Characterisation of the Etching Quality in Micro-Electro-Mechanical Systems by Thermal Transient Methodology

Our paper presents a non-destructive thermal transient measurement method that is able to reveal differences even in the micron size range of MEMS structures. Devices of the same design can have differences in their sacrificial layers as consequence of the differences in their manufacturing processes e.g. different etching times. We have made simulations examining how the etching quality reflects in the thermal behaviour of devices. These simulations predicted change in the thermal behaviour of MEMS structures having differences in their sacrificial layers. The theory was tested with measurements of similar MEMS devices prepared with different etching times. In the measurements we used the T3Ster thermal transient tester equipment. The results show that deviations in the devices, as consequence of the different etching times, result in different temperature elevations and manifest also as shift in time in the relevant temperature transient curves.Comment: Submitted on behalf of TIMA Editions (http://irevues.inist.fr/tima-editions

Theoretical aspects of the study of top quark properties

We review some recent theoretical progresses towards the determination of the top-quark couplings beyond the standard model. We briefly introduce the global effective field theory approach to the top-quark production and decay processes, and discuss the most useful observables to constrain the deviations. Recent improvements with a focus on QCD corrections and corresponding tools are also discussed.Comment: 8 pages, 6 figures. Based on plenary talk given at LHCP2017, Shanghai, 15-20 May 201

Picoliter-volume inkjet printing into planar microdevice reservoirs for low-waste, high-capacity drug loading.

Oral delivery of therapeutics is the preferred route for systemic drug administration due to ease of access and improved patient compliance. However, many therapeutics suffer from low oral bioavailability due to low pH and enzymatic conditions, poor cellular permeability, and low residence time. Microfabrication techniques have been used to create planar, asymmetric microdevices for oral drug delivery to address these limitations. The geometry of these microdevices facilitates prolonged drug exposure with unidirectional release of drug toward gastrointestinal epithelium. While these devices have significantly enhanced drug permeability in vitro and in vivo, loading drug into the micron-scale reservoirs of the devices in a low-waste, high-capacity manner remains challenging. Here, we use picoliter-volume inkjet printing to load topotecan and insulin into planar microdevices efficiently. Following a simple surface functionalization step, drug solution can be spotted into the microdevice reservoir. We show that relatively high capacities of both topotecan and insulin can be loaded into microdevices in a rapid, automated process with little to no drug waste

Control variates for stochastic gradient MCMC

It is well known that Markov chain Monte Carlo (MCMC) methods scale poorly with dataset size. A popular class of methods for solving this issue is stochastic gradient MCMC (SGMCMC). These methods use a noisy estimate of the gradient of the log-posterior, which reduces the per iteration computational cost of the algorithm. Despite this, there are a number of results suggesting that stochastic gradient Langevin dynamics (SGLD), probably the most popular of these methods, still has computational cost proportional to the dataset size. We suggest an alternative log-posterior gradient estimate for stochastic gradient MCMC which uses control variates to reduce the variance. We analyse SGLD using this gradient estimate, and show that, under log-concavity assumptions on the target distribution, the computational cost required for a given level of accuracy is independent of the dataset size. Next we show that a different control variate technique, known as zero variance control variates, can be applied to SGMCMC algorithms for free. This post-processing step improves the inference of the algorithm by reducing the variance of the MCMC output. Zero variance control variates rely on the gradient of the log-posterior; we explore how the variance reduction is affected by replacing this with the noisy gradient estimate calculated by SGMCMC

The population of hot subdwarf stars studied with Gaia I. The catalogue of known hot subdwarf stars

In preparation for the upcoming all-sky data releases of the Gaia mission we compiled a catalogue of known hot subdwarf stars and candidates drawn from the literature and yet unpublished databases. The catalogue contains 5613 unique sources and provides multi-band photometry from the ultraviolet to the far infrared, ground based proper motions, classifications based on spectroscopy and colours, published atmospheric parameters, radial velocities and light curve variability information. Using several different techniques we removed outliers and misclassified objects. By matching this catalogue with astrometric and photometric data from the Gaia mission, we will develop selection criteria to construct a homogeneous, magnitude-limited all-sky catalogue of hot subdwarf stars based on Gaia data.Comment: 11 pages, A&A accepte

NFV service dynamicity with a DevOps approach : demonstrating zero-touch deployment & operations

Next generation network services will be realized by NFV-based microservices to enable greater dynamics in deployment and operations. Here, we present a demonstrator that realizes this concept using the NFV platform built in the EU FP7 project UNIFY. Using the example of an Elastic Router service, we show automated deployment and configuration of service components as well as corresponding monitoring components facilitating automated scaling of the entire service. We also demonstrate automatic execution of troubleshooting and debugging actions. Operations of the service are inspired by DevOps principles, enabling quick detection of operational conditions and fast corrective actions. This demo conveys essential insights on how the life-cycle of an NFV-based network service may be realized in future NFV platforms

A large-scale, near-sea level, silicic caldera-forming eruption in Efate? An alternative model for the 1 Ma Efate Pumice Formation, Vanuatu, SW-Pacific

No abstract availabl

Notes

Notes by Charles M. Urruela, Norman B. Thirion, R. F. Swisher, Peter Francis Nemeth, Walter C. Ivansevic, Charles M. Boynton, Theodore P. Frericks, Hal Hunter, and J. D. Kelly