236 research outputs found
VLBA polarimetric observations of the CSS quasar 3C147
Aims. We report new VLBA polarimetric observations of the compact
steep-spectrum (CSS) quasar 3C147 (B0538+498) at 5 and 8.4GHz.
Methods. By using multifrequency VLBA observations, we derived
milliarcsecond-resolution images of the total intensity, polarisation, and
rotation measure distributions, by combining our new observations with archival
data.
Results. The source shows a one-sided structure, with a compact region, and a
component extending about 200 mas to the south-west. The compact region is
resolved into two main components with polarised emission, a complex rotation
measure distribution, and a magnetic field dominated by components
perpendicular to the source axis.
Conclusions. By considering all the available data, we examine the possible
location of the core component, and discuss two possible interpretations of the
observed structure of this source: core-jet and lobe-hot spot. Further
observations to unambiguously determine the location of the core would help
distinguish between the two possibilities discussed here.Comment: 11 pages, 12 figure
Resonant Kelvin-Helmholtz modes in sheared relativistic flows
Qualitatively new aspects of the (linear and non-linear) stability of sheared
relativistic (slab) jets are analyzed. The linear problem has been solved for a
wide range of jet models well inside the ultrarelativistic domain (flow Lorentz
factors up to 20; specific internal energies ). As a distinct
feature of our work, we have combined the analytical linear approach with
high-resolution relativistic hydrodynamical simulations, which has allowed us
i) to identify, in the linear regime, resonant modes specific to the
relativistic shear layer ii) to confirm the result of the linear analysis with
numerical simulations and, iii) more interestingly, to follow the instability
development through the non-linear regime. We find that very high-order
reflection modes with dominant growth rates can modify the global, long-term
stability of the relativistic flow. We discuss the dependence of these resonant
modes on the jet flow Lorentz factor and specific internal energy, and on the
shear layer thickness. The results could have potential applications in the
field of extragalactic relativistic jets.Comment: Accepted for publication in Physical Review E. For better quality
images, please check
http://www.mpifr-bonn.mpg.de/staff/mperucho/Research.htm
Interleukin 21 inhibits cancer-mediated FOXP3 induction in naïve human CD4 T cells
IL-21 is known to promote anti-tumour immunity due to its ability to promote T cell responses and counteract Treg-mediated suppression. It has also been shown to limit Treg frequencies during tumour-antigen stimulations. However, whether this represents inhibition of FOXP3 induction in naïve CD4 T cells or curtailed expansion of natural Treg remains unclear. Moreover, whether this effect is maintained in an environment of tumour-derived immunosuppressive factors is not known. Here, we show that in the context of a number of cancers, naïve CD45RA+ CD4 T cells are induced to express high levels of FOXP3, and that FOXP3 expression correlates with inhibition of T cell proliferation. FOXP3 expression was most potently induced by tumours secreting higher levels of total and active TGFβ1 and this induction could be potently counteracted with IL-21, restoring T cell proliferation. We conclude that Treg induction in naïve T cells is a common phenomenon amongst a number of different cancers and that the ability of IL-21 to counteract this effect is further evidence of its promise in cancer therapy
2mm Wavelength VLBI of SiO Masers and AGN
In April 2002 an array of antennas operating at 129GHz successfully detected
VLBI fringes on both continuum AGN and SiO maser sources. The 129GHz fringes on
maser sources represent the highest frequency spectral line VLBI detections to
date. The AGN 3C279 was detected on long baselines at both 129GHz (and at
147GHz, see Krichbaum et al in these proceedings) yielding fringe spacings of
50-56 micro arc seconds, an angular resolution record. The array consisted of
the University of Arizona Kittpeak 12m antenna, the Heinrich Hertz 10m
Telescope (HHT), and the IRAM 30m dish on Pico Veleta.
