698 research outputs found
A validated integrated clinical and molecular glioblastoma long-term survival-predictive nomogram.
- Author
- Publication venue
- The Mouseion at the JAXlibrary
- Publication date
- 01/01/2021
- Field of study
Get PDFBackground: Glioblastoma (GBM) is the most common primary malignant brain tumor in adulthood. Despite multimodality treatments, including maximal safe resection followed by irradiation and chemotherapy, the median overall survival times range from 14 to 16 months. However, a small subset of GBM patients live beyond 5 years and are thus considered long-term survivors.
Methods: A retrospective analysis of the clinical, radiographic, and molecular features of patients with newly diagnosed primary GBM who underwent treatment at The University of Texas MD Anderson Cancer Center was conducted. Eighty patients had sufficient quantity and quality of tissue available for next-generation sequencing and immunohistochemical analysis. Factors associated with survival time were identified using proportional odds ordinal regression. We constructed a survival-predictive nomogram using a forward stepwise model that we subsequently validated using The Cancer Genome Atlas.
Results: Univariate analysis revealed 3 pivotal genetic alterations associated with GBM survival: both high tumor mutational burden (
Conclusions: Our newly devised long-term surviva
ϒ production in p–Pb collisions at √sNN=8.16 TeV
- Author
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- Yokoyama H.
- Yoo I.-K.
- Yoon J.H.
- Yuan S.
- Yuncu A.
- Yurchenko V.
- Zaccolo V.
- Zaman A.
- Zampolli C.
- Zanoli H.J.C.
- Zardoshti N.
- Zarochentsev A.
- Zaviyalov N.
- Zbroszczyk H.
- Zhalov M.
- Zhang S.
- Zhang X.
- Zhang Z.
- Zherebchevskii V.
- Zhou D.
- Zhou Y.
- Zhou Z.
- Zhu J.
- Zhu Y.
- Zichichi A.
- Zimmermann Markus
- Zinovjev Gennady M.
- Zurlo Nicola
- Závada P.
- Šafařík K.
- Šefčík M.
- Šumbera M.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study
Get PDFϒ production in p–Pb interactions is studied at the centre-of-mass energy per nucleon–nucleon collision √sNN = 8.16 TeV with the ALICE detector at the CERN LHC. The measurement is performed reconstructing bottomonium resonances via their dimuon decay channel, in the centre-of-mass rapidity intervals 2.03 < ycms < 3.53 and −4.46 < ycms < −2.96, down to zero transverse momentum. In this work, results on the ϒ(1S) production cross section as a function of rapidity and transverse momentum are presented. The corresponding nuclear modification factor shows a suppression of the ϒ(1S) yields with respect to pp collisions, both at forward and backward rapidity. This suppression is stronger in the low transverse momentum region and shows no significant dependence on the centrality of the interactions. Furthermore, the ϒ(2S) nuclear modification factor is evaluated, suggesting a suppression similar to that of the ϒ(1S). A first measurement of the ϒ(3S) has also been performed. Finally, results are compared with previous ALICE measurements in p–Pb collisions at √sNN = 5.02 TeV and with theoretical calculations.publishedVersio
Azimuthal anisotropy of charged jet production in root s(NN)=2.76 TeV Pb-Pb collisions
- Author
- Adam Jaroslav
- Adamova Dagmar
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aiola Salvatore
- Akindinov Alexander
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alexandre Didier
- Alfaro Molina Jose Ruben
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altinpinar Sedat
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andronic Anton
