Abordagem clínica da leucoplasia verrucosa proliferativa

O cancro oral é um dos 10 cancros mais comuns no mundo, apresentando taxas de mortalidade elevadas. É na maioria das vezes diagnosticado tardiamente. Contudo sabe-se que existe um grupo de lesões, designadas, de potencialmente malignas, que têm capacidade de evoluir e progredir até cancro oral. Entre este encontra-se a leucoplasia oral, caracterizada como uma mancha ou placa branca que não pode ser identificada clínica ou patologicamente como nenhuma outra lesão branca e sem etiologia conhecida para além do tabaco (OMS, 1978). Existem vários tipos de leucoplasias, contudo há uma rara, sem etiologia conhecida e com caracter bastante agressivo, designada, leucoplasia verrucosa proliferativa. É caracterizada como uma leucoplasia de progressão lenta, com características multifocais, que se apresenta clinicamente com aspeto verrucoso e com prolongamentos exofíticos e proliferativos. Apresenta elevadas taxas de transformação maligna e de recidiva após tratamento, não havendo ainda um tratamento totalmente eficaz. Devido a sua elevada taxa de transformação maligna e a evolução para carcinoma verrucoso e carcinoma de células escamosas, é importante que seja feito um diagnóstico precoce, para que se tente travar a sua evolução, o que melhora o prognóstico e a morbilidade associada à lesão. Diminuindo, assim, também, a incidência de cancro oral, ou pelo menos a incidência de cancro oral extensivo.Oral Cancer is one of the 10 most common cancers in the world, with high mortality rates. Is most often diagnosed late. However, it is known that there is a group of potentially malignant lesions that have the ability to evolve into oral cancer. Spot or white plaque that can not be identified clinically or pathologically as no other white lesion and no known etiology other than tobacco (WHO, 1978). There are several types of leukoplakias, however there is a leukoplakia without kown etiology, rare and with a very aggressive character, called proliferative verrucous leukoplakia. Is characterized as a slow progression leukoplakia, with multifocal features, that presents clinically verrucous appearance and with exophytic and proliferative projections. Presents with high rates of malignant transformation and relapse after treatment, with no totally effective treatment. Because of its high rate of malignant transformation and evolution in to verrucous carcinoma and squamous cell carcinoma, it is important that exists early diagnosis to try to halt its evolution and reducing the incidence of oral cancer or extensive oral cancer

Personalidade da marca : uma aplicação à marca Açores

Dissertação de Mestrado, Ciências Económicas e Empresariais, 2 de Fevereiro de 2016, Universidade dos Açores.Num mundo cada vez mais globalizado e com cada vez maior facilidade de acesso a informação por parte dos consumidores, estes tornam-se de dia para dia mais exigentes e menos fiéis na sua escolha de marcas. Assim, torna-se crucial as empresas e marcas focarem-se na sua diferenciação das restantes e colocarem o consumidor no centro de todo o processo. Tal como na escolha de um produto ou serviço, a escolha de um local para onde viajar também é muito influenciada pela imagem que o consumidor tem de cada destino turístico. Deste modo, estes também necessitam de estratégias que potenciem a sua atratividade criando vantagens e características a eles indissociáveis, favorecendo a criação de uma imagem clara do destino. Neste contexto, o presente estudo tem como principal objetivo determinar e identificar as principais determinantes da perceção da personalidade do destino turístico Açores.ABSTRACT: In a world increasingly globalized and with an easier access to information, consumers become more demanding and less loyal about choosing brands. Thus, it’s crucial the companies and brands focus in their differentiation from others and put the consumer in the center of all process. Just like in a choice for a product or service, the choice of a place to travel is also influenced by the image that the consumer has for each destination. Therefore, places also need strategies that boost their attractiveness, that highlight their particular and unique characteristics, which create a clear image about the place. In this context, the following study has the purpose to define the main elements for the perception of the personality of the Azores

