2,637 research outputs found
Modular symbols and Hecke operators
We survey techniques to compute the action of the Hecke operators on the
cohomology of arithmetic groups. These techniques can be seen as
generalizations in different directions of the classical modular symbol
algorithm, due to Manin and Ash-Rudolph. Most of the work is contained in
papers of the author and the author with Mark McConnell. Some results are
unpublished work of Mark McConnell and Robert MacPherson.Comment: 11 pp, 2 figures, uses psfrag.st
Successful treatment of jellyfish sting-induced severe digital ischemia with intravenous iloprost infusion
published_or_final_versio
Application of modern control and nonlinear estimation techniques
Control and nonlinear estimation techniques applied to optimal guidance of low thrust spacecraft, planetary soft landings, and feedback systems desig
Effect of micronutrient fortified beverage on nutritional anaemia during pregnancy
(East African Medical Journal: 2002 79 (11): 598-603
An electromyographic study of jaw opening and closing reflexes in man
The electromyographic activity of the right masseter and digastric muscles was recorded in 10 subjects. A jaw-opening reflex was observed shortly after a mechanical stimulation in subjects performing clenching and active jaw-opening exercises. The latency of this reflex activity was about 28 ms, coinciding with the termination of the silent period of the masseter muscle. The experiments show that this opening reflex can occur without masseter spindle-unloading and may respond to low-threshold afferents.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/24082/1/0000336.pd
A scoping review of burden of disease studies estimating disability-adjusted life years due to Taenia solium
Background
Taenia solium is the most significant global foodborne parasite and the leading cause of preventable human epilepsy in low and middle-income countries in the form of neurocysticercosis.
Objectives
This scoping review aimed to examine the methodology of peer-reviewed studies that estimate the burden of T. solium using disability-adjusted life years.
Eligibility criteria
Studies must have calculated disability-adjusted life years relating to T. solium.
Charting methods
The review process was managed by a single reviewer using Rayyan. Published data relating to disease models, data sources, disability-adjusted life years, sensitivity, uncertainty, missing data, and key limitations were collected.
Results
15 studies were included for review, with seven global and eight national or sub-national estimates. Studies primarily employed attributional disease models that relied on measuring the occurrence of epilepsy before applying an attributable fraction to estimate the occurrence of neurocysticercosis-associated epilepsy. This method relies heavily on the extrapolation of observational studies across populations and time periods; however, it is currently required due to the difficulties in diagnosing neurocysticercosis. Studies discussed that a lack of data was a key limitation and their results likely underestimate the true burden of T. solium. Methods to calculate disability-adjusted life years varied across studies with differences in approaches to time discounting, age weighting, years of life lost, and years of life lived with disability. Such differences limit the ability to compare estimates between studies.
Conclusions
This review illustrates the complexities associated with T. solium burden of disease studies and highlights the potential need for a burden of disease reporting framework. The burden of T. solium is likely underestimated due to the challenges in diagnosing neurocysticercosis and a lack of available data. Advancement in diagnostics, further observational studies, and new approaches to parameterising disease models are required if estimates are to improve
A planar respiration sensor based on a capaciflector structure
Respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), affect more than 300 million people worldwide. Devices such as the pneumotachograph are currently used within a clinical environment for measuring the inhalation, expiration, and respiration cycle but are physically large and not suitable for home use by patients. A small, lightweight respiration sensor for use in the home environment allows patients to monitor respiratory rate in a simple manner. The capaciflector was originally developed by NASA as a capacitive proximity sensor for collision detection in robots. We have found that the device can also be used to detect breathing patterns in humans by attaching it to the chest. In this article, we discuss the simulation, construction, and testing of a capaciflector for use as a respiration sensor and describe how it can be interfaced to a microcontroller in order to allow us wireless data transmission over a Wi-Fi signal
Rapid Quantification of Molecular Diversity for Selective Database Acquisition
There is an increasing need to expand the structural diversity of the molecules investigated in lead-discovery programs. One way in which this can be achieved is by acquiring external datasets that will enhance an existing database. This paper describes a rapid procedure for the selection of external datasets using a measure of structural diversity that is calculated from sums of pairwise intermolecular structural similarities
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