868 research outputs found

    Between deserts and jungles : the emergence and circulation of sylvatic plague (1920-1950)

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    Research leading to this article was funded by the Wellcome Trust [grant ID 217988/Z/19/Z] for the project “The Global War Against the Rat and the Epistemic Emergence of Zoonosis.”I trace the development of the concept of sylvatic plague – the first sylvatic disease – examining its invention by Ricardo Jorge to describe a global phenomenon of plague reservoirs among wild rodents, and its circulation. The concept implied a space where plague was enzootic, and relied on a division between inhabited and uninhabited spaces and between domestic rats and wild rodents. Some of the characteristics of this space varied, but it always referred to places imagined as empty of humans and rats. In 1927, it designated ambiguously deserts, in 1935, uninhabited regions in general, and in Brazil, it referred to the jungle. O artigo retraça o desenvolvimento do conceito de peste selvática, a primeira doença selvática, da utilização por Ricardo Jorge para descrever um fenômeno global de reservatórios de peste entre roedores selvagens, até sua circulação nos anos 1930 e 40. O conceito inventou um espaço onde a peste se mantinha enzoótica, dividindo entre lugares habitados e inabitados, e roedores domésticos e selvagens. Algumas características desse espaço mudaram com o tempo, mas sempre mantendo a ideia de lugares imaginados como vazios de humanos e ratos. Em 1927, o conceito designava ambiguamente desertos, em 1935, regiōes desabitadas em geral, e no Brasil, ele se referia à selva.Publisher PDFPeer reviewe

    Emerging infectious diseases and disease emergence : critical, ontological and epistemological approaches

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    Funding: Research leading to this article was funded by the Wellcome Trust [grant ID 217988/Z/19/Z] for the project “The Global War Against the Rat and the Epistemic Emergence of Zoonosis.” For the purpose of open access, the author has applied a CC BY public copyright license to any Author Accepted Manuscript version arising from this submission.This paper provides an introduction to the history of the concept of “emerging infectious diseases” (EID) and reflects on how humanities and social science scholars have interacted with it. It starts with a chronological outline of the coinage of the concept in the early 1990s in the wake of the shocks provoked by Ebola and HIV/AIDS, which disrupted the idea that the West was transitioning from a period of infectious diseases to one of chronic diseases. We argue that humanities and social science scholars in disciplines such as history, anthropology, STS, and literature studies have critically explored the concept, showing how entrenched it was in the perceptions of the US and Europe about threats posed by the rest of the globe. Moreover, we explore how scholars in the humanities have used the EID concept to comment on contemporary realities and mobilized it to create dialogues with scientists, especially during the COVID-19 pandemic. Subsequently, we explore how the growing contemporary interest in EID has pushed historians to research the ontological and epistemological factors that enabled the “emergence” of diseases long before the invention of the EID concept, such as plague, Chagas disease, and sleeping sickness, as well as the factors that transformed these and other emerging diseases into pandemics. We conclude by outlining a few neglected factors in the EID literature that could be addressed: the circulation and reception of the concept outside of the West, the examination of EID as a problem for wild animals and not just for humans, and global histories of disease emergence as an epistemological and social process.PostprintPeer reviewe

    A oferta de crédito brasileira : uma análise do período de 2003 a 2010

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    Trabalho de Conclusão de Curso (graduação)—Universidade de Brasília, Departamento de Economia, 2019

    Microestruturas e mecanismos de deformação ao longo da zona de cisalhamento Patos

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    Orientador: Prof. Dr. Leonardo Evangelista LagoeiroCoorientadora: Profa. Dra. Paola Ferreira BarbosaDissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências da Terra, Programa de Pós-Graduação em Geologia. Defesa : Curitiba, 20/12/2021Inclui referênciasResumo: Estudos microestruturais e texturais em milonitos quartzo-feldspáticos são fundamentais para compreender como a deformação é localizada na crosta intermediária. Contudo, estudos de tais naturezas em zonas de cisalhamento brasileiras são escassos. Dentre estas estruturas, se destaca o lineamento Patos, uma zona de cisalhamento com mais de 600 km de extensão de que deformou o embasamento paleoprotoerozóico da Província Borborema sob diferentes condições de temperatura. De modo a compreender os processos no estado sólido responsáveis por localizar e acomodar a deformação ao longo do Lineamento Patos, e o consequentemente enfraquecimento crustal promovido pelo seu desenvolvimento, milonitos quartzo-feldspáticos foram investigados por meio de microscopia óptica, microscópio eletrônico de varredura e principalmente por meio da técnica de difração de elétrons retroespalhados (EBSD). Os resultados obtidos indicam uma deformação extremamente heterogênea, caracterizada pela acomodação da deformação em zonas cada vez mais estreitas conforme a temperatura decresce durante o soerguimento das rochas afetadas pelo lineamento. Em condições de altas temperaturas (>700°C), após uma deformação predominantemente no estado magmático, camadas ricas em biotita tornam-se os domínios reológicos mais fracos, com a deformação sendo principalmente acomodada nestas camadas por meio da fluência de deslocações nos feldspatos, que registram a ativação do sistema (010)[100], e no quartzo, que registra a ativação dos sistemas Prisma- e Prisma-[c]. Sob condições de temperaturas intermediárias (550-480°C), a deformação foi principalmente acomodada pela fluência de deslocações no quartzo e no plagioclásio, e de modo restrito no feldspato potássico. O quartzo apresenta microestruturas que indicam recristalização durante a transição de migração por borda de grão para rotação de subgrão. Os principais sistemas de deslizamento ativos foram (010)[100], (010)[001] e possivelmente (011)[100] no plagioclásio, (010)[100] no feldspato potássico, e prisma- no quartzo. Recristalização do plagioclásio e mimerquitização do feldspato potássico seguido pela sua precipitação ao longo de sombras de pressão promoveram a redução do tamanho dos grãos e a formação de agregados poliminerálicos de granulação fina, que deformaram por meio de deslizamento de borda de grão assistido por fluência de deslocações ou por fluido, com a possível ativação dos sistemas (011)[1-11], (010)[100], (10-1)[111] e (1-1-1)[110], deste modo promovendo mais enfraquecimento nas rochas deformadas. Sob condições de baixas temperaturas ( e romboédrico- de modo subordinado. A expressão desta deformação nos milonitos de media a alta temperatura ao norte da borda sul ocorre na forma de delgadas zonas de cisalhamentos localizadas ao longo de descontinuidades estruturais como contato entre camadas e fraturas transgranulares. Além disso, foi sugerido que os sistemas (100)[010] no feldspato potássico e (021)[1-12] no plagioclásio reportados em trabalhos prévios podem ser fruto de interpretações errôneas.Abstract: Microstructural and textural Studies of quartzo-feldspathic mylonites are essential to understand how the strain is localized and accommodated in the midcrust. However, such studies in Brazilian shear zones are few. One of these structures is the Patos Lineament, a ~600 km long shear zone that deformed the paleoproterozoic basement of Borborema Province under different temperature conditions. In order to comprehend the solid-state processes responsible for strain localization and accommodation in the Patos shear zone, and the consequent crustal weakening promoted by its development, quartzo-feldspathic mylonites were investigated by means of optical microscopy, scanning electron microscopy and electron backscattering diffraction technique (EBSD). The results obtained from this study point out a heterogeneous deformation characterized by the accommodation of deformation in increasingly thinner high strain zones under decreasing temperatures during uplifting. At high-temperature deformation conditions (>700°C), after magmatic-state deformation, biotite-rich layers turn into the rheologically weaker domains which accommodated strain via dislocation creep, with the activation of (010)[100] in feldspar and prism- and prism-[c] in quartz. Under mediumtemperature conditions (550-480°C), deformation was mainly accommodated by dislocation creep in the quartz and plagioclase, and in a restricted way in the Kfeldspar. The quartz display microstructures that indicate recrystallization during the transition from Grain boundary migration to subgrain rotation. The main active slip system were (010)[100], (010)[001] and possibly (011)[100] in the plagioclase, (010)[100] in the K-feldspar, and prism- in the quartz. Recrystallization of plagioclase and myrmekitization of k-feldspar followed by the precipitation by solution in strain shadows promoted grain-size reduction and formation of the fine-grained polymineralic aggregates which deformed by dislocation-accommodated or fluidassisted grain boundary sliding, with the activation of the easy slip systems (011)[1- 11], (010)[100], (10-1)[111] and (1-1-1)[110], thus favouring further strain weakening of rocks. Under low-temperature conditions ( and minor rhomb- slip systems. The low-temperature deformation in the medium- to high-temperature mylonites located at the northern block of the Patos shear zone is expressed by small-scale shear zones localized along structural discontinuities like layer contacts and transgranular fractures. Furthermore, was suggested that the slip systems (100)[010] in K-feldspar and (021)[1-12] in plagioclase reported in previous studies may be products of misinterpretation

