Atributos físicos e químicos de argissolo amarelo sob cultivo orgânico.

A utilização de sistemas orgânicos de produção agrícola tem ganhado destaque no cenário mundial principalmente devido à busca por alimentos de maior qualidade, mas também por outros benefícios como a conservação/melhoria de características físicas, químicas e biológicas do solo, aliada ao menor impacto ambiental. O presente trabalho propõe a avaliar a qualidade física e química de um Argissolo após dois anos de cultivo orgânico de videira de vinho, tendo como referência uma área de pousio. A avaliação se deu através da análise da estabilidade de agregados, dos cálculos dos índices de e de dispersão floculação do solo, da densidade do solo e do teor de carbono orgânico, a partir de amostras coletadas nas linhas e entrelinhas da videira e área de pousio, nas profundidades de 0-0,10, 0,10-0,20; 0,20-0,30 m e 0,30-0,60 m. Observou-se que o sistema influenciou a agregação do solo; o manejo nas linhas com a implantação de coquetéis vegetais possivelmente elevou o conteúdo de matéria orgânica quando comparado à entrelinha e pousio; e foram encontrados maiores teores dos elementos Mg e Ca na área de pousio e na linha de plantio, o mesmo não ocorrendo para K e Na

Cortisol modulation by ayahuasca in patients with treatment resistant depression and healthy controls

Major depression is a highly prevalent mood disorder, affecting about 350 million people, and around 30% of the patients are resistant to currently available antidepressant medications. Recent evidence from a randomized controlled trial (RCT) supports the rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression. The aim of this study was to explore the effect of ayahuasca on plasma cortisol and awakening salivary cortisol response, in the same group of treatment-resistant patients (MD) and in healthy volunteers (C). Subjects received a single dose of ayahuasca or placebo (dosing session), and both plasma and awakening salivary cortisol response were measured at baseline (before dosing session) and 48 h after the dosing session. Baseline assessment (D0) showed blunted awakening salivary cortisol response and hypocortisolemia in patients, with respect to healthy controls. Salivary cortisol was also measured during dosing session, and we observed higher increases for both C and MD that ingested ayahuasca than placebo. After 48 h from the dosing session with ayahuasca, patients' awakening salivary cortisol response is similar to the ones detected in controls. No significant changes in plasma cortisol levels were observed 48 h after the sessions. Therefore, these findings point to new evidence on the modulation of salivary cortisol levels as a result of an ayahuasca session, both in healthy and depressive volunteers. Considering that cortisol acts in regulation of distinct physiological pathways, emotional and cognitive processes, it is assumed to be critically involved to the etiology of depression and its regulation seems to be important for the treatment and remission of major depression, ayahuasca use as antidepressant should be further investigated. Moreover, this study highlights the importance of psychedelics in the treatment of human mental disorders

Physical activity for people with dementia: A scoping study

Background: This scoping study aimed to identify how physical activity may benefit people with dementia; how and/or if current service provide these benefits; and what support they need to do so. Methods: Methods included an evidence review using literature; mapping current service provision through a survey; and in-depth interviews with a sample of service providers. Results: The 26 studies included in the review indicated the potential effectiveness of physical activity for people with dementia, including improvements in cognition and mood, behaviour and physical condition. Mechanisms of action and the link with outcomes were poorly defined and implemented. The mapping survey and related interviews showed that service providers were delivering a range of services broadly consistent with the scientific evidence. They tended to take a holistic view of possible benefits, and focused on enjoyment and well-being, more than specific cognitive, physical and behavioural outcomes highlighted in literature. Service providers needed more evidence based information and resources to develop services and realise their potential. Conclusion: Despite potential benefits demonstrated in literature and practice, there is a need for further research to optimise interventions and to consider some neglected issues including delivery at home and in communities; impacts for carers; physical activities through ADLs; and individual needs. Studies are needed which take a more holistic approach to the effects of physical activity, and outcomes should be broader and include mental health and wellbeing

Diagnóstico socioeconômico ambiental e produtivo da comunidade Cacimba do Baltazar.

Características da Comunidade; Informações Gerais;Trabalho, Ocupação e Renda; Sobre a Educação; Sobre a Saúde e a Alimentação; Diculdades Levantadas pelos Moradores; Associabilidade; Dificuldade de Acesso à Água; Atendimento Médico; Falta de Emprego e de Cursos Profissionalizantes; Inexistência de Classe de Alfabetização de Jovens e Adultos; Dificuldade de Acesso a Transporte; Inexistência de Telefone Público; Dificuldade de Acesso a Benefícios Previdenciários e Assistenciais Grupos de Trabalho; Planos de Atividades.bitstream/CPATSA-2009-09/40204/1/SDC215.pd

Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial

Background Recent open-label trials show that psychedelics, such as ayahuasca, hold promise as fast-onset antidepressants in treatment-resistant depression. Methods To test the antidepressant effects of ayahuasca, we conducted a parallel-arm, double-blind randomized placebo-controlled trial in 29 patients with treatment-resistant depression. Patients received a single dose of either ayahuasca or placebo. We assessed changes in depression severity with the Montgomery-Åsberg Depression Rating Scale (MADRS) and the Hamilton Depression Rating scale at baseline, and at 1 (D1), 2 (D2), and 7 (D7) days after dosing. Results We observed significant antidepressant effects of ayahuasca when compared with placebo at all-time points. MADRS scores were significantly lower in the ayahuasca group compared with placebo at D1 and D2 (p = 0.04), and at D7 (p < 0.0001). Between-group effect sizes increased from D1 to D7 (D1: Cohen's d = 0.84; D2: Cohen's d = 0.84; D7: Cohen's d = 1.49). Response rates were high for both groups at D1 and D2, and significantly higher in the ayahuasca group at D7 (64% v. 27%; p = 0.04). Remission rate showed a trend toward significance at D7 (36% v. 7%, p = 0.054). Conclusions To our knowledge, this is the first controlled trial to test a psychedelic substance in treatment-resistant depression. Overall, this study brings new evidence supporting the safety and therapeutic value of ayahuasca, dosed within an appropriate setting, to help treat depression. This study is registered at http://clinicaltrials.gov (NCT02914769)