O conflito na educação de infância: conceções e práticas dos educadores

O presente relatório, no âmbito do Mestrado em Educação Pré-Escolar realizado na Escola Superior de Educação do Instituto Politécnico de Santarém, está dividido em três partes. A primeira parte é dedicada aos estágios em três contextos, dois de creche e um de jardim-de-infância e refere-se aos trabalhos e projetos desenvolvidos ao longo do percurso académico. A segunda parte refere-se à componente investigativa “O conflito na educação de infância: Conceções e práticas dos educadores.” O principal objetivo deste estudo centra-se em compreender qual o papel do/a educador/a na gestão de conflitos entre as criança em contexto educativo. Pretende-se ao longo deste estudo perceber qual o modo como as educadoras de infância conceptualizam o conflito e identificar e descrever as estratégias que utilizam na resolução/mediação dos conflitos. O estudo realizado é de natureza qualitativa, recolhendo informação documental a partir da bibliografia consultada e através de entrevistas semiestruturadas realizadas a quatro educadoras, consequentemente os dados recolhidos foram sujeitos a análise. A terceira e última parte, considerações finais, sintetiza o percurso realizado e o seu contributo para o desenvolvimento e crescimento pessoal e profissional da autora, como futura educadora de infância. Concluindo este estudo permitiu conhecer diversas estratégias a utilizar na resolução dos conflitos mas mais importante, independentemente da estratégia, é respeitar e mostrar reconhecimento sobre aquilo que a criança esta a sentir e levar as crianças a serem participantes no processo de resolução de conflitos. A solução deve sempre ser justa e razoável.This report, in the scope of Master’s Degree in Pre-School Education held at School of Education of the Polytechnic Institute of Santarém, is divided into three parts. The first part is dedicated to the placements performed in three contexts, two of them in nursery and one of kindergarten and refers to the works and projects developed along the academic career. The second part refers to the research component "The Conflict in Childhood Education: Conceptions and Practices of Educators". The main objective of this study is to understand the role of the educator in the management of Between children in an educational context. It is intended throughout this study to understand how the educators of childhood conceptualize the conflict and to identify and to describe the strategies that they use in the resolution / mediation of the conflicts. The study was qualitative in nature, collecting documentary information from the bibliography consulted and through semi-structured interviews conducted to four educators, consequently the data collected were subject to analysis. The third and last part, final considerations, summarizes the course and contribution to the development and personal and professional growth of the author as a future kindergarten teacher. Concluding this study allowed to know several strategies to be used in conflict resolution but more important, regardless of strategy, is to respect and show recognition of what the child is feeling and lead children to be participants in the conflict resolution process. The solution must always be fair and reasonable.N/

Citizen participation in city planning and public decision assisted with ontologies and 3D semantics

Sustainable development of cities implies investigating cities in a holistic way taking into account many interrelations between various urban and environmental problems. Urban models are created with the objective of helping city planners and stakeholders in their decision-making processes. Models which represent in 3 dimensions the geometric elements of a city are called 3D city models. These models are increasingly used in different cities and countries for an intended wide range of applications beyond mere visualization. Such uses are made possible by adding semantics to the geometrical aspects, leading to semantically enriched 3D city models. This can be achieved by using the primary data and ontologies to achieve the semantic enrichment of 3D city models as well as their interoperability with other urban models. Objective of the paper is to present how semantically enriched 3D city models and ontologies may help in sustainable landscape city planning

Interventions infirmières visant la gestion des troubles du sommeil dans le contexte de l'oncologie

L’évaluation des troubles du sommeil dans la population oncologique est centrale. La thérapie cognitive comportementale est l’intervention de choix et plusieurs de ces composantes peuvent être prodiguées par le personnel infirmier. D’autres recherches sont nécessaires pour développer de nouvelles interventions infirmières liées aux troubles du sommeil

Formação em saúde : práticas e perspectivas no campo da saúde coletiva

Organizadores Francis Sodré, Maria Angélica Carvalho Andrade, Rita de Cássia Duarte Lima, Ana Cláudia Pinheiro Garcia

Clinical performance of an infliximab rapid quantification assay

Background: Therapeutic drug monitoring (TDM)-based algorithms can be used to guide infliximab (IFX) adjustments in inflammatory bowel disease (IBD) patients. This study aimed to explore a rapid IFX-quantification test from a clinical perspective. Methods: This manuscript describes a prospective cohort study involving 110 ulcerative colitis (UC) patients on the maintenance phase of IFX. IFX trough levels were quantified using a rapid quantification assay and a commonly-used reference kit. Results: Irrespective of the assay used to measure IFX, its through levels were statistically different between patients with and without endoscopic remission (Mayo endoscopic score = 0), as well as between patients stratified by their faecal calprotectin (FC) levels. Despite the fact that the two methods correlated well with each other [Spearman's rank correlation coefficient = 0.843, p < 0.001; intraclass correlation coefficients = 0.857, 95% confidence interval (CI): 0.791-0.903], there was a discernible systematic variation; values obtained with the reference kit were on average 2.62 units higher than those obtained with the rapid assay. Notwithstanding, 3 mu g/ml was shown to be an acceptable cut-off to assess endoscopic status and inflammatory burden levels using both assays. The percentage of patients that had a positive outcome when the IFX concentration measured by the rapid assay ranked above 3 mu g/ml was 88% both for a Mayo endoscopic score <= 1 and for an FC concentration <250 mu g/g. Conclusions: Based on this study, we concluded that using the rapid IFX assessment system with a 3 mu g/ml threshold is a reliable alternative to the time-consuming enzyme-linked immunosorbent assays in patients on the maintenance phase of IFX.Portuguese IBD Group (GEDII, Grupo de Estudo da Doenca Inflamatoria Intestinal)info:eu-repo/semantics/publishedVersio

