638 research outputs found
Performance evaluation of a linear predictor frequency estimator for mobile flat fading wireless channels
A well known frequency estimation algorithm using the linear prediction method is analyzed for flat fading wireless channels. The estimator outputs are statistically analyzed and its jitter performances are compared with the non-fading case and the Cramer-Rao bound. We provide a closed form solution for the distribution and the variance of the frequency estimates under fading conditions by making valid assumptions. We also verify the theoretical model using simulations. Analysis shows that the variance of the estimates for flat fading channels reaches a threshold point and increasing the transmit power does not necessarily improve the performances any further
Goiter frequency is more strongly associated with gastric adenocarcinoma than urine iodine level
Purpose: We designed our study to evaluate the hypothesis that gastric cancer is correlated with iodine deficiency or thyroid dysfunction. Materials and Methods: We investigated the total body iodine reserve, thyroid function status and autoimmune disorder in 40 recently diagnosed gastric adenocarcinoma cases versus 80 healthy controls. The participants came from a region with high gastric cancer rate but sufficient iodine supply due to salt iodination. The investigation included urine iodine level, thyroid gland clinical and ultrasonograph-ic examination, and thyroid function tests. Results: Goiter was detected more frequently in the case group (P=0.001); such a finding, however, was not true for lower than normal urine iodine levels. The free T3 mean level was significantly lower in the case group compared to the control group (P=0.005). Conclusions: The higher prevalence of goiter rather than low levels of urinary iodine in gastric adenocarcinoma cases suggests that goi-ter, perhaps due to protracted but currently adjusted iodine deficiency, is more likely to be associated with gastric adenocarcinoma com-pared to the existing iodine deficiency itself. © 2013 by The Korean Gastric Cancer Association
Classifying the unknown: discovering novel gravitational-wave detector glitches using similarity learning
The observation of gravitational waves from compact binary coalescences by
LIGO and Virgo has begun a new era in astronomy. A critical challenge in making
detections is determining whether loud transient features in the data are
caused by gravitational waves or by instrumental or environmental sources. The
citizen-science project \emph{Gravity Spy} has been demonstrated as an
efficient infrastructure for classifying known types of noise transients
(glitches) through a combination of data analysis performed by both citizen
volunteers and machine learning. We present the next iteration of this project,
using similarity indices to empower citizen scientists to create large data
sets of unknown transients, which can then be used to facilitate supervised
machine-learning characterization. This new evolution aims to alleviate a
persistent challenge that plagues both citizen-science and instrumental
detector work: the ability to build large samples of relatively rare events.
Using two families of transient noise that appeared unexpectedly during LIGO's
second observing run (O2), we demonstrate the impact that the similarity
indices could have had on finding these new glitch types in the Gravity Spy
program
Early childhood obesity: a survey of knowledge and practices of physicians from the Middle East and North Africa
BACKGROUND: Childhood obesity is one of the most serious public health issues of the twenty-first century affecting
even low- and middle-income countries. Overweight and obese children are more likely to stay obese into
adulthood. Due to the paucity of data on local practices, our study aimed to assess the knowledge and practices of
physicians from the Middle East and North Africa region with respect to early-onset obesity.
METHODS: A specific questionnaire investigating the perception and knowledge on early-onset obesity was
circulated to healthcare providers (general physicians, pediatricians, pediatric gastroenterologist, neonatologists)
practicing in 17 Middle East and North African countries.
RESULTS: A total of 999/1051 completed forms (95% response) were evaluated. Of all respondents, 28.9% did not
consistently use growth charts to monitor growth during every visit and only 25.2% and 46.6% of respondents
were aware of the correct cut-off criterion for overweight and obesity, respectively. Of those surveyed, 22.3, 14.0,
36.1, 48.2, and 49.1% of respondents did not consider hypertension, type 2 diabetes, coronary heart disease, fatty
liver disease, and decreased life span, respectively, to be a long-term complication of early childhood obesity.
Furthermore, only 0.7% of respondents correctly answered all survey questions pertaining to knowledge of early
childhood overweight and obesity.
CONCLUSION: The survey highlights the low use of growth charts in the evaluation of early childhood growth in
Middle East and North Africa region, and demonstrated poor knowledge of healthcare providers on the short- and
long-term complications of early-onset obesity. This suggests a need for both continued professional education and
development, and implementation of guidelines for the prevention and management of early childhood
overweight and obesity
On the critical behavior of a lattice prey-predator model
The critical properties of a simple prey-predator model are revisited. For
some values of the control parameters, the model exhibits a line of directed
percolation like transitions to a single absorbing state. For other values of
the control parameters one finds a second line of continuous transitions toward
infinite number of absorbing states, and the corresponding steady-state
exponents are mean-field like. The critical behavior of the special point T
(bicritical point), where the two transition lines meet, belongs to a different
universality class. The use of dynamical Monte-Carlo method shows that a
particular strategy for preparing the initial state should be devised to
correctly describe the physics of the system near the second transition line.
