7,003 research outputs found
Quantum gate for Q switching in monolithic photonic bandgap cavities containing two-level atoms
Photonic bandgap cavities are prime solid-state systems to investigate
light-matter interactions in the strong coupling regime. However, as the cavity
is defined by the geometry of the periodic dielectric pattern, cavity control
in a monolithic structure can be problematic. Thus, either the state coherence
is limited by the read-out channel, or in a high Q cavity, it is nearly
decoupled from the external world, making measurement of the state extremely
challenging. We present here a method for ameliorating these difficulties by
using a coupled cavity arrangement, where one cavity acts as a switch for the
other cavity, tuned by control of the atomic transition.Comment: 6 pages, 5 figures, 1 tabl
Incommensurate Transverse Anisotropy Induced by Disorder and Spin-Orbit-Vibron Coupling in Mn12-acetate
It has been shown within density-functional theory that in Mn-acetate
there are effects due to disorder by solvent molecules and a coupling between
vibrational and electronic degrees of freedom. We calculate the in-plane
principal axes of the second-order anisotropy caused by the second effect and
compare them with those of the fourth-order anisotropy due to the first effect.
We find that the two types of the principal axes are not commensurate with each
other, which results in a complete quenching of the tunnel-splitting
oscillation as a function of an applied transverse field.Comment: Will be presented at MMM conference 200
A Comprehensive Economic Stimulus for our Failing Economy
This paper presents a comprehensive plan to fix the ailing American economy, through a five-step approach. First, the Federal Reserve must continue to broaden the scope of monetary policy, by purchasing and selling long-term securities. Manipulating expectations through FOMC statements is another tool at the Federal Reserve’s disposal. Secondly, the government must enact fiscal stimulus to stabilize the economy in the short and medium runs, through investment in infrastructure projects, green technology, fusion technology, and science education. Additionally, the new fiscal policy must tackle the mortgage meltdown, which is weighing down the entire economy. Third, the regulatory system must be changed to reduce the likelihood of another financial collapse, starting with the nationalization of the ratings agencies. Ratings should be updated faster, with a numeric grading system rather than the pre-existing letter grades. Fourth, our globalized economy insures that a coordinated globalized response is necessary to recover. Global cooperation to reduce inflation and avoid protectionist policies is vital. Finally, the American bailout policy must be made clear, only giving bailouts to companies that are sound but financially strapped and those that are too big to fail
Effects of eddy vorticity forcing on the mean state of the Kuroshio Extension
Author Posting. © American Meteorological Society, 2015. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Journal of Physical Oceanography 45 (2015): 1356–1375, doi:10.1175/JPO-D-13-0259.1.Eddy–mean flow interactions along the Kuroshio Extension (KE) jet are investigated using a vorticity budget of a high-resolution ocean model simulation, averaged over a 13-yr period. The simulation explicitly resolves mesoscale eddies in the KE and is forced with air–sea fluxes representing the years 1995–2007. A mean-eddy decomposition in a jet-following coordinate system removes the variability of the jet path from the eddy components of velocity; thus, eddy kinetic energy in the jet reference frame is substantially lower than in geographic coordinates and exhibits a cross-jet asymmetry that is consistent with the baroclinic instability criterion of the long-term mean field. The vorticity budget is computed in both geographic (i.e., Eulerian) and jet reference frames; the jet frame budget reveals several patterns of eddy forcing that are largely attributed to varicose modes of variability. Eddies tend to diffuse the relative vorticity minima/maxima that flank the jet, removing momentum from the fast-moving jet core and reinforcing the quasi-permanent meridional meanders in the mean jet. A pattern associated with the vertical stretching of relative vorticity in eddies indicates a deceleration (acceleration) of the jet coincident with northward (southward) quasi-permanent meanders. Eddy relative vorticity advection outside of the eastward jet core is balanced mostly by vertical stretching of the mean flow, which through baroclinic adjustment helps to drive the flanking recirculation gyres. The jet frame vorticity budget presents a well-defined picture of eddy activity, illustrating along-jet variations in eddy–mean flow interaction that may have implications for the jet’s dynamics and cross-frontal tracer fluxes.A. S. Delman (ASD) and J. L. McClean (JLM) were supported by NSF Grant OCE-0850463 and Office of Science (BER), U.S. Department of Energy, Grant DE-FG02-05ER64119. ASD and J. Sprintall were also supported by a NASA Earth and Space Science Fellowship (NESSF), Grant NNX13AM93H. JLM was also supported by U.S. DOE Office of Science grant entitled “Ultra-High Resolution Global Climate Simulation” via a Los Alamos National Laboratory subcontract. S. R. Jayne was supported by NSF Grant OCE-0849808. Computational resources for the model run were provided by NSF Resource Grants TG-OCE110013 and TG-OCE130010.2015-11-0
Acute Effects of Vibrating Insoles on Dynamic Balance and Gait Quality in Individuals With Diabetic Peripheral Neuropathy: A Randomized Crossover Study
