Solar Reflector Materials Degradation Due to the Sand Deposited on the Backside Protective Paints

Concentrating solar power (CSP) Technologies are foreseen to be a crucial actor in the future renewable energy mix. Soil accumulation on the optical surfaces of CSP plants involves significant expenses of the operation and maintenance activities because a high cleanliness level is required to achieve proper plant revenues. Normally, only the front side of the solar reflectors is cleaned to reflect the maximum possilbe amount of direct solar radiation towards the receiver. However, soil depoisted on the backside of the reflector could provoke degradation and might need to be considered in the cleaning strategyAs this possible degradation has never been studied, this work is dedicated to assess if the backside of refelctros should be regularly cleaned. The influence of the sand in the possible paint degradation depends on its chemical composition and the weather conditions. Therefore, several climatic conditions of artificially soiled reflector samples with different types of sand were simulated in accelerated aging tests. Concerning the results obtained, the ambient conditions simulated by the damp heat and thermal cycling tests were the only ones that produced a significant degradation of the backside paints. Also, the sand from Ouarzazate was responsible for higher Deterioration

Prognostic value of human leukocyte antigen G expression in solid tumors: a systematic review and meta-analysis

IntroductionIdentification of modulators of the immune response with inhibitory properties that could be susceptible for therapeutic intervention is a key goal in cancer research. An example is the human leukocyte antigen G (HLA-G), a nonclassical major histocompatibility complex (MHC) class I molecule, involved in cancer progression. MethodsIn this article we performed a systematic review and meta-analysis on the association between HLA-G expression and outcome in solid tumors. This study was performed in accordance with PRISMA guidelines and registered in PROSPERO.ResultsA total of 25 studies met the inclusion criteria. These studies comprised data from 4871 patients reporting overall survival (OS), and 961 patients, reporting disease free survival (DFS). HLA-G expression was associated with worse OS (HR 2.09, 95% CI = 1.67 to 2.63; P < .001), that was higher in gastric (HR = 3.40; 95% CI = 1.64 to 7.03), pancreatic (HR = 1.72; 95% CI = 0.79 to 3.74) and colorectal (HR = 1.55; 95% CI = 1.16 to 2.07) cancer. No significant differences were observed between the most commonly utilized antibody (4H84) and other methods of detection. HLA-G expression was associated with DFS which approached but did not meet statistical significance. DiscussionIn summary, we describe the first meta-analysis associating HLA-G expression and worse survival in a variety of solid tumors. Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier CRD42022311973

Prospective study of predictors for anxiety, depression, and somatization in a sample of 1807 cancer patients

Abstract In cancer patients, psychological distress, which encompasses anxiety, depression, and somatization, arises from the complex interplay of emotional and behavioral reactions to the diagnosis and treatment, significantly influencing their functionality and quality of life. The aim was to investigate factors associated with psychological distress in cancer patients. This prospective and multicenter study, conducted by the Spanish Society of Medical Oncology (SEOM), included two cohorts of patients with cancer (localized resected or advanced unresectable). They completed surveys assessing psychological distress (BSI-18) before and after cancer treatment and coping (MINI-MAC) and spirituality (FACIT-sp) prior to therapy. A multivariable logistic regression analysis and a Structural Equation Modeling (SEM) were conducted. Between 2019 and 2022, 1807 patients were evaluated, mostly women (54%), average age 64 years. The most frequent cancers were colorectal (30%), breast (25%) and lung (18%). Men had lower levels of anxiety and depression (OR 0.66, 95% CI 0.52–0.84; OR 0.72, 95% CI 0.56–0.93). Colorectal cancer patients experienced less anxiety (OR 0.63, 95% CI 0.43–0.92), depression (OR 0.55, 95% CI 0.37–0.81), and somatization (OR 0.59, 95% CI 0.42–0.83). Patients with localized cancer and spiritual beliefs had reduced psychological distress, whereas those with anxious preoccupation had higher level. SEM revealed a relationship between psychological distress and coping strategies, emphasizing how baseline anxious preoccupation exacerbates post-treatment distress. This study suggests that age, sex, extension and location of cancer, coping and spirituality influence psychological distress in cancer patients