At 129GHz, a number of evolved stars and several young stellar objects
exhibit strong SiO maser emission in the v=1 J=3-2 transition. Preliminary
cross power spectra of SiO masers around the red hypergiant VYCMa on the
HHT-KittPeak baseline ~190km are consistent with multiple spatially separate
maser spots associated with the star. Future observations will include
continuum observations of the radio source at the Galactic Center, SgrA*, and
higher frequency maser lines including HCN and methanol.Comment: 4 pages, 3 figures, appears in: Proceedings of the 6th European VLBI
Network Symposium held on June 25th-28th in Bonn, Germany. Edited by: E. Ros,
R.W. Porcas, A.P. Lobanov, and J.A. Zensus. New version includes all editors
in paper heade
Fermi Large Area Telescope Observations of Misaligned AGN
Analysis is presented on 15 months of data taken with the Large Area
Telescope (LAT) on the Fermi Gamma-ray Space Telescope for 11 non-blazar AGNs,
including 7 FRI radio galaxies and 4 FRII radio sources consisting of 2 FRII
radio galaxies and 2 steep spectrum radio quasars. The broad line FRI radio
galaxy 3C 120 is reported here as a gamma-ray source for the first time. The
analysis is based on directional associations of LAT sources with radio sources
in the 3CR, 3CRR and MS4 (collectively referred to as 3C-MS) catalogs. Seven of
the eleven LAT sources associated with 3C-MS radio sources have spectral
indices larger than 2.3 and, except for the FRI radio galaxy NGC 1275 that
shows possible spectral curvature, are well described by a power law. No
evidence for time variability is found for any sources other than NGC 1275. The
gamma-ray luminosities of FRI radio galaxies are significantly smaller than
those of BL Lac objects detected by the LAT, whereas the gamma-ray luminosities
of FRII sources are quite similar to those of FSRQs, which could reflect
different beaming factors for the gamma-ray emission. A core dominance study of
the 3CRR sample indicate that sources closer to the jet axis are preferentially
detected with the Fermi-LAT, insofar as the gamma-ray--detected misaligned AGNs
have larger core dominance at a given average radio flux. The results are
discussed in view of the AGN unification scenario.Comment: 28 pages, 8 figures, 2 tables. Accepted for publication in The
Astrophysical Journa
'Caught Between a Rock and a Hard Place': Anti-discrimination Legislation in the Liberal State and the Fate of the Australian Disability Discrimination Act
This article offers a critical analysis of some of the practical implications for disabled people of the Disability Discrimination Act of 1992. Specifically, it raises questions about politics and the role of the law as an instrument of social change?taking greater account of the interests of disabled people?on the one hand, and of the reliance of the social model of disability on a strategy based upon legal rights on the other. The article also suggests that the constraining effects of Australia's constitutional protections of rights and its federal system of government hinder the mildly progressive elements of the Disability Discrimination Act. To illustrate this, the paper employs empirical evidence to suggest that these effects have been exacerbated by the passage of the Human Rights Legislation Amendment Act in 1999
Increasing cognitive inhibition with a difficult prior task:implications for mathematical thinking
Dual-process theories posit two distinct types of cognitive processing: Type 1, which does not use working memory making it fast and automatic, and Type 2, which does use working memory making it slow and effortful. Mathematics often relies on the inhibition of pervasive Type 1 processing to apply new skills or knowledge that require Type 2 processing. In two studies, we demonstrate that giving participants a difficult task (Raven’s Matrices) before a task that requires the inhibition of intuitive responses (the Cognitive Reflection Test) significantly improves performance. Our findings suggest that encountering a difficult task that requires Type 2 processing before completing a task that requires inhibition of Type 1 processing may encourage an enduring ‘Type 2’ mindset, whereby participants are more likely to spontaneously use Type 2 processing for a period of time. Implications for mathematics education are discussed
The Sail-Backed Reptile Ctenosauriscus from the Latest Early Triassic of Germany and the Timing and Biogeography of the Early Archosaur Radiation
Background
Archosaurs (birds, crocodilians and their extinct relatives including dinosaurs) dominated Mesozoic continental ecosystems from the Late Triassic onwards, and still form a major component of modern ecosystems (>10,000 species). The earliest diverse archosaur faunal assemblages are known from the Middle Triassic (c. 244 Ma), implying that the archosaur radiation began in the Early Triassic (252.3–247.2 Ma). Understanding of this radiation is currently limited by the poor early fossil record of the group in terms of skeletal remains.
Methodology/Principal Findings
We redescribe the anatomy and stratigraphic position of the type specimen of Ctenosauriscus koeneni (Huene), a sail-backed reptile from the Early Triassic (late Olenekian) Solling Formation of northern Germany that potentially represents the oldest known archosaur. We critically discuss previous biomechanical work on the ‘sail’ of Ctenosauriscus, which is formed by a series of elongated neural spines. In addition, we describe Ctenosauriscus-like postcranial material from the earliest Middle Triassic (early Anisian) Röt Formation of Waldhaus, southwestern Germany. Finally, we review the spatial and temporal distribution of the earliest archosaur fossils and their implications for understanding the dynamics of the archosaur radiation.
Conclusions/Significance
Comprehensive numerical phylogenetic analyses demonstrate that both Ctenosauriscus and the Waldhaus taxon are members of a monophyletic grouping of poposauroid archosaurs, Ctenosauriscidae, characterised by greatly elongated neural spines in the posterior cervical to anterior caudal vertebrae. The earliest archosaurs, including Ctenosauriscus, appear in the body fossil record just prior to the Olenekian/Anisian boundary (c. 248 Ma), less than 5 million years after the Permian–Triassic mass extinction. These earliest archosaur assemblages are dominated by ctenosauriscids, which were broadly distributed across northern Pangea and which appear to have been the first global radiation of archosaurs
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