mechanism is independent of known transcriptional programs and is likely to be related to a blockade in the turnover of mitochondrial proteins. At present the molecular target of BRD6897 remains to be elucidated, but if identified, could reveal an important additional mechanism that governs mitochondrial biogenesis and turnover
Measurement of the production cross section for W-bosons in association with jets in pp collisions at s=7 TeV with the ATLAS detector
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- Publication venue
- Publication date
- 01/01/2011
- Field of study
This Letter reports on a first measurement of the inclusive W + jets cross section in proton-proton collisions at a centre-of-mass energy of 7 TeV at the LHC, with the ATLAS detector. Cross sections, in both the electron and muon decay modes of the W-boson, are presented as a function of jet multiplicity and of the transverse momentum of the leading and next-to-leading jets in the event. Measurements are also presented of the ratio of cross sections sigma (W + >= n)/sigma(W + >= n - 1) for inclusive jet multiplicities n = 1-4. The results, based on an integrated luminosity of 1.3 pb(-1), have been corrected for all known detector effects and are quoted in a limited and well-defined range of jet and lepton kinematics. The measured cross sections are compared to particle-level predictions based on perturbative QCD. Next-to-leading order calculations, studied here for n <= 2, are found in good agreement with the data. Leading-order multiparton event generators, normalized to the NNLO total cross section, describe the data well for all measured jet multiplicitie
Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector
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- Yurkewicz A
- Zaets VG
- Zaidan R
- Zaitsev AM
- Zajacova Z
- Zalite YK
- Zanello L
- Zarzhitsky P
- Zaytsev A
- Zdrazil M
- Zeitnitz C
- Zeller M
- Zema PF
- Zemla A
- Zendler C
- Zenin AV
- Zenin O
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- Zenonos Z
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- Zerwas D
- Zhan Z
- Zhang D
- Zhang H
- Zhang J
- Zhang X
- Zhang Z
- Zhao L
- Zhao T
- Zhao Z
- Zhemchugov A
- Zheng S
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zieminska D
- Zilka B
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zolnierowski Y
- Zsenei A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 31/12/2010
- Field of study
The inclusive and dijet production cross-sections have been measured for jets
containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass
energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The
measurements use data corresponding to an integrated luminosity of 34 pb^-1.
The b-jets are identified using either a lifetime-based method, where secondary
decay vertices of b-hadrons in jets are reconstructed using information from
the tracking detectors, or a muon-based method where the presence of a muon is
used to identify semileptonic decays of b-hadrons inside jets. The inclusive
b-jet cross-section is measured as a function of transverse momentum in the
range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet
cross-section is measured as a function of the dijet invariant mass in the
range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets
and the angular variable chi in two dijet mass regions. The results are
compared with next-to-leading-order QCD predictions. Good agreement is observed
between the measured cross-sections and the predictions obtained using POWHEG +
Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet
cross-section. However, it does not reproduce the measured inclusive
cross-section well, particularly for central b-jets with large transverse
momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final
version published in European Physical Journal
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogana T
- Akesson TPA
- Akimoto G
- Akimov AV
- Akiyama A
- Aktas A
- Alam MA
- Alam MS
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alviggi MG
- Amako K
- Amaral P
- Amelung C
- Ammosov VV
- Amorim A
- Amoros G
- Amram N
- Anastopoulos C
- Ancu LS
- Andari N
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- Anh TV
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- Antonaki A
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- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2013
- Field of study
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of βs = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pTβ₯20 GeV and pseudorapidities {pipe}Ξ·{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}Ξ·{pipe}<0. 8) for jets with 60β€pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2β€{pipe}Ξ·{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. Β© 2013 CERN for the benefit of the ATLAS collaboration
Reference Intervals in Healthy Adult Ugandan Blood Donors and Their Impact on Conducting International Vaccine Trials
- Author
- A Kratz
- A Tsegaye
- AG Shaper
- Benson Ouma
- BJ Bain
- CJ Badenhorst
- D Menard
- D Menard
- Denis Kyabaggu
- E Saathoff
- ES Lugada
- Fred Wabwire-Mangen
- GC Ezeilo
- GC Ezeilo
- GC Ezeilo
- Hannah Kibuuka
- HR Black
- Joseph Wandege
- Leigh Anne Eller
- MA Eller
- Mark S. de Souza
- Merlin L. Robb
- Michael A. Eller
- Michael Goodyear
- Nelson L. Michael
- Peter Kataaha
- R Diagnostics
- Richard Tumusiime
- Ronald Sanya
- SB Tugume
- W Pilis
- Warren B. Sateren
- Publication venue
- Public Library of Science
- Publication date
- 11/12/2008
- Field of study
BACKGROUND: Clinical trials are increasingly being conducted internationally. In order to ensure enrollment of healthy participants and proper safety evaluation of vaccine candidates, established reference intervals for clinical tests are required in the target population. METHODOLOGY/PRINCIPAL FINDINGS: We report a reference range study conducted in Ugandan adult blood bank donors establishing reference intervals for hematology and clinical chemistry parameters. Several differences were observed when compared to previously established values from the United States, most notably in neutrophils and eosinophils. CONCLUSIONS/SIGNIFICANCE: In a recently conducted vaccine trial in Uganda, 31 percent (n = 69) of volunteers screened (n = 223) were excluded due to hematologic abnormalities. If local reference ranges had been employed, 83% of those screened out due to these abnormalities could have been included in the study, drastically reducing workload and cost associated with the screening process. In addition, toxicity tables used in vaccine and drug trial safety evaluations may need adjustment as some clinical reference ranges determined in this study overlap with grade 1 and grade 2 adverse events
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