- Anguelov Venelin
- Anielski Jonas
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Arnaldi Roberta
- Arnold Oliver Werner
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Badala Angela
- Baek Yong Wook
- Bagnasco Stefano
- Bailhache Raphaelle Marie
- Bala Renu
- Baldisseri Alberto
- Baral Rama Chandra
- Barbano Anastasia Maria
- Barbera Roberto
- Barile Francesco
- Barnafoldi Gergely Gabor
- Barnby Lee Stuart
- Bartalini Paolo
- Barth Klaus
- Bartke Jerzy Gustaw
- Bartsch Esther
- Bashir Butt Jamila
- Basile Maurizio
- Bastid Nicole
- Basu Sumit
- Bathen Bastian
- Batigne Guillaume
- Batista Camejo Arianna
- Batyunya Boris
- Batzing Paul Christoph
- Bearden Ian Gardner
- Beck Hans
- Bedda Cristina
- Behera Nirbhay Kumar
- Belikov Iouri
- Bellini Francesca
- Bello Martinez Hector
- Bellwied Rene
- Belmont Iii Ronald John
- Belmont Moreno Ernesto
- Belyaev Vladimir
- Bencedi Gyula
- Beole Stefania
- Berceanu Ionela
- Bercuci Alexandru
- Berdnikov Yaroslav
- Berenyi Daniel
- Bertens Redmer Alexander
- Berzano Dario
- Betev Latchezar
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- Bhattacharjee Buddhadeb
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- Bilandzic Ante
- Biswas Rathijit
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- Blume Christoph
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- Boettger Stefan
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- Buthelezi Edith Zinhle
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- Caines Helen Louise
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- Caliva Alberto
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- Camerini Paolo
- Carena Francesco
- Carena Wisla
- Carnesecchi Francesca
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- Castro Andrew John
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- Ceballos Sanchez Cesar
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- Cerkala Jakub
- Chang Beomsu
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- Cherney Michael Gerard
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- Cho Soyeon
- Chochula Peter
- Choi Kyungeon
- Chojnacki Marek
- Choudhury Subikash
- Christakoglou Panagiotis
- Christensen Christian Holm
- Christiansen Peter
- Chujo Tatsuya
- Chung Suh-Urk
- Chunhui Zhang
- Cicalo Corrado
- Cifarelli Luisa
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- Viesti Giuseppe
- Viinikainen Jussi Samuli
- Vilakazi Zabulon
- Villalobos Baillie Orlando
- Villatoro Tello Abraham
- Vinogradov Alexander
- Vinogradov Leonid
- Vinogradov Yury
- Virgili Tiziano
- Vislavicius Vytautas
- Viyogi Yogendra
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- Vorobyev Ivan
- Vranic Danilo
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- Vulpescu Bogdan
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- Wagner Jan
- Wang Hongkai
- Wang Mengliang
- Watanabe Daisuke
- Watanabe Yosuke
- Weber Michael
- Weber Steffen Georg
- Weiser Dennis Franz
- Wessels Johannes Peter
- Westerhoff Uwe
- Whitehead Andile Mothegi
- Wiechula Jens
- Wikne Jon
- Wilde Martin Rudolf
- Wilk Grzegorz Andrzej
- Wilkinson Jeremy John
- Williams Crispin
- Windelband Bernd Stefan
- Winn Michael Andreas
- Yaldo Chris G
- Yang Hongyan
- Yang Ping
- Yano Satoshi
- Yasar Cigdem
- Yin Zhongbao
- Yokoyama Hiroki
- Yoo In-Kwon
- Yoon Jin Hee
- Yurchenko Volodymyr
- Yushmanov Igor
- Zaborowska Anna
- Zaccolo Valentina
- Zaman Ali
- Zampolli Chiara
- Zaporozhets Sergey
- Zardoshti Nima
- Zarochentsev Andrey
- Zavada Petr
- Zavyalov Nikolay
- Zbroszczyk Hanna Paulina
- Zgura Sorin Ion
