17 research outputs found
Experimental investigation on the impact of coal fines generation and migration on coal permeability
Measurements of the coal fines production and the impact of these fines on the permeability of two coals from the Bowen Basin, Australia, were performed at different flow conditions (single-phase water or gas, two-phase water and gas) and pressure conditions. The fines collected from each coal samples ranged in size from 1 mu m to 14 mu m. For both coal samples, during the first 50 h, the permeability decreases from 0.005 mD and 0.048 mD by 60.9% and 85%, respectively, followed by gradual decline with fluctuations. By the end of water injection, the permeability drops by 88% and 89%, respectively. This phenomenon is attributed to the counteraction between formation damage (cleats plugging and coal fines settlement) and breakthrough of coal fines from the samples (widened cleats). It was found that coal fines volumetric production is proportional to the third power of flow velocity once the flow paths for coal fines are established. The critical flow velocities of coal fines production for both samples were also obtained. For hydrophobic coal, water-drive-gas two-phase flow introduces abrupt permeability loss due to coal fines generation and migration. Furthermore, pauses (well shut-in) in the experiments cause slight permeability drops. A comparison between the two samples indicates that narrower and less connected cleating system results in more frequent coal fines generation and migration, resulting in significant permeability fluctuations with general decreasing trend. Tortuosity of the cleats can enhance the deterioration in permeability by coal fines behaviours. This study delivers fundamental understandings of coal fines generation and migration during the CSG production process, and useful guidelines are suggested to be implemented in the field to minimize production loss induced by coal fines behaviours
Experimental study on permeability evolution of slender coal pillar of entry driven along goaf
Under the condition of roadway driving along goaf, slender coal pillar is affected by multiple mining-induced disturbances, and the permeability of coal and rock mass affected by mining will change due to the development and compaction of mining fractures and primary fractures. Determining the evolution of slender coal pillar permeability at different mining stages is the theoretical basis for the prevention and control of gas water disasters in adjacent goaf at the same layer. Taking the mining with slender coal gate pillar of the Carboniferous extra thick coal seam in Datong Mining Area as the engineering background, the distribution characteristics of the stress field for the slender coal gate pillar of the coal seam in different mining stages are comprehensively determined by the methods of geostress testing and numerical simulation, which provides a basis for the determination of the stress path for experimental research. The DJG - Ⅱ triaxial loading coal rock seepage testing equipment was used to conduct experimental research on the evolution of coal pillar permeability in different mining stages. The research results are as follows: The quantitative influence relationship between permeability and stress of slender coal gate pillar in different mining stages is established. The overall performance is that the permeability decreases with the increase of axial stress, and the permeability increases with the decrease of axial pressure in unloading stage; It reveals the evolution of stress strain permeability of the coal pillar in different mining stages. When loading and unloading in the first and second stages, the deformation of coal sample is still in the elastic deformation stage, and the change amplitude and rate of permeability are relatively gentle. In the third mining-impacted stage, the irreversible plastic failure of the specimen made the permeability increase sharply, and the rate of increase was also significantly greater than the first two mining stages. The permeability of slender coal pillar increased by 324.389 times compared with the initial permeability. In this stage, the slender coal pillar was damaged and lost its gas water barrier performance. It was clear that the 6 m small coal pillar was not damaged in the first two mining stages of the super thick coal seam gob side entry project. The research results can provide reference or theoretical support for the study of permeability evolution characteristics of slender coal pillar in different mining stages, and the prevention and control of gas water disasters in adjacent goaf under the condition of gob side entry mining in hard roof extra thick coal seams
Characterization of coal fines generation: a micro-scale investigation
Coal fines are commonly generated as by-product during coalbed methane production mainly due to the interaction of coal with inseam water flow. A portion of the created coal fines may settle and plug the coal cleats and hydraulic fractures due to the gravity and coal pore size constraint. This could result in the reduction of coal permeability and blockage of coalbed methane wells or gas drainage boreholes. Despite the increasing awareness of the importance of understanding coal fines, limited research has been carried out on the characterization of coal fines creation. This study aimed to numerically characterize the generation process of coal fines in micro-scale coal cleats. The Scanning Electron Microscopy (SEM) images for a coal sample from Bulli Seam of the Sydney Basin in Australia were obtained and analysed to determine the actual cleat geometries and the characteristics of coal fines distribution. Then a fully coupled fluid-structure numerical model was developed to identify the creation process of coal fines at micro-scale. The impact of pertinent production conditions on coal fines generation was studied, including production pressure drawdown, temperature, coal fines Young's modulus and strength. The SEM images revealed that the particle size distributions of the coal fines in the examined cleats were in the order of hundreds of nanometres to several microns. The results of the numerical studies showed the coal fines production increased with pressure build-up, and decreased with increasing coal fines strength with more sensitivity compared with pressure. Critical values for production pressure drawdown were obtained, above which failure area began to expand; threshold values were also determined, below which remarkable reduction of coal fines production was achieved. Coal cleat geometry plays an important role in determining coal fines production. It was noted that exposed microstructures, cleat elbow regions and micro-fracture tips are more likely to generate coal fines. Based on these findings, guidance can be provided on the control of production conditions to mitigate coal fines issue, and new insight into where and how coal fines are created by inseam water flow can be achieved. (C) 2015 Elsevier B.V. All rights reserved
