Complete Polarization Control in Multimode Fibers with Polarization and Mode Coupling

Multimode optical fibers have seen increasing applications in communication, imaging, high-power lasers and amplifiers. However, inherent imperfections and environmental perturbations cause random polarization and mode mixing, making the output polarization states very different from the input one. This poses a serious issue for employing polarization sensitive techniques to control light-matter interactions or nonlinear optical processes at the distal end of a fiber probe. Here we demonstrate a complete control of polarization states for all output channels by only manipulating the spatial wavefront of a laser beam into the fiber. Arbitrary polarization states for individual output channels are generated by wavefront shaping without constraint on input polarizations. The strong coupling between spatial and polarization degrees of freedom in a multimode fiber enables full polarization control with spatial degrees of freedom alone, transforming a multimode fiber to a highly-efficient reconfigurable matrix of waveplates

Evaluación de la variabilidad de la expresión proteica en poblaciones de Perkinsus Olseni, protozoo parásito de moluscos marinos, mediante electroforesis bidimensional y espectrometría de masas

Comunicaciones a congreso

Recent advances in β-thalassemias

β-thalassemias are heterogeneous hereditary anemias characterized by a reduced output of β-globin chains. The disease is most frequent in the temperate regions of the world, where it represents an important health problem. In the last decades, several programs, aimed at controlling the birth rate of thalassemia newborns by screening and prenatal diagnosis of populations with high risk of β-thalassemia, have been successful accomplished. Bone marrow transplantation has offered a definitive cure for the fraction of patients with available donors. In the same time, steady improvements were made in the traditional clinical management of β-thalassemia patients. The introduction of the oral iron chelators deferiprone that preferentially chelates hearth iron and the development of novel NMR diagnostic methods has led to reduced morbility, increased survival and improved quality of life. More recently, major advances have being made in the discovery of critical modifier genes, such as Myb and especially BCL11A (B cell lymphoma 11A), a master regulator of HbF (fetal hemoglobin) and hemoglobin switching. Polimorphysms of BCL11A, Myb and γ-globin genes account for most of the variability in the clinical phenotypes in β-thalassemia and sickle cell anemia patients. Finally, the year 2010 has brought in the first successful experiment of gene therapy in a β-thalassemia patient, opening up the perspective of a generalized cure for all β- thalassemia patients

A psychometric modeling approach to fuzzy rating data

Modeling fuzziness and imprecision in human rating data is a crucial problem in many research areas, including applied statistics, behavioral, social, and health sciences. Because of the interplay between cognitive, affective, and contextual factors, the process of answering survey questions is a complex task, which can barely be captured by standard (crisp) rating responses. Fuzzy rating scales have progressively been adopted to overcome some of the limitations of standard rating scales, including their inability to disentangle decision uncertainty from individual responses. The aim of this article is to provide a novel fuzzy scaling procedure which uses Item Response Theory trees (IRTrees) as a psychometric model for the stage-wise latent response process. In so doing, fuzziness of rating data is modeled using the overall rater's pattern of responses instead of being computed using a single-item based approach. This offers a consistent system for interpreting fuzziness in terms of individual-based decision uncertainty. A simulation study and two empirical applications are adopted to assess the characteristics of the proposed model and provide converging results about its effectiveness in modeling fuzziness and imprecision in rating data

A novel CFA+EFA model to detect aberrant respondents

Aberrant respondents are common but yet extremely detrimental to the quality of social surveys or questionnaires. Recently, factor mixture models have been employed to identify individuals providing deceptive or careless responses. We propose a comprehensive factor mixture model that combines confirmatory and exploratory factor models to represent both the non-aberrant and aberrant components of the responses. The flexibility of the proposed solution allows for the identification of two of the most common aberant response styles, namely faking and careless responding. We validated our approach by means of two simulations and two case studies. The results indicate the effectiveness of the proposed model in handling with aberrant responses in social and behavioral surveys.Comment: 24 pages, 5 figures, 7 table