- Zhalov Mikhail
- Zhang Haitao
- Zhang Xiaoming
- Zhang Yonghong
- Zhang Zuman
- Zhao Chengxin
- Zhigareva Natalia
- Zhou Daicui
- Zhou You
- Zhou Zhuo
- Zhu Hongsheng
- Zhu Jianhui
- Zichichi Antonino
- Zimmermann Alice
- Zimmermann Markus Bernhard
- Zinovjev Gennady
- Zyzak Maksym
- Publication venue
- Publication date
- 14/09/2015
- Field of study
Get PDFWe present measurements of the azimuthal dependence of charged jet production in central and semi-central root s(NN) = 2.76 TeV Pb-Pb collisions with respect to the second harmonic event plane, quantified as nu(ch)(2) (jet). Jet finding is performed employing the anti-k(T) algorithm with a resolution parameter R = 0.2 using charged tracks from the ALICE tracking system. The contribution of the azimuthal anisotropy of the underlying event is taken into account event-by-event. The remaining (statistical) region-to-region fluctuations are removed on an ensemble basis by unfolding the jet spectra for different event plane orientations independently. Significant non-zero nu(ch)(2) (jet) is observed in semi-central collisions (30-50% centrality) for 20 <p(T)(ch) (jet) <90 GeV/c. The azimuthal dependence of the charged jet production is similar to the dependence observed for jets comprising both charged and neutral fragments, and compatible with measurements of the nu(2) of single charged particles at high p(T). Good agreement between the data and predictions from JEWEL, an event generator simulating parton shower evolution in the presence of a dense QCD medium, is found in semi-central collisions. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe
Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC
- Author
- Acharya Shreyasi
- Adamova Dagmar
- Adolfsson Jonatan
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aiola Salvatore
- Akindinov Alexander
- Al-turany Mohammad
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alfaro Molina Jose Ruben
- Ali Yasir
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altenkamper Lucas
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andreou Dimitra
- Andrews Harry Arthur
- Andronic Anton
- Anguelov Venelin
- Anson Christopher Daniel
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Arnaldi Roberta
- Arnold Oliver Werner
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Badala Angela
- Baek Yong Wook
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- Zaccolo Valentina
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- Zhalov Mikhail
- Zhang Haitao
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- Zhang Yonghong
- Zhang Zuman
- Zhao Chengxin
- Zhigareva Natalia
- Zhou Daicui
- Zhou You
- Zhou Zhuo
- Zhu Hongsheng
- Zhu Jianhui
- Zhu Ya
- Zichichi Antonino
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- Zmeskal Johann
- Zou Shuguang
- Publication venue
- Publication date
- 01/01/2017
- Field of study
Get PDFResults on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe
Forward-central two-particle correlations in p-Pb collisions at root s(NN)=5.02 TeV
- Author
- Adam Jaroslav
- Adamova Dagmar
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aimo Ilaria
- Aiola Salvatore
- Ajaz Muhammad
- Akindinov Alexander
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alexandre Didier
- Alfaro Molina Jose Ruben
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altinpinar Sedat
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andronic Anton
- Anguelov Venelin
- Anielski Jonas
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Armesto Perez Nestor
- Arnaldi Roberta
- Arsene Ionut Cristian
