2,492 research outputs found

    Te puse la mano en el hombro 'I put my hand on your shoulder' : A solution to a puzzling constraint on multiple external possession relations in Spanish

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    The main goal of this paper is to provide a solution to a puzzle regarding a constraint on multiple external possession relations in Spanish prepositional double object verbs like poner 'put.' When both the direct object and prepositional object are body parts with different external possessors, the subject must be the possessor of the direct object body part and a dative clitic the possessor the prepositional object body part, not the other way around. Assuming that possessor movement to theta positions is what gives rise to external possession, I claim that the unacceptable interpretation is due to a locality violation that is incurred when an external possession relation is established between a subject and prepositional object body part that crosses over another external possession relation between a dative clitic and direct object body part

    Framing hate: Moral foundations, party cues, and (In)tolerance of offensive speech

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    Ā© 2017, PsychOpen. All rights reserved. One of the most controversial elements of political tolerance concerns support for hate speech. We argue that there are two factors that can reduce tolerance for hate speech: 1) moral foundations and 2) party cues. U.S. citizensā€™ tolerance of hate speech will be reduced when it is framed as a violation of a specific moral foundation, opposed by a political party, or when the morality violation is utilized by party elites. Using two survey experiments, we manipulated the target of hate speech (i.e. Muslims or the American flag), whether the speech violated a moral foundation (i.e. harm or loyalty), and which political party supported or opposed the hate speech in question. For flag burning, moral frames and party cues on their own reduced U.S. citizensā€™ tolerance relative to a non-political control, while moral frames and party cues were successful in reducing tolerance of anti-Muslim speech compared to a free speech appeal. Partisans were generally responsive to cues from the in-party. We also found instances of moral repackaging, where morally incongruent appeals from the in-party reduced tolerance of flag burning among Democrats. Among Republicans, harm morality decreased tolerance of anti-Muslim speech when invoked by the in-party, but increased tolerance when used by the out-party ā€“ an indication of the power of party cues to repackage moral arguments and to trigger backlash. These results provide a better understanding of what factors can affect tolerance for hate speech, providing political leaders and social justice advocates with a roadmap to alleviate this problem

    Elbow flexor strength, muscle size, and moment arms in prepubertal boys and girls

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    Copyright Ā© 2006 Human Kinetics.The aim of this study was to examine elbow flexion torque, muscle cross-sectional area (CSA), and leverage in boys and girls. Thirty-eight prepubertal children (9.6 Ā± 0.3 years) volunteered to participate. All performed isometric flexion actions at 10Ā°, 50Ā°, and 90Ā° of elbow flexion. Magnetic resonance imaging was used to assess elbow flexor (EF) muscle CSA and brachialis moment arm lengths. No significant gender differences were observed for any of the variables studied. EF CSA was directly proportional to isometric torque at 50Ā° and 90Ā°. CSA explained between 47% and 57% of torque variance. Moment arm estimates explained 19% of the variance in isometric torque at 90Ā°. These baseline data contribute to our understanding of factors influencing strength variation during childhood

    Examining the Parent-child Political Relationship

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    The purpose of this study is to provide a detailed explanation of the ability of parents to transmit political attitudes to their children. While there is an abundance of previous research on political socialization and the role of parents in this process, this study's incorporation of novel variables allows a different and contemporary exploration of the political development of youth. Using a survey of 955 college students, I am able to provide evidence that the political influence of parents is strong, level of parental involvement is highly important, and mothers are slightly more influential than fathers, but not as much as previously accepted.Political Scienc

    Spino-olivary projections in the rat are anatomically separate from postsynaptic dorsal column projections.

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    The gracile nucleus (GN) and lateral part of rostral dorsal accessory olive (rDAO) are important relays for indirect, postsynaptic dorsal column, and direct ascending pathways, respectively, that terminate as climbing fibers in the "hindlimb-receiving" parts of the C1 and C3 zones in the cerebellar cortex. While the spinal cells of origin of that project to GN and rDAO are from largely separate territories in the spinal cord, previous studies have indicated that there could be an area of overlap between these two populations in the medial dorsal horn. Given the access of these two ascending tracts to sensory (thalamic) versus sensorimotor (precerebellar) pathways, the present study therefore addresses the important question of whether or not individual neurons have the potential to contribute axons to both ascending pathways. A double-fluorescent tracer strategy was used in rats (red Retrobeads and Fluoro-Ruby or green Retrobeads and Fluoro-Emerald) to map the spatial distribution of cells of origin of the two projections in the lumbar spinal cord. The two pathways were found to receive input from almost entirely separate territories within the lumbar cord (levels L3-L5). GN predominantly receives input from lamina IV, while rDAO receives its input from three cell populations: medial laminae V-VI, lateral lamina V, and medial laminae VII-VIII. Cells that had axons that branched to supply both GN and rDAO represented only about 1% of either single-labeled cell population. Overall, the findings therefore suggest functional independence of the two ascending pathways