Bio-inspired functional surface fabricated by electrically assisted micro-embossing of AZ31 magnesium alloy

Developing bio-inspired functional surfaces on engineering metals is of extreme importance, involving different industrial sectors, like automotive or aeronautics. In particular, micro-embossing is one of the efficient and large-scale processes for manufacturing bio-inspired textures on metallic surfaces. However, this process faces some problems, such as filling defects and die breakage due tocsize effect, which restrict this technology for some components. Electrically assisted micro-forming has demonstrated the ability of reducing size effects, improving formability and decreasing flow stress, making it a promising hybrid process to control the filling quality of micro-scale features. This research focuses on the use of different current densities to perform embossed micro-channels of 7 um and sharklet patterns of 10 um in textured bulk metallic glass dies. These dies are prepared by thermoplastic forming based on the compression of photolithographic silicon molds. The results show that large areas of bio-inspired textures could be fabricated on magnesium alloy when current densities higher than 6 A/mm2 (threshold) are used. The optimal surface quality scenario is obtained for a current density of 13 A/mm2. Additionally, filling depth and depth–width ratio nonlinearly increases when higher current densities are used, where the temperature is a key parameter to control, keeping it below the temperature of the glass transition to avoid melting or an early breakage of the die.Peer ReviewedPostprint (published version

Simultaneous spark plasma synthesis and consolidation of WC/Co composites

The single-step synthesis and densification of the WC-6Co cemented carbide starting from elemental powders was obtained by the spark plasma sintering (SPS) technique. The operating conditions that guarantee the complete conversion of the reactants to the desired full dense material have been identified. Specifically, under the application of 800 A and a mechanical pressure of 40 MPa for about 200 s, a product with relative density higher than 99%, hardness of 14.97 ± 0.35 GPa, and 12.5 ± 1.0 MPa m0.5 fracture toughness was obtained. A kinetic investigation of the SPS process was also performed. It revealed that an intermediate phase, i.e., W2C, is the first carbide formed during the carburization process. It was observed that the synthesis and sintering stages take place simultaneously. It was also found that as the applied pulsed current intensity was augmented, the synthesis/sintering time required decreased significantly

La evolución de las finalidades del gasto público argentino en el período 1980-2015: Grados de libertad del gobierno e hipótesis determinista

En este trabajo analizamos la evolución del gasto público argentino en los últimos treinta y cinco años con el objetivo de determinar la capacidad de los gobiernos para reacomodar la asignación de recursos entre las distintas finalidades estatales. En primer lugar, desarrollamos el planteo del problema, haciendo una muy breve reseña de los ciclos históricos de gobernanza, con especial referencia al lugar que se le asignó al Estado en la etapa del ajuste estructural (1980-2001) y del llamado “populismo de izquierda” (2002/2015). En segundo lugar, nos adentramos en el análisis de la evolución de las cuatro finalidades en que se clasifica el gasto: social, económico, funcionamiento del Estado y deuda.\nConcretamente, en la etapa del ajuste estructural nos detenemos a analizar el proceso de reemplazo del gasto en servicios económicos por gasto social y en la etapa populista la reconstrucción de la estructura de intervención estatal en la economía. Para el desarrollo del trabajo tomamos como variable independiente los objetivos de gobierno en cada periodo, mientras que las efectivas variaciones en el gasto por finalidad constituyen la variable dependiente.\nReferimos a un diseño cuasi experimental, en el sentido de que no podemos colegir si los resultados alcanzados tienen que ver con otras variables intervinientes -como, por ejemplo, el contexto nacional o internacional- o a las características propias que hacen a la variable independiente, tales como la forma y condición de la coalición gobernante o la pericia técnica o política de las autoridades en cada caso.Fil: Cao, Horacio Antonio. Universidad de Buenos Aires, Facultad de Ciencias Económicas. Centro de Investigación en Administración Pública