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- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Bach Matthias Jakob
- Badala Angela
- Baek Yong Wook
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- Bailhache Raphaelle Marie
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- Wilde Martin Rudolf
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- Yaldo Chris G
- Yang Hongyan
- Yang Ping
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- Yin Zhongbao
- Yokoyama Hiroki
- Yoo In-Kwon
- Yurchenko Volodymyr
- Yushmanov Igor
- Zaborowska Anna
- Zaccolo Valentina
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- Zardoshti Nima
- Zarochentsev Andrey
- Zavada Petr
- Zavyalov Nikolay
- Zbroszczyk Hanna Paulina
- Zgura Sorin Ion
- Zhalov Mikhail
- Zhang Chunhui
- Zhang Haitao
- Zhang Xiaoming
- Zhang Yonghong
- Zhao Chengxin
- Zhigareva Natalia
- Zhou Daicui
- Zhou You
- Zhou Zhuo
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- Publication venue
- Publication date
- 26/06/2015
- Field of study
Get PDFTwo-particle angular correlations between trigger particles in the forward pseudorapidity range (2.5 2GeV/c. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B. V.Peer reviewe
Event-shape engineering for inclusive spectra and elliptic flow in Pb-Pb collisions at root(NN)-N-S=2.76 TeV
- Author
- Adam Jaroslav
- Adamova Dagmar
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aimo Ilaria
- Aiola Salvatore
- Ajaz Muhammad
- Akindinov Alexander
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alexandre Didier
- Alfaro Molina Jose Ruben
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altinpinar Sedat
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andronic Anton
- Anguelov Venelin
- Anielski Jonas
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Armesto Perez Nestor
- Arnaldi Roberta
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Bach Matthias Jakob
- Badala Angela
- Baek Yong Wook
- Bagnasco Stefano
- Bailhache Raphaelle Marie
- Bala Renu
- Baldisseri Alberto
- Baltasar Dos Santos Pedrosa Fernando
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- Barnby Lee Stuart
- Bartalini Paolo
- Barth Klaus
- Bartke Jerzy Gustaw
- Bartsch Esther
- Bashir Butt Jamila
- Basile Maurizio
- Bastid Nicole
- Basu Sumit
- Bathen Bastian
- Batigne Guillaume
- Batista Camejo Arianna
- Batyunya Boris
- Batzing Paul Christoph
- Bearden Ian Gardner
- Beck Hans
- Bedda Cristina
- Behera Nirbhay Kumar
- Belikov Iouri
- Bellini Francesca
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- Bellwied Rene
- Belmont Iii Ronald John
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- Bencedi Gyula
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- 22/07/2015
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Pseudorapidity and transverse-momentum distributions of charged particles in proton-proton collisions at root s=13 TeV
- Author
- Adam Jaroslav
- Adamova Dagmar
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aiola Salvatore
- Akindinov Alexander
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alexandre Didier
- Alfaro Molina Jose Ruben
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altinpinar Sedat
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andronic Anton
- Anguelov Venelin
- Anielski Jonas
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Arnaldi Roberta
- Arnold Oliver Werner
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Badala Angela
- Baek Yong Wook
- Bagnasco Stefano
- Bailhache Raphaelle Marie
- Bala Renu
- Balasubramanian Supraja
- Baldisseri Alberto
