1,281 research outputs found
Measuring galaxy [OII] emission line doublet with future ground-based wide-field spectroscopic surveys
The next generation of wide-field spectroscopic redshift surveys will map the
large-scale galaxy distribution in the redshift range 0.7< z<2 to measure
baryonic acoustic oscillations (BAO). The primary optical signature used in
this redshift range comes from the [OII] emission line doublet, which provides
a unique redshift identification that can minimize confusion with other single
emission lines. To derive the required spectrograph resolution for these
redshift surveys, we simulate observations of the [OII] (3727,3729) doublet for
various instrument resolutions, and line velocities. We foresee two strategies
about the choice of the resolution for future spectrographs for BAO surveys.
For bright [OII] emitter surveys ([OII] flux ~30.10^{-17} erg /cm2/s like
SDSS-IV/eBOSS), a resolution of R~3300 allows the separation of 90 percent of
the doublets. The impact of the sky lines on the completeness in redshift is
less than 6 percent. For faint [OII] emitter surveys ([OII] flux ~10.10^{-17}
erg /cm2/s like DESi), the detection improves continuously with resolution, so
we recommend the highest possible resolution, the limit being given by the
number of pixels (4k by 4k) on the detector and the number of spectroscopic
channels (2 or 3).Comment: 5 pages, 1 figur
Energy dependence of {\rm K} and hyperon production at CERN SPS
Recent results on K and hyperon production in Pb-Pb collisions at
40 and 158 GeV/ beam momentum from the NA57 experiment at CERN SPS are
presented. Yields and ratios are compared with those measured by the NA49
experiment, where available. The centrality dependence of the yields and a
comparison with the higher collision energy data from RHIC are discussed.Comment: 4 pages, 3 figures, proceedings of QM2004 conferenc
The Impact of Business Ownership Change on Employee Relations: Buy-outs in the UK and the Netherlands
A buy-out is a fundamental change in the structure of ownership that may affect the way employee relations develop within an organisation. Little is known about the impact of buyouts upon employee relations. This paper aims to address this gap. We focus on two main questions. First, what are the effects of a buy-out on employee relations in an organisation? Second, does the national institutional context affect the impact of buy-outs on employee relations? The paper reports changes to employee relations in buy-outs in the contrasting institutional environments of the UK and the Netherlands. Overall, we find that buy-outs positively affect HR practices with increases in training, employee involvement, the number of employees and pay levels. The positive effects appear to be significantly stronger in a less institutionalised environment like the UK than the more institutionalised environment of the Netherlands. Buy-outs raised HRM practices in the UK to a level closer although still below that of Dutch buy-outs
An Upper Palaeolithic Proto-writing System and Phenological Calendar
In at least 400 European caves such as Lascaux, Chauvet and Altamira, Upper Palaeolithic Homo sapiens groups drew, painted and engraved non-figurative signs from at least ~42,000 BP and figurative images (notably animals) from at least 37,000 BP. Since their discovery ~150 years ago, the purpose or meaning of European Upper Palaeolithic non-figurative signs has eluded researchers. Despite this, specialists assume that they were notational in some way. Using a database of images spanning the European Upper Palaeolithic, we suggest how three of the most frequently occurring signs—the line , the dot , and the —functioned as units of communication. We demonstrate that when found in close association with images of animals the line and dot constitute numbers denoting months, and form constituent parts of a local phenological/meteorological calendar beginning in spring and recording time from this point in lunar months. We also demonstrate that the sign, one of the most frequently occurring signs in Palaeolithic non-figurative art, has the meaning . The position of the within a sequence of marks denotes month of parturition, an ordinal representation of number in contrast to the cardinal representation used in tallies. Our data indicate that the purpose of this system of associating animals with calendar information was to record and convey seasonal behavioural information about specific prey taxa in the geographical regions of concern. We suggest a specific way in which the pairing of numbers with animal subjects constituted a complete unit of meaning—a notational system combined with its subject—that provides us with a specific insight into what one set of notational marks means. It gives us our first specific reading of European Upper Palaeolithic communication, the first known writing in the history of Homo sapiens
Anti-JNK2 peptide–siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice
M32+/-1
WFPC-2 images are used to study the central structure of M31, M32, and M33.
