24,122 research outputs found
Pressure-control purge panel for automatic butt welding
Modification of a purge panel for use in an automatic butt weld reduces the drop in pressure between the regulators and the weld head and tube purge fitting. The invention affects air regulators for plants, regulating circuits for pneumatic valves, and automatic welding machines
FormCalc 8: Better Algebra and Vectorization
We present Version 8 of the Feynman-diagram calculator FormCalc. New features
include in particular significantly improved algebraic simplification as well
as vectorization of the generated code. The Cuba Library, used in FormCalc,
features checkpointing to disk for all integration algorithms.Comment: 7 pages, LaTeX, proceedings contribution to ACAT 2013, Beijing,
China, 16-21 May 201
Measurements in the Turbulent Boundary Layer at Constant Pressure in Subsonic and Supersonic Flow. Part 2: Laser-Doppler Velocity Measurements
A description of both the mean and the fluctuating components of the flow, and of the Reynolds stress as observed using a dual forward scattering laser-Doppler velocimeter is presented. A detailed description of the instrument and of the data analysis techniques were included in order to fully document the data. A detailed comparison was made between the laser-Doppler results and those presented in Part 1, and an assessment was made of the ability of the laser-Doppler velocimeter to measure the details of the flows involved
Imaging through turbulence with a quadrature-phase optical interferometer
We present an improved technique for imaging through turbulence at visible wavelengths using a rotation shearing pupil-plane interferometer, intended for astronomical and terrestrial imaging applications. While previous astronomical rotation shearing interferometers have made only visibility modulus measurements, this interferometer makes four simultaneous measurements on each interferometric baseline, with phase differences of π/2 between each measurement, allowing complex visibility measurements (modulus and phase) across the entire input pupil in a single exposure. This technique offers excellent wavefront resolution, allowing operation at visible wavelengths on large apertures, is potentially immune to amplitude fluctuations (scintillation), and may offer superior calibration capabilities to other imaging techniques. The interferometer has been tested in the laboratory under weakly aberrating conditions and at Palomar Observatory under ordinary astronomical observing conditions. This research is based partly on observations obtained at the Hale Telescope
Comparison of TCGA and GENIE genomic datasets for the detection of clinically actionable alterations in breast cancer.
Whole exome sequencing (WES), targeted gene panel sequencing and single nucleotide polymorphism (SNP) arrays are increasingly used for the identification of actionable alterations that are critical to cancer care. Here, we compared The Cancer Genome Atlas (TCGA) and the Genomics Evidence Neoplasia Information Exchange (GENIE) breast cancer genomic datasets (array and next generation sequencing (NGS) data) in detecting genomic alterations in clinically relevant genes. We performed an in silico analysis to determine the concordance in the frequencies of actionable mutations and copy number alterations/aberrations (CNAs) in the two most common breast cancer histologies, invasive lobular and invasive ductal carcinoma. We found that targeted sequencing identified a larger number of mutational hotspots and clinically significant amplifications that would have been missed by WES and SNP arrays in many actionable genes such as PIK3CA, EGFR, AKT3, FGFR1, ERBB2, ERBB3 and ESR1. The striking differences between the number of mutational hotspots and CNAs generated from these platforms highlight a number of factors that should be considered in the interpretation of array and NGS-based genomic data for precision medicine. Targeted panel sequencing was preferable to WES to define the full spectrum of somatic mutations present in a tumor
Randomisation of Pulse Phases for Unambiguous and Robust Quantum Sensing
We develop theoretically and demonstrate experimentally a universal dynamical
decoupling method for robust quantum sensing with unambiguous signal
identification. Our method uses randomisation of control pulses to suppress
simultaneously two types of errors in the measured spectra that would otherwise
lead to false signal identification. These are spurious responses due to
finite-width pulses, as well as signal distortion caused by pulse
imperfections. For the cases of nanoscale nuclear spin sensing and AC
magnetometry, we benchmark the performance of the protocol with a single
nitrogen vacancy centre in diamond against widely used non-randomised pulse
sequences. Our method is general and can be combined with existing multipulse
quantum sensing sequences to enhance their performance
Effective chiral restoration in the rho'-meson in lattice QCD
In simulations with dynamical quarks it has been established that the ground
state rho in the infrared is a strong mixture of the two chiral representations
(0,1)+(1,0) and (1/2,1/2)_b. Its angular momentum content is approximately the
3S1 partial wave which is consistent with the quark model. Effective chiral
restoration in an excited rho-meson would require that in the infrared this
meson couples predominantly to one of the two representations. The variational
method allows one to study the mixing of interpolators with different chiral
transformation properties in the non-perturbatively determined excited state at
different resolution scales. We present results for the first excited state of
the rho-meson using simulations with n_f=2 dynamical quarks. We point out, that
in the infrared a leading contribution to rho'= rho(1450) comes from
(1/2,1/2)_b, in contrast to the rho. Its approximate chiral partner would be a
h_1(1380) state. The rho' wave function contains a significant contribution of
the 3D1 wave which is not consistent with the quark model prediction.Comment: 4 pp, a few short remarks have been added, a reference updated. To
appear in PR
Laser Doppler Velocity & Vorticity Measurements in Turbulent Shear Layers
A Laser Doppler Velocimeter (LDV) system was developed to measure the instantaneous spanwise vorticity, - ω_z, in a turbulent shear layer. It was necessary to design and fabricate the LDV optics and processing electronics, as no commercially available LDV systems met the
specifications of measuring the velocity at four closely spaced points to the requisite accuracy. Measurements were also made of the instantaneous u, v, u', v' and - u'v'. The instantaneous vorticity was processed to obtain an estimate of its probability density function, from which the mean and rms values were estimated. It was also possible to separate the irrotational fraction of the flow (-ω_z = 0)
from the rotational (intermittent) fraction of the flow (-ω_z ≠ O). The development of the intermittency profiles, based on vorticity, as a function of the downstream distance from the splitter plate was studied. A notable feature is that the vorticity is found to have values opposite the mean sense of rotation, i.e., - ω_z(t) < 0, a
significant fraction of the time. Additionally, a detailed study was performed to evaluate the approximation of -∂v/∂x, in terms of various local temporal derivatives ∂v/u(y)∂t. The optimum choice for u(y) can
be found and is influenced by the relative local convection velocities
of the small and large scale structures
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