CCN1, a Pro-Inflammatory Factor, Aggravates Psoriasis Skin Lesions by Promoting Keratinocyte Activation
Psoriasis is a common chronic skin disease characterized by epidermal hyperplasia and inflammation. The pathogenesis of psoriasis is multifactorial and is not fully understood. Here we demonstrate that CCN1 (also called Cyr61, which is short for cysteine-rich 61), an extracellular matrix protein that is also considered a pro-inflammatory factor, is highly expressed in the lesional skin of psoriasis patients, as well as in that of imiquimod (IMQ)- and IL-23-treated psoriasis-like mice. Then we show that blocking CCN1 function in vivo attenuates epidermal hyperplasia and inflammation in psoriasis-like mice. Further, in primary cultured normal human keratinocytes and HaCaT (human keratinocyte cell line) cells, CCN1 promotes keratinocyte activation, including the proliferation and expression of immune-related molecules. Finally, we observe that integrin α6β1 is the receptor of CCN1 in keratinocytes, and CCN1 stimulation activates the downstream phosphoinositide-3 kinase/Akt/NF-κB signaling pathway. Taken together, our findings reveal that CCN1 has a critical role in psoriasis pathogenesis. Moreover, as CCN1 is a secreted extracellular matrix (ECM) protein, our study also provides evidence that ECM, which is involved in psoriatic pathogenesis, could be a potent target for psoriasis treatment
Qwen Technical Report
Large language models (LLMs) have revolutionized the field of artificial
intelligence, enabling natural language processing tasks that were previously
thought to be exclusive to humans. In this work, we introduce Qwen, the first
installment of our large language model series. Qwen is a comprehensive
language model series that encompasses distinct models with varying parameter
counts. It includes Qwen, the base pretrained language models, and Qwen-Chat,
the chat models finetuned with human alignment techniques. The base language
models consistently demonstrate superior performance across a multitude of
downstream tasks, and the chat models, particularly those trained using
Reinforcement Learning from Human Feedback (RLHF), are highly competitive. The
chat models possess advanced tool-use and planning capabilities for creating
agent applications, showcasing impressive performance even when compared to
bigger models on complex tasks like utilizing a code interpreter. Furthermore,
we have developed coding-specialized models, Code-Qwen and Code-Qwen-Chat, as
well as mathematics-focused models, Math-Qwen-Chat, which are built upon base
language models. These models demonstrate significantly improved performance in
comparison with open-source models, and slightly fall behind the proprietary
models.Comment: 59 pages, 5 figure
Coal reservoir characterization
Characterizing coal reservoir is a critical part of gaining reservoir information for the development of a reservoir model. This chapter comprehensively reviews the techniques and/or methods used to characterize a coal reservoir with respect to the following three key parameters: coal porosity, coal permeability, and coalbed gas in place. The principle for each technique is explained with some specific examples; the strengths and limitations of each method are also provided in the context. It is expected that this chapter provides a useful introduction to coal reservoir characterization for all professionals working on this field, particularly the people in the industry
Predicting erosion-induced water inrush of karst collapse pillars using inverse velocity theory
Although the impact of Karst Collapse Pillars (KCPs) on water inrush has been widely recognized and studied, few have investigated the fluid-solid interaction, the particles migration inside KCPs, and the evolution feature of water inrush channels. Moreover, an effective approach to reliably predict the water inrush time has yet to be developed. In this work, a suite of fully coupled governing equations considering the processes of water flow, fracture erosion, and the change of rock permeability due to erosion were presented. The inverse velocity theory was then introduced to predict the water inrush time under different geological and flow conditions. The impact of four different controlling factors on the fracture geometry change, water flow, and inrush time was discussed in detail. The results showed that the inverse velocity theory was capable of predicting the occurrences of water inrush under different conditions, and the time of water inrush had a power relationship with the rock heterogeneity, water pressure, and initial particle concentration and an exponential relationship with the initial fracture apertures. The general approach developed in this work can be extended to other engineering applications such as the tunneling and tailing dam erosion
Impact of flow regimes on coal fines generation during coal seam gas production process
This study presents the development and application of a fully coupled numerical model that integrates different flow regimes and the generation of coal fines. The Scanning Electron Microscopy (SEM) was employed to obtain coal cleat geometry at the micro-scale. Based on the real cleat geometry, the Phase Field Method (PFM) was used to simulate the two-phase flow and the combination of shear and tensile failure criteria was selected to evaluate the generation of coal fines. The results reveal that more coal fines are generated in two-phase flow than single-phase flow. For the two-phase flow conditions, residual displaced phase is observed inside the micro-roughness of coal cleat. Majority of coal fines are generated in these regions due to the substantial pressure force induced by significant pressure difference between the trapped phase and the invading phase. Coal wettability plays an important role in coal fines generation. Using the wetting phase as the injection phase will produce one order of magnitude more coal fines than that from the other way. Moreover, the change of fluid phase inside the cleat can create considerable pressure fluctuations up to several kPa, which is not favorable in managing the production of coal fines