The dimmer peak, P2, of the M31 double nucleus is centered on the bulge to
0.1", implying that it is the dynamical center of M31. P2 contains a compact
source discovered by King et al. (1995) at 1700 A. This source is resolved,
with r_{1/2} approx0.2 pc. It dominates the nucleus at 3000 A, and is
consistent with late B-early A stars. This probable cluster may consist of
young stars and be an older version of the cluster of hot stars at the center
of the Milky Way, or it may consist of heavier stars built up from collisions
in a possible cold disk of stars orbiting P2. In M32, the central cusp rises
into the HST limit with gamma approx0.5, and the central density
rho_0>10^7M_sol pc^-3. The V-I and U-V color profiles are flat, and there is no
sign of an inner disk, dust, or any other structure. This total lack of
features seems at variance with a nominal stellar collision time of 2 X 10^10
yr, which implies that a significant fraction of the light in the central pixel
should come from blue stragglers. InM33, the nucleus has an extremely steep
gamma=1.49 power-law profile for 0.05"<r<0.2" that becomes shallower as the HST
resolution limit is approached. The profile for r<0.04" has either a gamma
approx 0.8 cusp or a small core with r_c ~<0.13 pc. The central density is
rho_0 > 2 10^6M_sol pc^-3, and the implied relaxation time is only ~3 X 10^6
yr, indicating that the nucleus is highly relaxed. The accompanying short
collision time of 7 X 10^9 yr predicts a central blue straggler component
quantitatively consistent with the strong V-I and B-R color gradients seen with
HST and from the ground.Comment: 44 pages, 22 figures (7 as separate JPEG images), submitted to The
Astronomical Journal. Full postscript image available at
http://www.noao.edu/noao/staff/lauer/lauer_paper
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A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis.
Primary biliary cholangitis (PBC) is typically associated with elevated serum bile acid levels and pruritus, but pruritus is often refractory to treatment with existing therapies. This phase 2 study assessed the efficacy and safety of maralixibat, a selective, ileal, apical, sodium-dependent, bile acid transporter inhibitor, in adults with PBC and pruritus. Adults with PBC and pruritus who had received ursodeoxycholic acid (UDCA) for ≥6 months or were intolerant to UDCA were randomized 2:1 to maralixibat (10 or 20 mg/day) or placebo for 13 weeks in combination with UDCA (when tolerated). The primary outcome was change in Adult Itch Reported Outcome (ItchRO™) average weekly sum score (0, no itching; 70, maximum itching) from baseline to week 13/early termination (ET). The study enrolled 66 patients (maralixibat [both doses combined], n = 42; placebo, n = 24). Mean ItchRO™ weekly sum scores decreased from baseline to week 13/ET with maralixibat (-26.5; 95% confidence interval [CI], -31.8, -21.2) and placebo (-23.4; 95% CI, -30.3, -16.4). The difference between groups was not significant (P = 0.48). In the maralixibat and placebo groups, adverse events (AEs) were reported in 97.6% and 70.8% of patients, respectively. Gastrointestinal disorders were the most frequently reported AEs (maralixibat, 78.6%; placebo, 50.0%). Conclusion: Reductions in pruritus did not differ significantly between maralixibat and placebo. However, a large placebo effect may have confounded assessment of pruritus. Lessons learned from this rigorously designed and executed trial are indispensable for understanding how to approach trials assessing pruritus as the primary endpoint and the therapeutic window of bile acid uptake inhibition as a therapeutic strategy in PBC
The thermodynamic balance of the Weddell Gyre
The thermodynamic balance of the Weddell Gyre is assessed from an inverse estimate of the circulation across the gyre's rim. The gyre experiences a weak net buoyancy gain that arises from a leading-order cancellation between two opposing contributions, linked to two cells of water mass transformation and diapycnal overturning. The lower cell involves a cooling-driven densification of 8.4 ± 2.0 Sv of Circumpolar Deep Water and Antarctic Bottom Water near the gyre's southern and western margins. The upper cell entails a freshening-driven conversion of 4.9 ± 2.0 Sv of Circumpolar Deep Water into lighter upper-ocean waters within the gyre interior. The distinct role of salinity between the two cells stems from opposing salinity changes induced by sea ice production, meteoric sources and admixture of fresh upper-ocean waters in the lower cell, which contrasts with coherent reductions in salinity associated with sea ice melting and meteoric sources in the upper cell
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