OBJECTIVE This study investigated the effects of vibrating insoles on dynamic balance and gait quality during level and stair walking and explored the influence of vibration type and frequency in individuals with diabetic peripheral neuropathy (DPN). RESEARCH DESIGN AND METHODS Twenty-two men with DPN were assessed for gait quality and postural and dynamic balance during walking and stair negotiation using a motion capture system and force plates across seven vibratory insole conditions (Vcs) versus a control (Ctrl) condition (insole without vibration). Vibration was applied during standing and walking tasks, and 15-min rest-stop periods without vibration were interposed between conditions. Repeated measures test conditions were randomized. The primary outcomes were gait speed and dynamic balance. RESULTS Gait speed during walking significantly improved in all Vcs compared with Ctrl (P < 0.005), with Vc2, Vc4, and Vc6 identified as the most effective. Gait speed increased (reflecting faster walking) during stair ascent and descent in Vc2 (Ctrl vs. Vc2 for ascent 0.447 ± 0.180 vs. 0.517 ± 0.127 m/s; P = 0.037 and descent 0.394 ± 0.170 vs. 0.487 ± 0.125 m/s; P = 0.016), Vc4 (Ctrl vs. Vc4 for ascent 0.447 ± 0.180 vs. 0.482 ± 0.197 m/s; P = 0.047 and descent 0.394 ± 0.170 vs. 0.438 ± 0.181 m/s; P = 0.017), and Vc6 (Ctrl vs. Vc6 for ascent 0.447 ± 0.180 vs. 0.506 ± 0.179 m/s; P = 0.043 and descent 0.394 ± 0.170 vs. 0.463 ± 0.159 m/s; P = 0.026). Postural balance improved during quiet standing with eyes closed in Vc2, Vc4, Vc6, and Vc7 (P < 0.005). CONCLUSIONS Vibrating insoles are an effective acute strategy for improving postural balance and gait quality during level walking and stair descent in individuals with DPN. These benefits are particularly evident when the entire plantar foot surface is stimulated
uPAR Induces Expression of Transforming Growth Factor β and Interleukin-4 in Cancer Cells to Promote Tumor-Permissive Conditioning of Macrophages
Cancer cells condition macrophages and other inflammatory cells in the tumor microenvironment so that these cells are more permissive for cancer growth and metastasis. Conditioning of inflammatory cells reflects, at least in part, soluble mediators (such as transforming growth factor β and IL-4) that are released by cancer cells and alter the phenotype of cells of the innate immune system. Signaling pathways in cancer cells that potentiate this activity are incompletely understood. The urokinase receptor (uPAR) is a cell-signaling receptor known to promote cancer cell survival, proliferation, metastasis, and cancer stem cell–like properties. The present findings show that uPAR expression in diverse cancer cells, including breast cancer, pancreatic cancer, and glioblastoma cells, promotes the ability of these cells to condition co-cultured bone marrow–derived macrophages so that the macrophages express significantly increased levels of arginase 1, a biomarker of the alternatively activated M2 macrophage phenotype. Expression of transforming growth factor β was substantially increased in uPAR-expressing cancer cells via a mechanism that requires uPA-initiated cell signaling. uPAR also controlled expression of IL-4 in cancer cells via a mechanism that involves activation of ERK1/2. The ability of uPAR to induce expression of factors that condition macrophages in the tumor microenvironment may constitute an important mechanism by which uPAR promotes cancer progression
Polyploidy Did Not Predate the Evolution of Nodulation in All Legumes
BACKGROUND: Several lines of evidence indicate that polyploidy occurred by around 54 million years ago, early in the history of legume evolution, but it has not been known whether this event was confined to the papilionoid subfamily (Papilionoideae; e.g. beans, medics, lupins) or occurred earlier. Determining the timing of the polyploidy event is important for understanding whether polyploidy might have contributed to rapid diversification and radiation of the legumes near the origin of the family; and whether polyploidy might have provided genetic material that enabled the evolution of a novel organ, the nitrogen-fixing nodule. Although symbioses with nitrogen-fixing partners have evolved in several lineages in the rosid I clade, nodules are widespread only in legume taxa, being nearly universal in the papilionoids and in the mimosoid subfamily (e.g., mimosas, acacias)--which diverged from the papilionoid legumes around 58 million years ago, soon after the origin of the legumes. METHODOLOGY/PRINCIPAL FINDINGS: Using transcriptome sequence data from Chamaecrista fasciculata, a nodulating member of the mimosoid clade, we tested whether this species underwent polyploidy within the timeframe of legume diversification. Analysis of gene family branching orders and synonymous-site divergence data from C. fasciculata, Glycine max (soybean), Medicago truncatula, and Vitis vinifera (grape; an outgroup to the rosid taxa) establish that the polyploidy event known from soybean and Medicago occurred after the separation of the mimosoid and papilionoid clades, and at or shortly before the Papilionoideae radiation. CONCLUSIONS: The ancestral legume genome was not fundamentally polyploid. Moreover, because there has not been an independent instance of polyploidy in the Chamaecrista lineage there is no necessary connection between polyploidy and nodulation in legumes. Chamaecrista may serve as a useful model in the legumes that lacks a paleopolyploid history, at least relative to the widely studied papilionoid models
Discovery of a Gas-Rich Companion to the Extremely Metal-Poor Galaxy DDO 68
We present HI spectral-line imaging of the extremely metal-poor galaxy DDO
68. This system has a nebular oxygen abundance of only 3% Z, making
it one of the most metal-deficient galaxies known in the local volume.
