773 research outputs found

    Revisitasi Islam Politik dan Islam Kultural di Indonesia

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    This article discusses two faces of Islam, political and cultural, which have developed throughout the Muslim world, including in Indonesia. It argues that political Islam has two faces and both of which, although represented by two different groups, have the same agendas, i.e., the application by the state of shari'a, and also the establishment of Islamic state. Arguing that political Islam has brought about radicalism, the article proposes that the other face of Islam, that is cultural Islam, should be maintained and empowered

    Factors determining the pattern of the variant Creutzfeldt-Jakob disease (vCJD) epidemic in the UK.

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    Following the emergence of a new variant of Creutzfeldt-Jakob disease (vCJD) 6 years ago, and the gradual rise in clinical cases, there has been increased speculation regarding the overall magnitude of this epidemic in Great Britain. In this paper, we explore the epidemiological factors and uncertainties determining the scale of this epidemic in light of the most recent data on reported vCJD mortality. Our results demonstrate that, while the magnitude of the uncertainty has decreased dramatically since 1996, it is still not possible to predict with any degree of accuracy the final magnitude of this epidemic, with the 95% confidence interval for future cases being from 10 to 7000 deaths. However, short-term projections show that it is unlikely that a dramatic increase in case numbers will be observed in the next 2-5 years (95% confidence interval for 2 years: 10-80 cases, for 5 years: 10-200 cases). The results confirm significant age-dependent susceptibility/exposure to infection, with the likelihood profile demonstrating that those aged between 10 and 20 years are at highest risk of infection. We also demonstrate how projections based on onset data may be substantially biased, and explore the sensitivity of results to assumptions concerning the exposure to bovine spongiform encephalopathy (BSE) and the incubation-period distribution

    Faktor-faktor Yang Berhubungan Dengan Status Anemia Ibu Hamil Di Wilayah Kerja Puskesmas Air Dingin Kecamatan Koto Tangah, Kota Padang

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    Latar Belakang : Anemia pada kehamilan saat ini masih menjadi masalah utama yang diderita oleh hampir separuh wanita hamil di seluruh negara di dunia, termasuk Indonesia. Anemia pada kehamilan merupakan ā€œpotential danger to mother and childā€ (potensial membahayakan ibu dan anak). Secara umum, penyebab utama anemia kehamilan adalah kekurangan zat besi yang timbul sebagai akibat dari peningkatan penggunaan zat besi untuk janin. Tujuan : menilai faktor-faktor yang hubungan dengan status anemia pada ibu hamil di wilayah kerja Puskesmas Air Dingin, Kecamatan Kota Tangah, Kota Padang. Metode : Jenis penelitian ini Cross sectional. Alat pengumpul data yang digunakan adalah melalui pengisian kuesioner dan sampel diambil dengan cara Simple Random Sampling. Penelitian ini dilaksanakan pada bulan Aprilā€“ Mei tahun 2014 yang bertempat di Kecamatan Wilayah Kerja Puskesmas Air Dingin Koto Tangah Kota Padang. Pengolahan dan analisis data dilakukan dengan SPSS versi 16 data di analisa univariat dan bivariat dengan Uji Chi-Square pada tingkat kemaknaan 0,05. Hasil : Sebesar 69,4 persen ibu hamil mengalami anemia. Uji chi square menunjukkan hubungan bermakna antara umur kehamilan, suplementasi tablet besi, dan konsumsi (protein, lemak, vitamin c, dan zat besi) terhadap status anemia pada ibu hamil. Kesimpulan : Pencegahan anemia pada ibu hamil dilakukan dengan meningkatkan konsumsi zat gizi dan peningkatan pengetahuan melalui promosi kesehatan ibu hamil mengenai anemia

    Identification of individuals with gonorrhoea within sexual networks: a population-based study.

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    BACKGROUND: Molecular typing of Neisseria gonorrhoeae and contact tracing provide a combined approach for analysis of sexual networks in metropolitan areas, although there are some difficulties in application. Our aim was to examine the application of high-throughput molecular approaches that can identify individuals in linked sexual networks. METHODS: We characterised 2045 isolates of N gonorrhoeae from patients presenting at 13 major sexually transmitted infection clinics in London, UK, between June 1 and Nov 30, 2004. All isolates were assigned a sequence type (strain) on the basis of the sequences of internal fragments of two highly polymorphic loci, por and tbpB. These types were matched to demographic and behavioural data obtained at the clinic for each patient. We assessed the congruence in the demographic and behavioural characteristics of individuals infected with the same strain. FINDINGS: We identified 21 prevalent strains in this diverse gonococcal population, each infecting between 20 and 124 individuals. Seven of these strains were predominantly from men who have sex with men; the remaining 14 were predominantly from heterosexual people. No differences were recorded between the strains associated with men who have sex with men in the demographic or behavioural characteristics of infected individuals. By contrast, significant differences in age (p<0.0001), ethnicity (p=0.001), proportion of women (p=0.01), and HIV status (p=0.03) were noted between the 14 prevalent heterosexual-associated strains. Heterosexuals with strains not shared by others in the sample were significantly older (p=0.0005) and more likely to have had sex outside the UK (p<0.0001) than those sharing a strain with at least one other. INTERPRETATION: The discriminatory high throughput strain characterisation method applied here identified localised transmission networks and suggests little bridging between networks of men who have sex with men and heterosexual networks

    Effect of multiple micronutrient supplementation during pregnancy on maternal and birth outcomes

