Die antwoord van die Calvinistiese filosofie en praktyk van die opvoeding op die wysgerigreligieuse eise van die moderne tyd

Ons lewe in woelige, wonderlike tye. Beskrywing hiervan is aan die orde van die dag, elkeen met ander klem en treffende byvoeglike naamwoorde. Dit het mode geword om ons probleme en sogenaamde krisisse terug te voer tot die besondersheid van ons moderne eeu. Die opvoedkundige terrein is hiervan ook ’n getroue verteenwoordiger. Nuwe en besonderse tye verg nuwe en besonderse opvoedkundige benadering. Ons huise lyk en is anders, ons ouers eis en gee anders, ons gemeenskap tree anders op en is baie meer gekompliseerd, ons kinders mag psigies nog na die van ons voorgeslagte lyk en aard, maar tog is die verhoudings so totaal verskillend dat hulle maklik soos vreemde wesens vergelyk

Opvoedkunde aan die P.U. vir C.H.O. – ‘n Toekomsblik

Die Potchefstroomse Universiteit het eers sedert 1925 ’n leerstoel in die Opvoedkunde maar beoefen al die opleiding en wetenskaplike toerusting van onderwysers sedert sy stigting in 1869

H.J.J. Bingle en die stryd om Christelike opvoeding en onderwys

Dis vir my nie maklik om oor prof. dr. H.J.J. Bingle te skrywe nie omdat dit so moeilik gaan om afstand te verkry: ons was lewenslank te na aan mekaar. Hierdie verband strek van ons kinderdae af, daar in 1921 se koers, in die legendariese Karoodorpie, Venterstad. Toe ons paaie teen die einde van 1923 uiteengegaan het met die vaderlose gesin se vertrek na Steynsburg, was daar die hereniging in 1928 toe ons albei studente aan die PUK was, hy in die geesteswetenskappe en ek in die natuurwetenskappe. In 1931 het ons toe weer saam aan die voete van ons leermeester, J. Chris Coetzee, gesit. Daar het ons opvoedkundige vorming gestalte begin aanneem en dit het tot by sy aftrede in 1977 geduur en is sekerlik nooit afgesluit nie

Prognostic biomarker soluble ST2 exhibits diurnal variation in chronic heart failure patients

Aim: Soluble suppression of tumorigenicity-2 (sST2) is a strong prognostic biomarker in heart failure. The emerging understanding of circadian biology in cardiovascular disease may lead to novel applications in prognosis and diagnosis and may provide insight into mechanistic aspects of the disease–biomarker interaction. So far, it is unknown whether sST2 exhibits a diurnal rhythm. Repeated measurements of sST2 may aid in clinical decision making. The goal of this study was to investigate whether sST2 exhibits diurnal variation in patients with heart failure with reduced ejection fraction (HFrEF) and in control subjects, thereby enhancing its diagnostic and prognostic values. Methods and results: The study comprised 32 subjects: 16 HFrEF patients and 16 controls. Blood was collected at seven subsequent time points during a 24 h time period. sST2, N-terminal pro-B-type natriuretic peptide (NT-proBNP), melatonin, and cortisol were measured from serum. Peak values of sST2 clustered at daytime (modal value: 5 p.m.) in 87.6% of all subjects (81.3% of patients, P = 0.021; 93.8% of controls, P = 0.001), and minimum concentrations at night-time (modal value: 5 a.m.) in 84.4% (87.5% of patients, P = 0.004 81.3% of controls, P = 0.021). A cosinor analysis of mean normalized sST2 values revealed significant cosine shaped 24 h oscillations of patients (P = 0.026) and controls (P = 0.037). NT-proBNP in contrast did not show a diurnal rhythm, while melatonin and cortisol patterns were intact in all subjects. Conclusions: sST2 exhibits a diurnal rhythm with lower values in the morning than in the late afternoon. This new insight could lead to refinement of its diagnostic and prognostic values through specified and consistent sampling times with repeated measurements. For example, by measuring sST2 during the afternoon, when levels are at their highest, false negatives on prognosis prediction could be avoided

External validation of computed tomography decision rules for minor head injury: Prospective, multicentre cohort study in the Netherlands

Objective To externally validate four commonly used rules in computed tomography (CT) for minor head injury. Design Prospective, multicentre cohort study. Setting Three university and six non-university hospitals in the Netherlands. Participants Consecutive adult patients aged 16 years and over who presented with minor head injury at the emergency department with a Glasgow coma scale score of 13-15 between March 2015 and December 2016. Main outcome measures The primary outcome was any intracrania

Scholarly publishing depends on peer reviewers

The peer-review crisis is posing a risk to the scholarly peer-reviewed journal system. Journals have to ask many potential peer reviewers to obtain a minimum acceptable number of peers accepting reviewing a manuscript. Several solutions have been suggested to overcome this shortage. From reimbursing for the job, to eliminating pre-publication reviews, one cannot predict which is more dangerous for the future of scholarly publishing. And, why not acknowledging their contribution to the final version of the article published? PubMed created two categories of contributors: authors [AU] and collaborators [IR]. Why not a third category for the peer-reviewer?Scopu