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- Yang Ping
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- Yin Zhongbao
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- Yoo In-Kwon
- Yoon Jin Hee
- Yurchenko Volodymyr
- Yushmanov Igor
- Zaborowska Anna
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- Zbroszczyk Hanna Paulina
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- Zhalov Mikhail
- Zhang Haitao
- Zhang Xiaoming
- Zhang Yonghong
- Zhang Zuman
- Zhao Chengxin
- Zhigareva Natalia
- Zhou Daicui
- Zhou You
- Zhou Zhuo
- Zhu Hongsheng
- Zhu Jianhui
- Zichichi Antonino
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- Zimmermann Markus Bernhard
- Zinovjev Gennady
- Zyzak Maksym
- Publication venue
- Publication date
- 29/09/2015
- Field of study
Get PDFThe pseudorapidity (eta) and transverse-momentum (p(T)) distributions of charged particles produced in proton-proton collisions are measured at the centre-of-mass energy root s = 13 TeV. The pseudorapidity distribution in vertical bar eta vertical bar <1.8 is reported for inelastic events and for events with at least one charged particle in vertical bar eta vertical bar <1. The pseudorapidity density of charged particles produced in the pseudorapidity region vertical bar eta vertical bar <0.5 is 5.31 +/- 0.18 and 6.46 +/- 0.19 for the two event classes, respectively. The transverse-momentum distribution of charged particles is measured in the range 0.15 <p(T) <20 GeV/c and vertical bar eta vertical bar <0.8 for events with at least one charged particle in vertical bar eta vertical bar <1. The evolution of the transverse momentum spectra of charged particles is also investigated as a function of event multiplicity. The results are compared with calculations from PYTHIA and EPOS Monte Carlo generators. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe
Elliptic flow of muons from heavy-flavour hadron decays at forward rapidity in Pb-Pb collisions at root s(NN)=2.76TeV
- Author
- Adam Jaroslav
- Adamova Dagmar
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aiola Salvatore
- Akindinov Alexander
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alexandre Didier
- Alfaro Molina Jose Ruben
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altinpinar Sedat
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andronic Anton
- Anguelov Venelin
- Anielski Jonas
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Armesto Perez Nestor
- Arnaldi Roberta
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Bach Matthias Jakob
- Badala Angela
- Baek Yong Wook
- Bagnasco Stefano
- Bailhache Raphaelle Marie
- Bala Renu
- Baldisseri Alberto
- Baltasar Dos Santos Pedrosa Fernando
- Baral Rama Chandra
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- Batzing Paul Christoph
- Bearden Ian Gardner
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- Vorobyev Ivan
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- Vulpescu Bogdan
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- Watanabe Yosuke
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- Wilde Martin Rudolf
- Wilk Grzegorz Andrzej
- Wilkinson Jeremy John
- Williams Crispin
- Windelband Bernd Stefan
- Winn Michael Andreas
- Yaldo Chris G
- Yang Hongyan
- Yang Ping
- Yano Satoshi
- Yin Zhongbao
- Yokoyama Hiroki
- Yoo In-Kwon
- Yurchenko Volodymyr
- Yushmanov Igor
- Zaborowska Anna
- Zaccolo Valentina
- Zaman Ali
- Zampolli Chiara
- Zaporozhets Sergey
- Zardoshti Nima
- Zarochentsev Andrey
- Zavada Petr
- Zavyalov Nikolay
- Zbroszczyk Hanna Paulina
- Zgura Sorin Ion
