Cardio metabolic risk factors for atrial fibrillation in type 2 diabetes mellitus: Focus on hypertension, metabolic syndrome and obesity

Objective. Atrial fibrillation (AF) in type 2 diabetes mellitus (T2DM) has been little explored so far. However, there are several cardio metabolic risk factors for AF in T2DM patients, such as arterial hypertension, obesity or the metabolic syndrome. Our objective was to evaluate cardio metabolic risk factors for AF in T2DM patients. Methods. We studied the medical records of T2DM patients hospitalized in the Internal Medicine department of an emergency referral hospital in Bucharest, Romania. The study was observational, retrospective and carried out between January-June 2018. Results. The study group included 221 T2DM patients (with a mean age of 68.65 ± 10.64, ranging between 37-93 years): 116 women (52.49%; with a mean age of 70.53 ± 10.69, ranging between 37-93 years) and 105 men (47.51%; with a mean age of 66.57 ± 10.23, ranging between 38-91 years). 92 patients had AF (41.63%): 40 women (34.48%) and 52 men (49.52%). 180 patients (81.45%) were hypertensive: 103 women (88.79%) and 77 men (73.33%). 113 patients (51.13%) had metabolic syndrome: 58 women (50.00%) and 55 men (52.38%). 77 patients (34.84%) were obese: 45 women (38.79%) and 32 men (30.48%). AF patients associated obesity in 26 cases (28.26%), hypertension in 73 cases (79.35%) and metabolic syndrome in 56 cases (60.87%). Conclusions. Out of the study group, 92 T2DM patients (41.63%) had AF, men being more likely to suffer from AF than women (p=0.0288). Hypertension affected 180 patients (81.45%) and in greater proportion women vs. men (p=0.0051). The metabolic syndrome and obesity were discovered in 113 patients (51.13%) and 77 patients (34.84%), respectively, with no significant differences in terms of gender. In our research, the highest cardio metabolic risk factors for AF in T2DM were hypertension (OR = 3.6675) and the metabolic syndrome (OR = 3.3388)

The Economic and Social Effects of Unemployment in Romania

Unemployment is considered as a negative element of economic development that affects in varying proportions all countries, especially those underdeveloped and those in transitions to the market economy. This paper presents the "Economic and Social Effects of Unemployment in Romania", where we presented the unemployment in the contemporary world, its typology and its measurement, namely: the evolution of the number of unemployed, a rate of unemployment and its structure in Romania. Unemployment has become a problem, along with industrial development, since the second half of the 18th century, in times of recession, when industrial enterprises shrank their production and therefore released a large number of workers who became unemployed. In Romania, unemployment is partly due to the transformation of the structure of a national economy, according to the criterion of efficiency, in order to adapt to the competitive environment

The Parents Perception of Martial Arts Practiced by their Children

Parents will always want the best for their offspring. Nowadays, safety and security are something that everyone seeks. From the point of view of Maslow pyramid of needs, safety is on the second level after satisfying the physiological needs. In this article, we conducted two researches: on one hand, a qualitative study to discover the motives why parents urge their kids to train in different martial arts styles, and the latter, a quantitative research, to reveal which type of martial arts is better perceived on different social media platforms networks. The martial arts styles that we analyzed are: Aikido, Kyokushin and Shotokan. We have chosen these three styles as they are some of the best known and practice martial arts, especially want by children. Parents want their kids to develop in harmony, to consume their energy during practice as to get more focused at school and resolve their chores, be disciplined, stronger and more importantly be independent. Not being member of a team sport, the kid will rely only on his own power and capacity to deal with in different situations and not only. Studying and practicing karate, can also be a good protection for those who are bullied as a way of combating this kind of phenomenon that can have tremendous repercussions and even furthermore, to prepare them for the future. The recent incidents that happened both in the country and abroad, both inside and outside schools, can only reinforce the need to practice some defense sports

Challenges Regarding the Performance of Public Investment Projects

Investments, approached as a factor influencing the future, have an essential role in economic growth and development by stimulating the production process and by creating new, high-performing structures that are correlated with the specific needs of individuals and society. From the point of view of access to resources, but also of economic-social competition, economic development generates a higher level of performance, certified on the basis of qualitative and quantitative evaluation processes. In this context, the analysis system of investment projects must be based on operational principles and instruments with medium and long-term impact, capable of aligning with strategic visions. In this paper, based on the research carried out in the specialized literature and the analyzed studies regarding public investments, we identify the current challenges regarding the performance of public investment projects and propose a series of criteria for evaluating the performance of public investments and a sequence of stages to ensure the elimination of non-performing projects at the local, regional and national level. The results of the present research reveal the inadequate prioritization of public investments to ensure adequate sustainability and offer us the opportunity to develop new research directions in the following works in which we will analyze the impact that inadequate prioritization has on the sustainability of local, regional and national communities

The evaluation of oxidative stress in patients with essential thrombocythemia treated with risk-adapted therapy

Introduction. Essential thrombocythemia (ET) is a clonal disorder of the hematopoietic stem cells characterized by persistent thrombocytosis in the peripheral blood, excessive proliferation of megakaryocytes and minor reticulin fibrosis in the bone marrow. It seems that oxidative stress is involved in the development and progression of ET. Objective. To evaluate oxidative stress levels in ET patients treated with risk-adapted therapy. Material and methods. 62 ET patients and 20 controls (informed consent obtained) were enrolled. ET diagnosis was based on WHO criteria (2016 revised). Reactive oxygen species (ROS) levels and the total antioxidant capacity (TAC) were evaluated at time of diagnosis and after 6 months of risk-adapted therapy. ET patients were divided into 3 groups and treated with risk–adapted therapy: a low risk group, treated with low doses of aspirin 75 mg/day or watch-and-wait; an intermediate risk group treated with low doses of aspirin 100 mg/day or low-dose aspirin + cytoreductive treatment; a high-risk group, treated with low doses of aspirin and cytoreductive treatment (hydroxyurea) or platelet-lowering agents (anagrelide). Results. ET patients had at diagnosis higher ROS levels and a lower TAC vs. controls. After 6 months of risk-adapted therapy, ROS levels decreased and TAC increased. No significant differences were seen between the effect of hydroxyurea and the effect of anagrelide on oxidative stress levels. Conclusions. ROS levels are increased and TAC is decreased in ET patients vs. controls. These values depend on the risk group assigned to the patient. Risk-adapted therapy was useful to reduce ROS levels and increase TAC

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements