Immunological Studies of Bullous Pemphigoid in Relation to Other Bullous Diseases

Bullous pemphigoid is a chronic autoimmune blistering disease of the elderly. The disorder is associated with linear deposition of IgG and complement along the epidermal basement membrane. Circulating IgG autoantibodies are present in the majority of patients and bind to a normal component of the basement membrane zone, the bullous pemphigoid antigen