The core flux of the brightest 10 micron galaxies in the southern sky

Aims. Near diffraction-limited images have been taken at 8.9, 11.9, and 12.9 micron for the brightest extragalactic sources in the southern sky, in order to optimally plan N-band observations with MIDI (MID-infrared Interferometric instrument) at the VLTI. Methods. We have assembled a sample of 21 objects consisting of all the AGNs observable from Paranal observatory, Chile, plus three non-AGN objects, with an estimated N-band flux greater than 400mJy. We used the TIMMI2 Mid Infrared instrument mounted on the ESO's 3.6m telescope to obtain near diffraction-limited images in order to establish the unresolved core flux within < 0.5 arscsec. Results. Positions and core total fluxes were obtained for all sources in our sample and compared with similar investigations in the literature. We find that 15 AGN and the nuclear starburst in NGC 253 exhibit an unresolved core flux < 300mJy at 11.9 micron, making them promising targets for MIDI at the VLTI. For extended sources, near diffraction-limited images are presented and discussed.Comment: Accepted to A&

Parsec-scale dust distributions in Seyfert galaxies - Results of the MIDI AGN snapshot survey

The emission of warm dust dominates the mid-infrared spectra of active galactic nuclei (AGN). Only interferometric observations provide the necessary angular resolution to resolve the nuclear dust and to study its distribution and properties. The investigation of dust in AGN cores is hence one of the main science goals for the MID-infrared Interferometric instrument MIDI at the VLTI. As the first step, the feasibility of AGN observations was verified and the most promising sources for detailed studies were identified. This was carried out in a "snapshot survey" with MIDI using Guaranteed Time Observations. In the survey, observations were attempted for 13 of the brightest AGN in the mid-infrared which are visible from Paranal. The results of the three brightest, best studied sources have been published in separate papers. Here we present the interferometric observations for the remaining 10, fainter AGN. For 8 of these, interferometric measurements could be carried out. Size estimates or limits on the spatial extent of the AGN-heated dust were derived from the interferometric data of 7 AGN. These indicate that the dust distributions are compact, with sizes on the order of a few parsec. The derived sizes roughly scale with the square root of the luminosity in the mid-infrared, s ~ sqrt(L), with no clear distinction between type 1 and type 2 objects. This is in agreement with a model of nearly optically thick dust structures heated to T ~ 300 K. For three sources, the 10 micron feature due to silicates is tentatively detected either in emission or in absorption. Based on the results for all AGN studied with MIDI so far, we conclude that in the mid-infrared the differences between individual galactic nuclei are greater than the generic differences between type 1 and type 2 objects.Comment: 18 pages, 8 figures, updated to version published in A&A 502, 67-8

Selenium Deficiency Is Associated with Mortality Risk from COVID-19

SARS-CoV-2 infections underlie the current coronavirus disease (COVID-19) pandemic and are causative for a high death toll particularly among elderly subjects and those with comorbidities. Selenium (Se) is an essential trace element of high importance for human health and particularly for a well-balanced immune response. The mortality risk from a severe disease like sepsis or polytrauma is inversely related to Se status. We hypothesized that this relation also applies to COVID-19. Serum samples (n = 166) from COVID-19 patients (n = 33) were collected consecutively and analyzed for total Se by X-ray fluorescence and selenoprotein P (SELENOP) by a validated ELISA. Both biomarkers showed the expected strong correlation (r = 0.7758, p < 0.001), pointing to an insufficient Se availability for optimal selenoprotein expression. In comparison with reference data from a European cross-sectional analysis (EPIC, n = 1915), the patients showed a pronounced deficit in total serum Se (mean ± SD, 50.8 ± 15.7 vs. 84.4 ± 23.4 µg/L) and SELENOP (3.0 ± 1.4 vs. 4.3 ± 1.0 mg/L) concentrations. A Se status below the 2.5th percentile of the reference population, i.e., [Se] < 45.7 µg/L and [SELENOP] < 2.56 mg/L, was present in 43.4% and 39.2% of COVID samples, respectively. The Se status was significantly higher in samples from surviving COVID patients as compared with non-survivors (Se; 53.3 ± 16.2 vs. 40.8 ± 8.1 µg/L, SELENOP; 3.3 ± 1.3 vs. 2.1 ± 0.9 mg/L), recovering with time in survivors while remaining low or even declining in non-survivors. We conclude that Se status analysis in COVID patients provides diagnostic information. However, causality remains unknown due to the observational nature of this study. Nevertheless, the findings strengthen the notion of a relevant role of Se for COVID convalescence and support the discussion on adjuvant Se supplementation in severely diseased and Se-deficient patients

Resolving the complex structure of the dust torus in the active nucleus of the Circinus galaxy