    Major cellular and molecular processes and clinical outcomes in bone regeneration for successful dental implantation: a systematic review

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    Introduction: In the context of bone regeneration, bone defects still represent a major challenge in oral and maxillofacial clinical and surgical treatment. The biomimetic design of biomaterials by simulating the natural structure and composition of bone tissue has gradually become a point of research interest due to its advantages of simplicity and efficiency. Objective: It was to carry out a systematic review on cellular and molecular processes, as well as to present the main clinical approaches of bone regeneration for dental implants. Methods: The present study followed a systematic review model, following the rules of systematic review – PRISMA. The search strategy was performed in the PubMed, Cochrane Library, Web of Science and Scopus, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results: A total of 142 articles were found. A total of 84 articles were fully evaluated and 33 were included in this study. Literary findings have shown that the lack of bone in the alveolar ridges has been a major problem in functional aesthetic recovery in patients who have suffered dentoalveolar trauma. The osteoinduction process is influenced by several factors, requiring the presence of inducers, which include β-glycerolphosphate, ascorbic acid, and dexamethasone. Mesenchymal stem cells acquire the morphology and components of osteoblastic membranes and begin to express alkaline phosphatase to deposit extracellular matrix rich in calcium and certain proteins, such as osteopontin and osteocalcin. The Bio Oss® (Geistlich) biomaterial, because it is biodegradable, biocompatible, non-toxic, and has low immunogenicity and bio stimulators, can act in the regeneration of bone tissue. Application of FRP and implant placement provides stable clinical results for severely atrophic maxilla 2-4 mm. Bovine xenograft alone and in combination with liquid FRP are both successful in achieving bone augmentation around implants and produce a small change in marginal bone level and a high implant survival rate after loading. Conclusion: Through the results of the present study, it was evidenced that the success of the dental implant is directly related to successful osseointegration

    Crítica ao planejamento participativo no ensino médio: em defesa do ensino do conhecimento científico na escola pública

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    O presente estudo apresenta como objeto o planejamento participativo. Objetivou analisar a contribuição deste tipo de planejamento para o trato com o conhecimento no que se refere a seleção, organização e sistematização dos conteúdos de ensino na disciplina educação física. A pesquisa foi referenciada no materialismo histórico-dialético e utilizou-se da análise de conteúdo como técnica da análise de dados. Foi realizada no ensino médio da Escola Estadual de Ensino Fundamental e Médio Antônia Rangel de Farias em João Pessoa-PB. Foram utilizados como instrumentos para levantar os dados da realidade: questionários para os alunos e entrevista semi-estruturada para a professora. Como resultado, verificou-se a falta de domínio dos elementos necessários para a atividade de selecionar os conteúdos considerando os princípios curriculares para o trato com o conhecimento da abordagem Crítico-Superadora. Concluímos que o planejamento participativo não contribuiu para o desenvolvimento do trato com o conhecimento da educação física na perspectiva da construção de uma escola que valorize a transmissão do conhecimento objetivo e elaborado

