1,466 research outputs found

    A mean-removed variation of weighted universal vector quantization for image coding

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    Weighted universal vector quantization uses traditional codeword design techniques to design locally optimal multi-codebook systems. Application of this technique to a sequence of medical images produces a 10.3 dB improvement over standard full search vector quantization followed by entropy coding at the cost of increased complexity. In this proposed variation each codebook in the system is given a mean or 'prediction' value which is subtracted from all supervectors that map to the given codebook. The chosen codebook's codewords are then used to encode the resulting residuals. Application of the mean-removed system to the medical data set achieves up to 0.5 dB improvement at no rate expense

    A meta-analysis of pharmacotherapy for social anxiety disorder: an examination of efficacy, moderators, and mediators

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    INTRODUCTION: Social anxiety disorder (SAD) is among the most prevalent mental disorders, associated with impaired functioning and poor quality of life. Pharmacotherapy is the most widely utilized treatment option. The current study provides an updated meta-analytic review of the efficacy of pharmacotherapy and examines moderators and mediators of treatment efficacy. Areas Covered: A comprehensive search of the current literature yielded 52 randomized, pill placebo-controlled trials of pharmacotherapy for adults diagnosed with SAD. Data on potential mediators of treatment outcome were collected, as well as data necessary to calculate pooled correlation matrices to compute indirect effects. Expert Opinion: The overall effect size of pharmacotherapy for SAD is small to medium (Hedges' g = 0.41). Effect sizes were not moderated by age, sex, length of treatment, initial severity, risk of study bias, or publication year. Furthermore, reductions in symptoms mediated pharmacotherapy's effect on quality of life. Support was found for reverse mediation. Future directions may include sustained efforts to examine treatment mechanisms of pharmacotherapy using rigorous longitudinal methodology to better establish temporal precedence

    Distribution of giardia duodenalis assemblages A and B among children living in a remote Indigenous Community of the Northern Territory, Australia

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    Giardiasis is a communicable gastrointestinal disease caused by Giardia duodenalis and two genetic assemblages, A and B, cause human infection. In remote Indigenous communities of Australia, giardiasis is highly prevalent among children but disease transmission is poorly understood. This study investigated the prevalence of Giardia and genetic subtypes contributing to human disease in a remote Indigenous community, in the Northern Territory of Australia. Eighty-seven faecal samples were collected from 74 children (<15 years) over an 18 month period, and the distribution of positive cases relative to participant age and gender were examined. Screening by microscopy and 18S rRNA PCR amplification showed 66.7% (58/87) of faecal samples were positive for Giardia. Both males and females were equally affected and high detection rates were obtained for participants aged 0–<5 years and 5–<10 years (66.0 and 60.0% respectively). For 58.6% of the positive samples, Giardia was only detected by 18S rRNA PCR. Approximately 75% of cases were assemblage B, and subassemblage analyses using terminal restriction fragment length polymorphism of the glutamate dehydrogenase gene demonstrated that a variety of genetic variants were present. The high proportion of positive cases that were not detectable by microscopy, and dominance of assemblage B cases highlights the need for further research in this community, to assess the contribution of Giardia to chronic gastrointestinal disease among children, and to understand conditions conductive to assemblage B transmission

    Determinants of sedentary behavior, motivation, barriers and strategies to reduce sitting time in older women: a qualitative investigation

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    Abstract: Sedentary behavior defined as time spent non-exercising seated or reclining posture has been identified has a health risk and associated with frailty and disablement for older adults. Older adults are the most sedentary segment of society. To date no study has investigated the determinants of sedentary behavior in older adults. This study reports a qualitative investigation of the determinants of sedentary behavior, strategies and motivator to reduce sitting time by structured interviews in a group of community dwelling older women (N = 11, age 65 and over). Older women expressed the view that their sedentary behavior is mostly determined by pain which acts both as an incentive to sit and a motivator to stand up, lack of energy in the afternoon, pressure from direct social circle to sit and rest, societal and environmental typecasting that older adult are meant to sit, lack of environmental facilities to allow activity pacing. This qualitative investigation highlighted some factors that older adults consider determinants of their sedentary behavior. Some are identical to those affecting physical activity (self-efficacy, functional limitations, ageist stereotyping) but some appear specific to sedentary behavior (locus of control, pain) and should be further investigated and considered during intervention design. Tailore

    Mobile Technologies and Consumer Insights

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    Mobile technology is changing the way consumers consume content and connect with others. At the same time, marketers admit that effectively implementing mobile targeting and promoting deals through mobile devices remains a challenge. To address these challenges and reveal consumer insights in the mobile marketing space, I propose a research stream via three essays that investigate the contextual factors that influence consumer receptivity to mobile messages. One of these factors is environmental contexts, such as the crowdedness of a consumer's environment, which is the focus of the first essay. Another factor is the context of social cues and the framing of the mobile message itself, which is the focus of the second essay. Yet another factor is whether the promoted product has social value beyond the consumption value itself, which is the focus of the third essay. How contextual factors may influence consumer receptivity to targeted mobile promotions is complex and is explored in detail in the following studies.Business Administration/Marketin