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    <p>Abstract</p> <p>Objectives/background</p> <p>Given the widespread prevalence of micronutrient deficiencies in developing countries, supplementation with multiple micronutrients rather than iron-folate alone, could be of potential benefit to the mother and the fetus. These benefits could relate to prevention of maternal complications and reduction in other adverse pregnancy outcomes such as small-for-gestational age (SGA) births, low birth weight, stillbirths, perinatal and neonatal mortality. This review evaluates the evidence of the impact of multiple micronutrient supplements during pregnancy, in comparison with standard iron-folate supplements, on specific maternal and pregnancy outcomes of relevance to the Lives Saved Tool (LiST).</p> <p>Data sources/review methods</p> <p>A systematic review of randomized controlled trials was conducted. Search engines used were PubMed, the Cochrane Library, the WHO regional databases and hand search of bibliographies. A standardized data abstraction and Child Health Epidemiology Reference (CHERG) adaptation of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) technique were used for data abstraction and overall quality of evidence. Meta-analyses were performed to calculate summary estimates of utility to the LiST model for the specified outcome of incidence of SGA births. We also evaluated the potential impact of multiple micronutrients on neonatal mortality according to the proportion of deliveries occurring in facilities (using a threshold of 60% to indicate functionality of health systems for skilled births).</p> <p>Results</p> <p>We included 17 studies for detailed data abstraction. There was no significant benefit of multiple micronutrients as compared to iron folate on maternal anemia in third trimester [Relative risk (RR) = 1.03; 95% confidence interval (CI): 0.87 ā€“ 1.22 (random model)]. Our analysis, however, showed a significant reduction in SGA by 9% [RR = 0.91; 95% CI: 0.86 ā€“ 0.96 (fixed model)]. In the fixed model, the SGA outcome remained significant only in women with mean body mass index (BMI) ā‰„ 22 kg/m<sup>2</sup>. There was an increased risk of neonatal mortality in studies with majority of births at home [RR = 1.47, 95% CI: 1.13-1.92]; such an effect was not evident where ā‰„ 60% of births occurred in facility settings [RR = 0.94, 95% CI: 0.81-1.09]. Overall there was no increase in the risk of neonatal mortality [RR = 1.05, 95% CI: 0.92 ā€“ 1.19 (fixed model)].</p> <p>Conclusion</p> <p>This review provides evidence of a significant benefit of MMN supplementation during pregnancy on reducing SGA births as compared to iron-folate, with no significant increase in the risk of neonatal mortality in populations where skilled birth care is available and majority of births take place in facilities. Given comparability of impacts on maternal anemia, the decision to replace iron-folate with multiple micronutrients during pregnancy may be taken in the context of available services in health systems and birth outcomes monitored.</p

    Unlocking the Potential of Polythioesters

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    As the demand for sustainable polymers increases, most research efforts have focused on polyesters, which can be bioderived and biodegradable. Yet analogous polythioesters, where one of the oxygen atoms has been replaced by a sulfur atom, remain a relatively untapped source of potential. The incorporation of sulfur allows the polymer to exhibit a wide range of favorable properties, such as thermal resistance, degradability, and high refractive index. Polythioester synthesis represents a frontier in research, holding the promise of paving the way for eco-friendly alternatives to conventional polyesters. Moreover, polythioester research can also open avenues to the development of sustainable and recyclable materials. In the last 25 years, many methods to synthesize polythioesters have been developed. However, to date no industrial synthesis of polythioesters has been developed due to challenges of costs, yields, and the toxicity of the by-products. This review will summarize the recent advances in polythioester synthesis, covering step-growth polymerization, ring-opening polymerization (ROP), and biosynthesis. Crucially, the benefits and challenges of the processes will be highlighted, paying particular attention to their sustainability, with the aim of encouraging further exploration and research into the fast-growing field of polythioesters

    Chromium stress in Brassica juncea L. cv. 'Pusa Jai Kissan' under hydroponic culture

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    Chromium (Cr) entering plant tissue inhibits most physiological processes at all levels of metabolism including inhibition of growth, photosynthesis and nitrate assimilation. Since Cr exists in many forms, its toxicity to plants depends on its valence state, with Cr (VI) found to be highly toxic and mobile than Cr (III). Different concentrations of Cr (0, 25, 50 and 100 Ī¼M) in the form of K2Cr2O7 was added to 30 days old Brassica juncea plant and harvested on the 3rd and 5th days after treatment for estimation of plant growth, chlorophyll, total soluble protein, free amino acids and nitrate reductase activity. Cr was found to cause deleterious effects on whole plant growth. The potential of plants with the capacity to accumulate or to stabilize Cr compounds for bioremediation of Cr contamination has gained interest in recent years. The biochemical aspects like photosynthetic pigments (Chl a and Chl b), total protein and amino acids content decreased with Cr concentration. A significant increase in nitrate reductase activity was observed corresponding to Cr concentration.Key words: Brassica juncea, chromium, heavy metal, phytoremediation

    Rhodotorula mucilaginosa lymphadenitis in an HIV-infected patient

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    SummaryWe report a case of lymphadenitis due to Rhodotorula mucilaginosa in a man with well-controlled HIV infection. The diagnosis was established microbiologically by positive lymph tissue cultures, and clinically by responses of lymphadenitis to antifungal therapy. The patient was asymptomatic and was treated with itraconazole 200mg orally once daily as an outpatient. Clinical response was evident within three weeks with improvement of lymphadenopathy on serial computed tomography scans. Lymphadenopathy resolved completely after 8 months of itraconazole therapy and had not recurred 9 months after treatment was stopped
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