Biostimulants of growth in the production process of grain crops

The role of biostimulants of growth of various natures in the production process of spring wheat variety Zlata was studied, depending on nitrogen nutrition conditions, and was carried out under field conditions.The experiments assessed the activity of the plant assimilation apparatus and the formation of the yield of wheat plants using biostimulants of various natures by spraying vegetative plants. The studies found that the greatest effectiveness of the studied drugs was observed under conditions of optimal provision of nitrogen nutrition to wheat plants. It has been established that the preparations Epin-Extra, Emistim and Hardy increase the efficiency of the assimilation apparatus of spring wheat plants, which led to the receipt of large increases in grain weight under conditions of optimal provision of wheat plants with nitrogen nutrition

Biostimulants of growth in the production process of grain crops

The role of biostimulants of growth of various natures in the production process of spring wheat variety Zlata was studied, depending on nitrogen nutrition conditions, and was carried out under field conditions.The experiments assessed the activity of the plant assimilation apparatus and the formation of the yield of wheat plants using biostimulants of various natures by spraying vegetative plants. The studies found that the greatest effectiveness of the studied drugs was observed under conditions of optimal provision of nitrogen nutrition to wheat plants. It has been established that the preparations Epin-Extra, Emistim and Hardy increase the efficiency of the assimilation apparatus of spring wheat plants, which led to the receipt of large increases in grain weight under conditions of optimal provision of wheat plants with nitrogen nutrition

Discovery of anxiolytic 2-ferrocenyl-1,3-thiazolidin-4-ones exerting GABA(A) receptor interaction via the benzodiazepine-binding site

Herein, we report on the synthesis, spectral, crystallographic and electrochemical properties of a small library of N-substituted 2-ferrocenyl-1,3-thiazolidin-4-ones, designed as novel GABA(A) benzodiazepine-binding site ligands. The anxiolytic properties of the title compounds were evaluated in several different in vivo models, whereas the involvement of the GABAA receptor complex in the activity of the most potent compound, 2-ferrocenyl-3-(4-methoxyphenylethyl)-1,3-thiazolidin-4-one, was inferred from experiments with known GABA(A)-targeting agents. Ligand docking experiments revealed that the high, dose-dependent, anxiolytic activity of the new compounds might be due to their favorable interactions with the benzodiazepine-binding site of the GABA(A) receptor complex. The incorporation of the ferrocene core and fine tuning of the distance between the thiazolidinone core and an additional aromatic ring were judged to be crucial structural requirements for the observed anxiolytic effect. (C) 2014 Elsevier Masson SAS. All rights reserved