- Zhalov Mikhail
- Zhang Chunhui
- Zhang Haitao
- Zhang Xiaoming
- Zhang Yonghong
- Zhang Zuman
- Zhao Chengxin
- Zhigareva Natalia
- Zhou Daicui
- Zhou You
- Zhou Zhuo
- Zhu Hongsheng
- Zhu Jianhui
- Zichichi Antonino
- Zimmermann Alice
- Zimmermann Markus Bernhard
- Zinovjev Gennady
- Zyzak Maksym
- Publication venue
- Publication date
- 11/07/2015
- Field of study
Get PDFThe elliptic flow, v(2), of muons from heavy-flavour hadron decays at forward rapidity (2.5 <y <4) is measured in Pb-Pb collisions at root s(NN)= 2.76TeVwith the ALICE detector at the LHC. The scalar product, two- and four-particle Q cumulants and Lee-Yang zeros methods are used. The dependence of the v(2) of muons from heavy-flavour hadron decays on the collision centrality, in the range 0-40%, and on transverse momentum, p(T), is studied in the interval 3 <p(T)<10 GeV/c. A positive v(2) is observed with the scalar product and two-particle Q cumulants in semi-central collisions (10-20% and 20-40% centrality classes) for the p(T) interval from 3 to about 5GeV/c with a significance larger than 3 sigma, based on the combination of statistical and systematic uncertainties. The v(2) magnitude tends to decrease towards more central collisions and with increasing pT. It becomes compatible with zero in the interval 6 <p(T)<10 GeV/c. The results are compared to models describing the interaction of heavy quarks and open heavy-flavour hadrons with the high-density medium formed in high-energy heavy-ion collisions. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V.Peer reviewe
Underlying Event measurements in pp collisions at s=0.9 and 7 TeV with the ALICE experiment at the LHC
- Author
- A Buckley
- A Capella
- A. Kurepin
- A.B. Kurepin
- A.K. Dutta Majumdar
- Abdiel Ramirez Reyes
- Adam Ryszard Kisiel
- Adam Tomasz Matyja
- Adam Wlodzimierz Jacholkowski
- Aditya Nath Mishra
- Adrian Sevcenco
- Adriana Telesca
- Airton Deppman
- Ajay Kumar Dash
- Ajit Kumar Mohanty
- AK Aamodt
- Alain Baldit
- Alain Michalon
- Alberica Toia
- Alberto Baldisseri
- Alberto Gago
- Alberto Masoni
- Alberto Pulvirenti
- Alejandro Szanto de Toledo
- Alessandra Fantoni
- Alessandra Maria Mazzoni
- Alessandro De Falco
- Alessandro Ferretti
- Alessandro Grelli
- Alessandro Pesci
- Alexander Akindinov
- Alexander Borissov
- Alexander Hansen
- Alexander Kluge
- Alexander Mamonov
- Alexander Nedosekin
- Alexander Ochirov
- Alexander Philipp Kalweit
- Alexander Vinogradov
- Alexander Vodopianov
- Alexander Wilk
- Alexandr Tumkin
- Alexandre Alarcon do Passo Suaide
- Alexandre Nyanin
- Alexandre Rachevski
- Alexandre Shabetai
- Alexandru Bercuci
- Alexandru Florin Dobrin
- Alexei Kaidalov
- Alexei Khanzadeev
- Alexei Pavlinov
- Alexey Bogdanov
- Alexey Kuryakin
- Alexey Vyushin
- Alexis Jean-Michel Mas
- Alfredo Musso
- Alice Zimmermann
- Alina Gabriela Grigoras
- Alla Maevskaya
- Alphonse Rademakers
- Amalia Pop
- Amaya Ofelia Casanova Diaz
- Ana Maria Marin
- Anand Kumar Dubey
- Anatoly Fedunov
- Anatoly Kolojvari
- Anders Nils Erik Oskarsson
- Andras Gabor Agocs
- Andre Augustinus
- Andre Mischke
- Andrea Agostinelli
- Andrea Alici
- Andrea Dainese
- Andrea Danu
- Andrea De Azevedo Moregula
- Andrea Rossi
- Andreas Arend
- Andreas Morsch
- Andrei George Gheata
- Andrei Ionut Herghelegiu
- Andres Sandoval
- Andrew Marshall Adare
- Andrey Ivanov
- Andrey Kazantsev
- Andrey Korneev
- Andrey Reshetin
- Andrey Vasiliev
- Andrey Zarochentsev
- Andry Malala Rakotozafindrabe
- Andrzej Deloff
- Andrzej Rybicki
- Andzhey Asryan
- Angela Badala
- Anik Gupta
- Anitha Nyatha
- Anju Bhasin