    Effect of pectin, lecithin, and antacid feed supplements (Egusin®) on gastric ulcer scores, gastric fluid pH and blood gas values in horses

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    BACKGROUND: The objectives of this study were to evaluate the effects of two commercial feed supplements, Egusin 250(®) [E-250] and Egusin SLH(®) [E-SLH], on gastric ulcer scores, gastric fluid pH, and blood gas values in stall-confined horses undergoing feed-deprivation. METHODS: Nine Thoroughbred horses were used in a three-period crossover study. For the three treatment groups, sweet feed was mixed with E-250, E-SLH, or nothing (control group) and fed twice daily. Horses were treated for 21 days, then an additional 7 days while on an alternating feed-deprivation model to induce or worsen ulcers (period one). In periods two and three, horses (n=6) were treated for an additional 7 days after feed-deprivation. Gastroscopies were performed on day -1 (n=9), day 21 (n=9), day 28 (n=9) and day 35 (n=6). Gastric juice pH was measured and gastric ulcer scores were assigned. Venous blood gas values were also measured. RESULTS: Gastric ulcers in control horses significantly decreased after 21 days, but there was no difference in ulcer scores when compared to the Egusin® treated horses. NG gastric ulcer scores significantly increased in E-250 and control horses on day 28 compared to day 21 as a result of intermittent feed-deprivation, but no treatment effect was observed. NG ulcer scores remained high in the control group but significantly decreased in the E-SLH- and E-250-treated horses by day 35. Gastric juice pH values were low and variable and no treatment effect was observed. Mean blood pCO(2) values were significantly increased two hours after feeding in treated horses compared to controls, whereas mean blood TCO(2) values increased in the 24 hour sample, but did not exceed 38 mmol/l. CONCLUSIONS: The feed-deprivation model increased NG gastric ulcer severity in the horses. However, by day 35, Egusin(®) treated horses had less severe NG gastric ulcers compared to untreated control horses. After 35 days, Egusin(®) products tested here ameliorate the severity of gastric ulcers in stall-confined horses after feed stress

    Differentiation for Gifted and Talented Elementary Students: What Teachers Know and Implement

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    The purpose of this research was to measure the ways elementary school teachers are differentiating instruction for their gifted and talented students and to gauge their awareness of the need for implementing appropriate differentiation strategies they use in their classrooms. The study surveyed elementary teachers currently teaching in one large school district in Kentucky. Teachers responded to 38 survey items, indicating how often they use specific practices with their gifted students versus with their average-achieving students. The results indicated that there is much work to be done to increase teacher awareness of the importance of differentiated instruction for gifted and talented students. Professional learning in gifted education is essential to ensure that these talented students have the opportunity to reach their full potential in their educational lives

    The effects of short-term sea level rise on vegetation communities in coastal Mississippi

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    Salt marshes are important habitats that provide many ecosystem services, but they are susceptible to the impacts of sea level rise (SLR), often resulting in emergent vegetation loss. In areas with enough sediment input, marshes can keep pace with SLR by gaining elevation or through upland migration. However, salt marshes in areas with limited sediment input, such as the Grand Bay National Estuarine Research Reserve, often cannot keep pace with sea level rise. Additionally, the rate of SLR is increasing making it more difficult for marshes to keep pace. To assess the short-term response of marsh vegetation to sea level rise, percent cover, stem density, and elevation, data from 2016 to 2020 in four different marsh elevation zones were analyzed in this study. Results demonstrated that the four marsh elevation zones are responding disparately to SLR. These findings indicate that it is imperative to implement restoration plans to account for site variability to conserve these vital habitats

    The Pyramid Model: Implementation Glows & Grows from Georgia’s Childcare Centers

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    In 2015, the Department of Early Care and Learning (DECAL) and the Metropolitan Regional Educational Service Agency (RESA) launched the state’s first cohort of childcare centers to implement the Pyramid Model. Come hear from some of these early childhood program providers as they share glows and grows experienced during implementation of the various critical elements essential to the Pyramid Model’s framework such as setting and teaching program-wide expectations, family involvement and more. A brief overview of the DECAL’s continued efforts to expand the Pyramid Model across the state will also be shared

    Human Mars Mission Design - The Ultimate Systems Challenge

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    A human mission to Mars will occur at some time in the coming decades. When it does, it will be the end result of a complex network of interconnected design choices, systems analyses, technical optimizations, and non-technical compromises. This mission will extend the technologies, engineering design, and systems analyses to new limits, and may very well be the most complex undertaking in human history. It can be illustrated as a large menu, or as a large decision tree. Whatever the visualization tool, there are numerous design decisions required to assemble a human Mars mission, and many of these interconnect with one another. This paper examines these many decisions and further details a number of choices that are highly interwoven throughout the mission design. The large quantity of variables and their interconnectedness results in a highly complex systems challenge, and the paper illustrates how a change in one variable results in ripples (sometimes unintended) throughout many other facets of the design. The paper concludes with a discussion of some mission design variables that can be addressed first, and those that have already been addressed as a result of ongoing National Aeronautics and Space Administration (NASA) developments, or as a result of decisions outside the technical arena. It advocates the need for a 'reference design' that can be used as a point of comparison, and to illustrate the system-wide impacts as design variables change
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