Building Resilience on Adolescent Mental Health Associated with Emerging Risk and Protective Factors among Ethnic Groups

A bulk of studies have focused on systematically catalogued risk and protective factors (e.g., parental monitoring, peer, neighborhood support) in terms of adolescent mental health status concerning resilience; however, they did not display any improvement regarding adolescent mental health, particularly in school-based interventions. Therefore, I suggested that whether other emerging factors (e.g., nutrition, physical activity) could be beneficial to promote effective school-based interventions. Hence, I examined adolescent mental health outcomes (depression and suicidality) associated with dietary patterns, physical activity, social support, watching TV, video/computer games, and sleeping habits factors regarding resilience approach. A secondary data analysis was employed based on the 2011 national Youth Risk Behavior Survey (YRBS) among 15,364 12-18 year-old African American, Asian, and Caucasian adolescents. Regarding nutrition, low levels of fruit, vegetable, potato, and fruit juice were associated with higher odds of depression, suicidal ideation, suicide attempts, for the most part among diverse ethnicities. Similarly, greater green salad intake resulted in lower odds of poor mental health outcomes among Asians and Caucasians. Next, consistent with current literature, low levels of social support in schools and higher levels of joining a sport team were strong predictors of poor mental health outcomes among overall ethnic groups. Lastly, healthy sleeping patterns, greater physical activity, low levels of being bullied in school, cyber bullied, and video/computer games increased the risk of poor mental health outcomes among adolescents.published_or_final_versio

A Critical Systematic Review of Studies Regarding Resilience in Turkey: A Call for the Socio-ecology of Resilience Perspective

Even though international research has shifted from problem-driven to strength-based approach such as resilience, very little is known in a non-Western context, Turkey. As a result, this paper aims to fill research gaps in existing peer-reviewed literature by targeting to promote more effective interventions and programs with regard to resilience approach in Turkey. A critical systematic review of available literature was carried out based on peer-reviewed articles published in English and Turkish using PubMed, Ovid, EBSCO HOST, ERIC, ProQuest databases, and hand searching. Four hundred fifty-two articles were retrieved of which 34 met the inclusion criteria. Results depict that the majority of studies solely employed individual-based resilience approach. Even though international resilience research has begun to match resilience to socio-ecological perspective, Turkish scholars hardly do so. Only pointing out this gap in resilience research is addressed, will social workers be help enabling Turkish individuals to fuel resilience

Culturally Relevant Protective and Risk Factors of Youth Risk Behaviors Among Pakistani and Indian Students in Hong Kong: A Focus Group Study

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Additional effect of erenumab for patients with chronic migraine treated with onabotulinumtoxin A—real-world data from a preliminary cohort study

BackgroundThis preliminary retrospective cohort study investigates the potential additive prophylactic effect of erenumab, a fully human monoclonal antibody that blocks the calcitonin gene-related peptide receptor, in combination with ongoing onabotulinumtoxin A (onaBoNT-A) treatment in patients suffering from chronic migraine.MethodsThe study included 218 patients and investigated the effects of adding erenumab to the existing treatment regimen. The primary outcome was the MIDAS (Migraine Disability Assessment) score assessed 3 months after the introduction of erenumab.ResultsThe results indicated a significant improvement of the MIDAS score, suggesting a reduction in migraine-related disability following the addition of erenumab to onaBoNT-A. In the inter group comparison, dual therapy showed a significantly greater reduction of the MIDAS when compared to a switch from onaBoNT-A to erenumab monotherapy, but not compared to initiation of onaBoNT-A monotherapy. It is hypothesized that the observed additive effects are due to the independent modes of action of erenumab and onabotulinumtoxin A.ConclusionThis study suggests that the combination of erenumab with onaBoNT-A may offer an improved approach for the treatment of chronic migraine in selected patients. However, the results highlight the need for prospective, controlled studies to validate these findings and determine the optimal combination of treatments tailored to the individual patient

Current incidence, severity, and management of veno-occlusive disease/sinusoidal obstruction syndrome in adult allogeneic HSCT recipients:an EBMT Transplant Complications Working Party study

The current incidence, diagnostic policy, management, and outcome of VOD/SOS at EBMT centers were studied. All centers that had performed allogeneic HSCTs in adult patients within one defined year were invited to the study. Seventy-one centers participated with a total of 2886 allogeneic transplantations and 93 cases of VOD/SOS in 2018. The cumulative incidence of VOD/SOS at day 21 was 1.8% and at day 100 2.4%. Of 67 cases with detailed data, 52 were classical and 15 (22%) late onset (&gt;day 21). According to the EBMT criteria, 65/67 patients had at least two VOD/SOS risk factors. The severity grades were: mild 0, moderate 3, severe 29, very severe 35. Fifty-four patients were treated with defibrotide. VOD/SOS resolved in 58% of the patients, 3/3 with moderate, 22/28 with severe, and 12/33 with very severe grade (p &lt; 0.001). By day 100, 57% of the patients were alive; 3/3 with moderate, 22/29 with severe, and 13/35 with very severe VOD/SOS (p = 0.002). In conclusion, the incidence of VOD/SOS was low. Severe and very severe grades dominated. Very severe grade predicted poor outcome compared to severe grade further supporting the concept of early diagnosis and treatment to avoid a dismal outcome. [Figure not available: see fulltext.]</p