Crystallization of the immunodominant outer membrane protein OmpC; the first protein crystals from Salmonella typhi, a human pathogen

AbstractOmpC, a surface antigen of Salmonella typhi was crystallized after several attempts, using PEG 3350. Well shaped hexagonal crystals were grown from vapor diffusion method using octyl glucoside and C12E9 as detergents. Crystals are sensitive to X-ray and diffract weakly up to 7 Å. Porin isoforms, due to the bound lipopolysaccharides, could be the cause for poor diffraction. Crystal quality depends largely on the purification method, and in case of LPS contamination, the genetic background of the bacteria. Crystallization and initial data collection suggest optimum conditions and the method of choice for OmpC crystallization

A note on a fixed point theorem for ray oriented maps

[EN] In this paper, we will prove a fixed point theorem for a ray-oriented map defined on a nonempty closed bounded convex subset of a Banach space.Arockiasamy, A.; Eldred, A. (2008). A note on a fixed point theorem for ray oriented maps. Applied General Topology. 9(2):185-188. doi:10.4995/agt.2008.1798.SWORD1851889

Information and attitudes of Women Doctors towards ICT and Digital Resources

Using information and communication technology (ICT) means communicating, creating, distributing and managing data. There is no sector of society that does not benefit from the use of information and communication technology. Covid-19 epidemic necessitates the repurposing of ICT systems intended for other distributed purposes to retain social connections, deliver distributed services, and fulfil corporate needs. Next to the IT field, the paradigm shift takes place in the medical field. During the pandemic situation, the usage of ICT tremendously increased in all departments of the medical field. In this situation, the research analyses women doctors\u27 attitudes towards ICT and digital resources for understanding their acceptance. The study\u27s objective is to identify how women Doctors use ICT products and applications. To decide the familiarity of ICT products and applications among women Doctors. To find the frequency of using ICT based health knowledge by the women doctors. Research design and sites used a cross-sectional investigation strategy. Few medical women doctors in government hospitals and private hospitals in Tirunelveli city contributed. The sample size of the study was restricted to 62 in numbers. Secondary data was also used for further information. Descriptive analysis methods, partial correlation and ANOVA tests are used as analytical tools for this study