Relationships with a forest fire model with immunization are also discussed.Comment: 6 RevTex pages, 7 ps figure
Analysis of symmetries in models of multi-strain infections
In mathematical studies of the dynamics of multi-strain diseases caused by antigenically diverse pathogens, there is a substantial interest in analytical insights. Using the example of a generic model of multi-strain diseases with cross-immunity between strains, we show that a significant understanding of the stability of steady states and possible dynamical behaviours can be achieved when the symmetry of interactions between strains is taken into account. Techniques of equivariant bifurcation theory allow one to identify the type of possible symmetry-breaking Hopf bifurcation, as well as to classify different periodic solutions in terms of their spatial and temporal symmetries. The approach is also illustrated on other models of multi-strain diseases, where the same methodology provides a systematic understanding of bifurcation scenarios and periodic behaviours. The results of the analysis are quite generic, and have wider implications for understanding the dynamics of a large class of models of multi-strain diseases
Effects of Noise on Ecological Invasion Processes: Bacteriophage-mediated Competition in Bacteria
Pathogen-mediated competition, through which an invasive species carrying and
transmitting a pathogen can be a superior competitor to a more vulnerable
resident species, is one of the principle driving forces influencing
biodiversity in nature. Using an experimental system of bacteriophage-mediated
competition in bacterial populations and a deterministic model, we have shown
in [Joo et al 2005] that the competitive advantage conferred by the phage
depends only on the relative phage pathology and is independent of the initial
phage concentration and other phage and host parameters such as the
infection-causing contact rate, the spontaneous and infection-induced lysis
rates, and the phage burst size. Here we investigate the effects of stochastic
fluctuations on bacterial invasion facilitated by bacteriophage, and examine
the validity of the deterministic approach. We use both numerical and
analytical methods of stochastic processes to identify the source of noise and
assess its magnitude. We show that the conclusions obtained from the
deterministic model are robust against stochastic fluctuations, yet deviations
become prominently large when the phage are more pathological to the invading
bacterial strain.Comment: 39 pages, 7 figure
Phase Transitions and Oscillations in a Lattice Prey-Predator Model
A coarse grained description of a two-dimensional prey-predator system is
given in terms of a 3-state lattice model containing two control parameters:
the spreading rates of preys and predators. The properties of the model are
investigated by dynamical mean-field approximations and extensive numerical
simulations. It is shown that the stationary state phase diagram is divided
into two phases: a pure prey phase and a coexistence phase of preys and
predators in which temporal and spatial oscillations can be present. The
different type of phase transitions occuring at the boundary of the prey
absorbing phase, as well as the crossover phenomena occuring between the
oscillatory and non-oscillatory domains of the coexistence phase are studied.
The importance of finite size effects are discussed and scaling relations
between different quantities are established. Finally, physical arguments,
based on the spatial structure of the model, are given to explain the
underlying mechanism leading to oscillations.Comment: 11 pages, 13 figure
Effects of infection-induced migration delays on the epidemiology of avian influenza in wild mallard populations
Wild waterfowl populations form a natural reservoir of Avian Influenza (AI) virus, and fears exist that these birds may contribute to an AI pandemic by spreading the virus along their migratory flyways. Observational studies suggest that individuals infected with AI virus may delay departure from migratory staging sites. Here, we explore the epidemiological dynamics of avian influenza virus in a migrating mallard (Anas platyrhynchos) population with a specific view to understanding the role of infection-induced migration delays on the spread of virus strains of differing transmissibility. We develop a host-pathogen model that combines the transmission dynamics of influenza with the migration, reproduction and mortality of the host bird species. Our modeling predicts that delayed migration of individuals influences both the timing and size of outbreaks of AI virus. We find that (1) delayed migration leads to a lower total number of cases of infection each year than in the absence of migration delay, (2) when the transmission rate of a strain is high, the outbreak starts at the staging sites at which birds arrive in the early part of the fall migration, (3) when the transmission rate is low, infection predominantly occurs later in the season, which is further delayed when there is a migration delay. As such, the rise of more virulent AI strains in waterfowl could lead to a higher prevalence of infection later in the year, which could change the exposure risk for farmed poultry. A sensitivity analysis shows the importance of generation time and loss of immunity for the effect of migration delays. Thus, we demonstrate, in contrast to many current transmission risk models solely using empirical information on bird movements to assess the potential for transmission, that a consideration of infection-induced delays is critical to understanding the dynamics of AI infection along the entire flyway.<br /
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