Hybrid coatings enriched with tetraethoxysilane for corrosion mitigation of hot-dip galvanized steel in chloride contaminated simulated concrete pore solutions

Hybrid sol-gel coatings, named U(X):TEOS, based on ureasilicate matrices (U(X)) enriched with tetraethoxysilane (TEOS), were synthesized. The influence of TEOS addition was studied on both the structure of the hybrid sol-gel films as well as on the electrochemical properties. The effect of TEOS on the structure of the hybrid sol-gel films was investigated by solid state Nuclear Magnetic Resonance. The dielectric properties of the different materials were investigated by electrochemical impedance spectroscopy. The corrosion behavior of the hybrid coatings on HDGS was studied in chloride-contaminated simulated concrete pore solutions (SCPS) by polarization resistance measurements. The roughness of the HDGS coated with hybrids was also characterized by atomic force microscopy. The structural characterization of the hybrid materials proved the effective reaction between Jeffamine® and 3-isocyanate propyltriethoxysilane (ICPTES) and indicated that the addition of TEOS does not seem to affect the organic structure or to increase the degree of condensation of the hybrid materials. Despite the apparent lack of influence on the hybrids architecture, the polarization resistance measurements confirmed that TEOS addition improves the corrosion resistance of the hybrid coatings (U(X):TEOS) in chloride-contaminated SCPS when compared to samples prepared without any TEOS (U(X)). This behavior could be related to the decrease in roughness of the hybrid coatings (due TEOS addition) and to the different metal coating interaction resulting from the increase of the inorganic component in the hybrid matrix.COST Action MP1202 (HINT) “Rational design of hybrid organic/inorganic interfaces: the next step towards advanced functional materials”The authors would like to gratefully acknowledge the financial support from Fundação para a Ciência e Tecnologia (FCT) for the PhD grant SFRH/BD/62601/2009 and to Hugo Gomes for assisting in the execution of Figures 2 and 3. The research was performed within the frame of COST Action MP1202 (HINT) “Rational design of hybrid organic/inorganic interfaces: the next step towards advanced functional materials”. The COST action MP1202 (HINT) is acknowledged for providing funding for COST-STSM-MP1202-32076 grant that contributed to this research project.info:eu-repo/semantics/publishedVersio

Infidelity in Dating Relationships: Gender-Specific Correlates of Face-to-Face and Online Extradyadic Involvement

This study examined the gender-specific correlates of face-to-face and online extradyadic involvement (EDI) in dating relationships. The sample consisted of 561 women (M age = 23.19 years) and 222 men (M age = 23.97 years), all of whom reported being in an exclusive dating relationship for an average of 35 months. Participants completed the following self-report measures: Extradyadic Behavior Inventory, Attitudes toward Infidelity Scale, and Investment Model Scale. During the current relationship, men were more likely than women to report engagement in face-to-face physical/sexual EDI (23.4 vs. 15.5 %) and online sexual EDI (15.3 vs. 4.6 %). Both men and women with a history of infidelity in a prior relationship were more likely to engage in EDI. More positive attitudes toward infidelity, lower relationship satisfaction, lower commitment, and higher quality of alternatives were significantly associated with EDI, regardless of gender. Women reporting infidelity of a partner in a prior relationship were more likely to engage in face-to-face and online emotional EDI; a longer relationship and a younger age at the first sexual encounter were significant correlates of the engagement in face-to-face emotional EDI. Women with higher education were approximately three times more likely to engage in online sexual EDI. Although men and women are converging in terms of overall EDI, men still report higher engagement in physical/sexual extradyadic behaviors, and the correlates of sexual and emotional EDI vary according to gender. This study contributes to a comprehensive approach of factors influencing the likelihood of EDI and encourages future research in this area