To test the dust torus model for active galactic nuclei directly, we study the extent and morphology of the nuclear dust distribution in the Circinus galaxy using high resolution interferometric observations in the mid-infrared with the MIDI instrument at the Very Large Telescope Interferometer. We find that the dust distribution in the nucleus of Circinus can be explained by two components, a dense and warm disk-like component of 0.4 pc size and a slightly cooler, geometrically thick torus component with a size of 2.0 pc. The disk component is oriented perpendicular to the ionisation cone and outflow and seems to show the silicate feature at 10 micron in emission. It coincides with a nuclear maser disk in orientation and size. From the energy needed to heat the dust, we infer a luminosity of the accretion disk corresponding to 20% of the Eddington luminosity of the nuclear black hole. We find that the interferometric data are inconsistent with a simple, smooth and axisymmetric dust emission. The irregular behaviour of the visibilities and the shallow decrease of the dust temperature with radius provide strong evidence for a clumpy or filamentary dust structure. We see no evidence for dust reprocessing, as the silicate absorption profile is consistent with that of standard galactic dust. We argue that the collimation of the ionising radiation must originate in the geometrically thick torus component. Our findings confirm the presence of a geometrically thick, torus-like dust distribution in the nucleus of Circinus, as required in unified schemes of Seyfert galaxies. Several aspects of our data require that this torus is irregular, or "clumpy".Comment: 20 pages, 16 figures, accepted for publication by A&

Profiling complex word usage in the speech of English preschool children: frequency patterns and transparency characteristics

This corpus-based study provides a baseline of complex word usage patterns in the spontaneous speech of English preschool children to ascertain the characteristics of their derivative vocabulary before literacy development affects language skills. Frequencies of suffixed derivatives produced by (N=243) children aged 2-5 and their caregivers were extracted for 58 suffix variants, yielding 558 types from the former and 1,364 from the latter. Between the youngest and oldest groups, 11 suffix categories increased significantly in type frequency, compared with 22 in the caregiver dataset. All derivative types were classified for transparency of meaning and simplicity of form on a 5-point analysability scale. Around 59% of both the child and caregiver derivative vocabulary sets were classified as transparent regardless of age, suggesting that the potential analysability of the preschool child’s input remains surprisingly invariant over time. The study provides baseline data for future studies on the development of morphological awareness in English-speaking schoolchildren

Sub-millimeter to centimeter excess emission from the Magellanic Clouds. I. Global spectral energy distribution

In order to reconstruct the global SEDs of the Magellanic Clouds over eight decades in spectral range, we combined literature flux densities representing the entire LMC and SMC respectively, and complemented these with maps extracted from the WMAP and COBE databases covering the missing the 23--90 GHz (13--3.2 mm) and the poorly sampled 1.25--250 THz (240--1.25 micron). We have discovered a pronounced excess of emission from both Magellanic Clouds, but especially the SMC, at millimeter and sub-millimeter wavelengths. We also determined accurate thermal radio fluxes and very low global extinctions for both LMC and SMC. Possible explanations are briefly considered but as long as the nature of the excess emission is unknown, the total dust masses and gas-to-dust ratios of the Magellanic Clouds cannot reliably be determined.Comment: Accepted for publication by A&

What was Progressive in ‘Progressive Conservatism’?

In January 2009 David Cameron announced that the ‘underlying philosophy’ of his government would be progressive conservatism. Despite the ambiguity about this term, it was generally interpreted as a signal that Cameron was moving his party to the left.To some commentators, Cameron was allying with the progressive ‘one nation’ strand of conservative thought.To others, particularly in the media, he was drawing on the more immediate influence of Phillip Blond’s ‘Red Toryism’. However, the focus on the market (as opposed to state or community) found in both Cameron’s speech and subsequent policies sits uneasily with both of these interpretations. Cameron’s progressive conservatism has more in common with Thatcherism – an earlier conservative modernising project – than it does with centrist forms of conservative progressivism. Cameron’s progressive conservatism is progressive, but only in particular, less commonly used, ways – not as a rediscovery of social justice

The effects of an area-based intervention on the uptake of maternal and child health assessments in Australia: A community trial

Background Recognition of the importance of the early years in determining health and educational attainment and promotion of the World Health Organization Health for All (HFA) principles has led to an international trend towards community-based initiatives to improve developmental outcomes among socio-economically disadvantaged children. In this study we examine whether, Best Start, an Australian area-based initiative to improve child health was effective in improving access to Maternal and Child Health (MCH) services. Methods The study compares access to information, parental confidence and annual 3.5 year Ages and Stages visiting rates before (2001/02) and after (2004/05) the introduction of Best Start. Access to information and parental confidence were measured in surveys of parents with 3 year old children. There were 1666 surveys in the first wave and 1838 surveys in the second wave. The analysis of visiting rates for the 3.5 year Ages and Stages visit included all eligible Victorian children. Best Start sites included 1,739 eligible children in 2001/02 and 1437 eligible children in 2004/05. The comparable figures in the rest of the state were and 45, 497 and 45, 953 respectively. Results There was a significant increase in attendance at the 3.5 year Ages and Stages visit in 2004/05 compared to 2001/02 in all areas. However the increase in attendance was significantly greater at Best Start sites than the rest of the state. Access to information and parental confidence improved over the course of the intervention in Best Start sites with MCH projects compared to other Best Start sites. Conclusion These results suggest that community-based initiatives in disadvantaged areas may improve parents' access to child health information, improve their confidence and increase MCH service use. These outcomes suggest such programmes could potentially contribute to strategies to reduce child health inequalities