Adherence to self-administered tuberculosis treatment in a high HIV-prevalence setting: a cross-sectional survey in Homa Bay, Kenya.

Good adherence to treatment is crucial to control tuberculosis (TB). Efficiency and feasibility of directly observed therapy (DOT) under routine program conditions have been questioned. As an alternative, Médecins sans Frontières introduced self-administered therapy (SAT) in several TB programs. We aimed to measure adherence to TB treatment among patients receiving TB chemotherapy with fixed dose combination (FDC) under SAT at the Homa Bay district hospital (Kenya). A second objective was to compare the adherence agreement between different assessment tools

Baseline characteristics of the participants.

<p>*10 missing data.</p><p>**ART data missing for 50 HIV positive.</p

Agreement between adherence measurement tools.

<p>Agreement between adherence measurement tools.</p

TB treatment outcome.

*<p>Cured or treatment completed.</p

Posterior probability of adherence (latent class analysis).

<p>+: complete or satisfactory adherence.</p><p>−: unsatisfactory adherence.</p

Adherence (secondary endpoints) of the participants according to the phase of treatment (n = 212).

<p>*Fisher exact.</p><p>**11 missing data.</p

Adherence (main endpoints) of the participants according to the phase of treatment (n = 212).

<p>*Fisher exact.</p><p>**4 missing data.</p><p>***65 missing data or inconsistencies.</p

Survey Profile.

<p>Survey Profile.</p