    A gap in the mass distribution for warm Neptune and terrestrial planets

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    Structure in the planet distribution provides an insight into the processes that shape the formation and evolution of planets. The Kepler mission has led to an abundance of statistical discoveries in regards to planetary radius, but the number of observed planets with measured masses is much smaller. By incorporating results from recent mass determination programs, we have discovered a new gap emerging in the planet population for sub-Neptune-mass planets with orbital periods less than 20 days. The gap follows a slope of decreasing mass with increasing orbital period, has a width of a few M āŠ•, and is potentially completely devoid of planets. Fitting Gaussian mixture models to the planet population in this region favors a bimodel distribution over a unimodel one with a reduction in Bayesian information criterion of 19.9, highlighting the gap significance. We discuss several processes that could generate such a feature in the planet distribution, including a pileup of planets above the gap region, tidal interactions with the host star, dynamical interactions with the disk, with other planets, or with accreting material during the formation process

    G2Cdb: the Genes to Cognition database

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    Neuroscience databases linking genes, proteins, (patho)physiology, anatomy and behaviour across species will be valuable in a broad range of studies of the nervous system. G2Cdb is such a neuroscience database aiming to present a global view of the role of synapse proteins in physiology and disease. G2Cdb warehouses sets of genes and proteins experimentally elucidated by proteomic mass spectroscopy of signalling complexes and proteins biochemically isolated from mammalian synapse preparations, giving an experimentally validated definition of the constituents of the mammalian synapse. Using automated text-mining and expert (human) curation we have systematically extracted information from published neurobiological studies in the fields of synaptic signalling electrophysiology and behaviour in knockout and other transgenic mice. We have also surveyed the human genetics literature for associations to disease caused by mutations in synaptic genes. The synapse proteome datasets that G2Cdb provides offer a basis for future work in synapse biology and provide useful information on brain diseases. They have been integrated in a such way that investigators can rapidly query whether a gene or protein is found in brain-signalling complex(es), has a phenotype in rodent models or whether mutations are associated with a human disease. G2Cdb can be freely accessed at http://www.genes2cognition.org

    Long-term persistency and costs associated with the use of iron chelation therapies in the treatment of Sickle cell disease within Medicaid programs.

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    OBJECTIVE: This retrospective study evaluated iron chelating therapy (ICT) discontinuation and costs in Sickle cell disease (SCD) Medicaid recipients using healthcare claims from 2006-2010. METHODS: Patients with ā‰„1 SCD diagnosis claim, ā‰„2 claims for deferoxamine (DFO) or deferosirox (DFX), and continuous enrollment ā‰„6 months prior to and 18 months following ICT initiation were included. Outcomes included treatment discontinuation, persistence (i.e., refill gaps ā‰„6 weeks), and total healthcare costs. RESULTS: The average age among 404 SCD patients meeting study inclusion criteria was 18.7 (Ā±11.0) years, with 45.8% being males and 66.7% being Blacks. Switches or combinations from DFO at index occurred in 124 (74.7%) patients compared to 10 (4.2%) with DFX at index. The Cox regression model that assessed long-term medication persistence indicated a 1.30-times higher likelihood of treatment discontinuation with DFO compared to DFX (95% CI: 1.06-1.61). Some 19.7% of patient remained on DFX relative to 4.8% on DFO. Both inpatient and total costs were similar in DFX and DFO treatment groups. Following 1 year of treatment, 37.4% remained on DFX compared to 15.7% on DFO. Meaningful differences in treatment discontinuation between the two treatment groups did not occur until 220+ days during the study period. At 18-months, treatment discontinuation rates were high in both groups; 95% for DFO and 80% for DFX. CONCLUSION: This study of SCD Medicaid patients found more therapeutic switches from DFO to DFX and a higher medication persistency rate with DFX than DFO. The conclusions are limited by the study\u27s retrospective nature, which depends on multivariate statistics to account for patient heterogeneity and risk factors
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