Surprisingly, DDO 68 is a relatively massive and luminous galaxy for its metal
content, making it a significant outlier in the mass-metallicity and
luminosity-metallicity relationships. The origin of such a low oxygen abundance
in DDO 68 presents a challenge for models of the chemical evolution of
galaxies. One possible solution to this problem is the infall of pristine
neutral gas, potentially initiated during a gravitational interaction. Using
archival HI spectral-line imaging obtained with the Karl G. Jansky Very Large
Array, we have discovered a previously unknown companion of DDO 68. This
low-mass (M 2.810 M), recently
star-forming (SFR 1.410 M yr,
SFR 710 M yr) companion has
the same systemic velocity as DDO 68 (V 506 km s; D
12.740.27 Mpc) and is located at a projected distance of 42 kpc. New HI
maps obtained with the 100m Robert C. Byrd Green Bank Telescope provide
evidence that DDO 68 and this companion are gravitationally interacting at the
present time. Low surface brightness HI gas forms a bridge between these
objects.Comment: Accepted for publication in the Astrophysical Journal Letter
The role of discharge variability in determining alluvial stratigraphy
We illustrate the potential for using physics-based modeling to link alluvial stratigraphy to large river morphology and dynamics. Model simulations, validated using ground penetrating radar data from the Río Paraná, Argentina, demonstrate a strong relationship between bar-scale set thickness and channel depth, which applies across a wide range of river patterns and bar types. We show that hydrologic regime, indexed by discharge variability and flood duration, exerts a first-order influence on morphodynamics and hence bar set thickness, and that planform morphology alone may be a misleading variable for interpreting deposits. Indeed, our results illustrate that rivers evolving under contrasting hydrologic regimes may have very similar morphology, yet be characterized by marked differences in stratigraphy. This realization represents an important limitation on the application of established theory that links river topography to alluvial deposits, and highlights the need to obtain field evidence of discharge variability when developing paleoenvironmental reconstructions. Model simulations demonstrate the potential for deriving such evidence using metrics of paleocurrent variance
Accretion onto the Supermassive Black Hole in M87
Chandra X-ray observations of the giant elliptical galaxy M87 resolve the
thermal state of the hot interstellar medium into the accretion (Bondi) radius
of its central 3 10^9 Msun black hole. We measure the X-ray gas temperature and
density profiles and calculate the Bondi accretion rate, Mdot_Bondi \sim 0.1
Msun/yr. The X-ray luminosity of the active nucleus of M87 observed with
Chandra is L_{x, 0.5-7 \keV} \sim 7 \times 10^{40}erg/s. This value is much
less than the predicted nuclear luminosity, L_{Bondi} \sim 5 \times 10^{44}
erg/s, for accretion at the Bondi rate with a canonical accretion radiative
efficiency of 10%. If the black hole in M87 accretes at this rate it must do so
at a much lower radiative efficiency than the canonical value. The
multiwavelength spectrum of the nucleus is consistent with that predicted by an
advection-dominated flow. However, as is likely, the X-ray nucleus is dominated
by jet emission then the properties of flow must be modified, possibly by
outflows. We show that the overall energetics of the system are just consistent
with the predicted Bondi nuclear power. This suggests that either most of the
accretion energy is released in the relativistic jet or that the central engine
of M87 undergoes on-off activity cycles. We show that, at present, the energy
dumped into the ISM by the jet may reduce the accretion rate onto the black
hole by a factor \propto (v_j/c_s)^{-2}, where v_j is the jet velocity and c_s
the ISM sound speed, and that this is sufficient to account for the low nuclear
luminosity.Comment: emulateapj.sty, revised version, accepted by Ap
- …