Onsite Job Scheduling by Adaptive Genetic Algorithm

Onsite Job Scheduling is a specialized variant of Vehicle Routing Problem (VRP) with multiple depots. The objective of this problem is to execute jobs requested by customers, belonging to different geographic locations by a limited number of technicians, with minimum travel and overtime of technicians. Each job is expected to be completed within a specified time limit according to the service level agreement with customers. Each technician is assumed to start from a base location, serve several customers and return to the starting place. Technicians are allotted jobs based on their skill sets, expertise levels of each skill and availability slots. Although there are considerable number of literatures on VRP we do not see any explicit work related to Onsite Job Scheduling. In this paper we have proposed an Adaptive Genetic Algorithm to solve the scheduling problem. We found an optimized travel route for a substantial number of jobs and technicians, minimizing travel distance, overtime duration as well as meeting constraints related to SLA

An Overview of the Genus Nardostachys

Nardostachys jatamansi, a medicinally important herb of Nepalese origin, has been used for centuries in the Ayurvedic and Unani systems of medicine. In combination with Marsilea minuta it is being used as an antistress and anticonvulsant drug and also finds use in the treatment of epilepsy. Recently, it has been reported that N. jatamansi, which plays an important role in protecting from cerebral ischemia and liver damage, is also used for the treatment of osteoporosis and hypercalcemia. The other member of the genus Nardostachys, N. chinensis, possesses antifungal and antimalarial properties. It is also used in the treatment of skin dysfunction. A short summary of the chemical constituents of the two species along with their physical and biological properties is reported

N-(4-Methylphenyl) Benzenepropanamide - the First Isolated Amide From the Genus Paederia

Investigation of the stem of Paederia foetida (Rubiaceae) resulted in the isolation and characterization of N-(4-methylphenyl)-benzopropanamide, which was hitherto unknown as a natural product This is the first report of an amide for the genus Paederia

Use of ninhydrin for detection of silylated amino acids

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A new route to the synthesis of indolo[2,3-a]carbazoles

A straightforward, easy and smooth process of synthesizing indolo[2,3-a]carbazoles, which can frequently serve as a nucleus of several natural products is reported. The process involves only two steps viz. single electron transfer reaction and subsequent reductive cyclization with hydrazine

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An entry to the synthesis of novel nitrogen macroheterocycles

2,2'-Bi(1H-indolyl)-3,3'-dicarbaldehydes, prepared from 1H-indole-3-carbaldehydes by exploiting SET methodology, served as the key compound for synthesizing indolo[2,3-a]carbazoles as well as nitrogen macroheterocycles. Condensation of 2,2'-bi(1H-indolyl)-3,3'-dicarbaldehyde with aliphatic diamines produced Schiff’s base type compounds possessing a 10–14-membered ring

Bilateral tubal pregnancy: A diagnostic dilemma

ABSTRACT Bilateral tubal ectopic pregnancy is very rare and usually occurs following ovulation stimulation. Moreover preoperative diagnosis is very difficult. We are presenting a case of bilateral tubal ectopic pregnancy occurring spontaneously. Hence careful follow-up with combination of color Doppler and serum beta HCG estimation of patients after laparoscopic or open surgery for ectopic pregnancies is needed to avoid such unusual event

Saradaferin, a new sesquiterpenoid coumarin from Ferula assafoetida

Phytochemical investigation of the gum resin of Ferula assafoetida resulted in the isolation and characterization of a new sesquiterpenoid coumarin, Saradaferin named as [Decahydro-(3-α-hydroxy-4,4,10-trimethyl-8-methylene-9-naphthenyl)-α-hydroxymethyl] ether of umbelliferone