    Análise da abordagem para consumo conspícuo da marca Rolex

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    Orientador: Prof. José Felipe Araujo de AlmeidaTrabalho de Conclusão de Curso (graduação) - Universidade Federal do Paraná, Setor de Ciências Sociais Aplicadas, Curso de Ciências EconômicasInclui referênciasResumo : Este trabalho busca demonstrar de maneira empírica o padrão de consumo de ostentação baseado na vertente institucionalista com foco na teoria da classe ociosa de Thortstain Veblen, a fim de demonstrar o padrão de consumo conspícuo com base na empresa Rolex S/A, e como ocorre este processo observando elementos históricos de como ela conseguiu status de ostentação conspícua de bens. O estudo visa mostrar a perspectiva institucionalista sobre a ideia de estilo de vida atribuído ao luxo, o que contrasta com o preço ao consumidor e a possibilidade de adquirir bens de consumo Rolex, considerando a perspectiva de comportamento individual

    Introduction: Disease reservoirs : from colonial medicine to one health

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    Funding: Wellcome Trust, Canadian Institute for Advance Research, Agence Nationale de la Recherche.The introduction of the special issue “Disease Reservoirs: Anthropological and Historical Approaches” sets out the origins and trajectories of disease reservoir frameworks. First, it charts the emergence and elaborations of the reservoirs concept within and across early 20th-century colonial contexts, emphasising its configuration within imperial projects that sought to identify, map and control spaces of contagion among humans, animals, and pathogens. Following this, it traces the position the reservoir framework assumed within post-colonial practices and imaginaries of global health, with particular reference to the emerging infectious disease paradigm. The introduction shows that, in contemporary usages, while the concept continues to frame animals, humans and their bodies as containers of previously identified pathogens, it also emphasises the imperative of anticipating as-of-yet unknown diseases, harboured in the bodies of certain animals, through networks and techniques of surveillance. Consequently, the introduction argues that the notion of disease reservoirs remains intimately intertwined with concerns over the classification, organization, and management of peoples, pathogens, animals, and space. Finally, the introduction outlines the seven papers that form this special issue, stressing how they dialogue, complement, and challenge previous historical and anthropological approaches to disease reservoirs, with an eye to opening up new avenues for cross-disciplinary exploration.Publisher PDFPeer reviewe

    Estudo Comparativo de Tecnologias de Desenvolvimento front-end paraWeb

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    There are several JavaScript technologies intended to assist in theconstruction of web systems user interfaces. Choose the most suitablefor a new project can be a difficult task. Three of these technologieshave gained prominence: Angular, Vue and React. All focusedon the front-end development of web applications. In order to facilitatethe process of decision making about which technology is themost suitable in a new project, this work establishes a comparativestudy of the three most used JavaScript technologies currently andto highlight the advantages and disadvantages of each one. Thiswork adopted performance, size and support for different browsersto carry out an experimental comparative study. An applicationwas developed as a use case and replicated in each of the technologies,in order to analyze the development process and the resultsunder the same set of tests. A software to perform the tests in anautomated way was implemented to collect the performance resultsusing the Google Chrome browser. It was possible to identify whichtechnology is most suitable in each test scenario. For example, theAngular framework performed better in 8 out of 10 scenarios evaluated,despite having a longer startup time and build size of theapplication compared to React and Vue. It is estimated that Angularloads more information in the initialization process to make thestate of the application “more prepared” for user interaction

    As tecnologias de comunicação usadas para produzir uma educação cientifica-tecnologica

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    Anais do II Seminário Seminário Estadual PIBID do Paraná: tecendo saberes / organizado por Dulcyene Maria Ribeiro e Catarina Costa Fernandes — Foz do Iguaçu: Unioeste; Unila, 2014O trabalho foi desenvolvido e aplicado em um colégio da rede pública através do PIBID-UFPR (Programa Institucional de Bolsa de Iniciação à Docência), este trabalho tem o intuito de incluir “objetos-problemas” ligados à tecnologia no ensino de uma turma de terceira série do ensino médio. Especificamente neste trabalho, o objeto escolhido foi o rádio de galena, tendo como embasamento técnico e didático o material desenvolvido pelo GREF-USP (Grupo de Reelaboração do Ensino de Física). O objetivo central de nosso trabalho é utilizar o rádio mostrar a interação de tecnologia e ciência, fazendo com que o pensamento científico dos estudantes possa ser mais crítico, principalmente frente a questões tecnológicas. O enfoque CTS foi bastante utilizado durante nosso trabalho, estando presente em reflexões acerca da mudança de pensamento diante as tecnologias de informação e comunicaçã
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