- Ankita Goswami
- Anna Piccotti
- Anna Rita Reolon
- Annalisa De Caro
- Annalisa Mastroserio
- Annika Passfeld
- Anselmo Margotti
- Ante Bilandzic
- Anthony Timmins
- Antoine Xavier Lardeux
- Anton Alkin
- Anton Andronic
- Anton Jusko
- Antonin Maire
- Antonino Zichichi
- Antonio Di Mauro
- Antonio Juan Rubio Montero
- Antonio Ortiz Velasquez
- Antonio Uras
- Ara Grigoryan
- Arian Abrahantes Quintana
- Armando Palmeri
- Arnulfo Martinez Davalos
- Arsen Hayrapetyan
- Arshad Ahmad
- Artem Konevskih
- Artur Krzysztof Szostak
- Arturo Alejandro Menchaca-Rocha
- Arturo Fernandez Tellez
- Arturo Tauro
- Arvinder Singh Palaha
- Ashok Kumar Bhati
- Aurora Diozcora Vargas
- Ayben Karasu Uysal
- B Andersson
- Baba Potukuchi
- Barbara Guerzoni
- Barthelemy von Haller
- Basanta Kumar Nandi
- Bastian Bathen
- Bedangadas Mohanty
- Benjamin Donigus
- Beomkyu Kim
- Beomsu Chang
- Bernard Hicks
- Bernd Stefan Windelband
- Bernhard Skaali
- Betty Abelev
- Bikash Sinha
- Bjarte Kileng
- Bjorn Steven Nilsen
- Blahoslav Pastircak
- Bogdan Theodor Rascanu
- Bogdan Vulpescu
- Borge Svane Nielsen
- Boris Batyunya
- Boris Grinyov
- Boris Hippolyte
- Boris Polichtchouk
- Boris Wagner
- Branislav Sitar
- Brigitte Cheynis
- Brijesh Kumar Srivastava
- Bruno Alessandro
- Bruno Alexandre Boyer
- Bruno Espagnon
- Bruno Ghidini
- Byounghee Han
- Camilo Andres Carrillo Montoya
- Camilo Ernesto Lara
- Carlos Albert Salgado
- Carlos Eugenio Perez Lara
- Carlos Pajares
- Carmelo Di Giglio
- Carsten Sogaard
- Casper Nygaard
- Catia Petta
- Cenek Zach
- Cesar Guerra Gutierrez
- Chamath Kottachchi Kankanamge Don
- Chiara Bianchin
- Chiara Oppedisano
- Chiara Zampolli
- Christelle Sophie Roy
- Christian Claude Kuhn
- Christian Holm Christensen
- Christian Joachim Schmidt
- Christian Klein-Bosing
- Christian Lippmann
- Christina Markert
- Christine Nattrass
- Christoph Blume
- Christoph Heinrich Baumann
- Christoph Mayer
- Christophe Furget
- Christophe Pierre Suire
- Christopher Daniel Anson
- Christos Tagridis
- Cinzia Luzzi
- Ciprian Mihai Mitu
- Claude Andre Pruneau
- Claudio Bortolin
- Claudio Geuna
- Claudiu Cornel Schiaua
- Constantinos Loizides
- Corrado Cicalo
- Costanza Cavicchioli
- Costin Grigoras
- Crispin Williams
- Cristian Andrei
- Cristian George Ivan
- Cristina Lazzeroni
- Cristina Terrevoli
- Csaba Soos
- Cvetan Cheshkov
- Cynthia Marie Hadjidakis
- Cyrano Bergmann
- D Acosta
- Dae Sung Hwang
- Dagmar Adamova
- Daicui Zhou
- Daniel Berenyi
- Daniel Felea
- Daniel Jesus Tapia Takaki
- Daniel Lohner
- Daniel Mayani
- Daniela Fabris
- Daniele De Gruttola
- Danilo Vranic
- Danthasinghe Piyarathna
- Dario Berzano
- Dariusz Miskowiec
- David Chinellato
- David Christopher Truesdale
- David Evans
- David Olle Rickard Silvermyr
- David Philip Emschermann
- David Rohr
- David Tlusty
- Davide Caffarri
- Davide Falchieri
- Davide Perrino
- Debasish Das
- Deepa Thomas
- Deepika Rathee
- Denise Aparecida Moreira De Godoy
- Despoina Hatzifotiadou
- Dhevan Raja Gangadharan
- Diego Perini
- Diego Stocco
- Dieter Rohrich
- Dilan Minthaka Madagodahettige-Don
- Dmitri Ivanovich Patalakha
- Dmitri Peresunko
- Dmitry Aleksandrov
- Dmitry Blau
- Dmitry Budnikov
- Dmitry Finogeev
- Dmitry Mal’Kevich
- Do Won Kim
- Domenico Colella
- Domenico Di Bari
- Domenico Elia
- Dominik Fehlker
- Don Constantin Vernekohl
- Dong Jo Kim
- Dong Wang
- Dosatsu Sakata
- Dumitru Hasegan
- Durga Prasad Mahapatra
- Edgar Perez Lezama
- Edith Zinhle Buthelezi
- Edmundo Garcia-Solis
- Eduardo Del Castillo Sanchez
- Eleazar Cuautle
- Elena Bruna
- Elena Gonzalez Ferreiro
- Elienos Pereira De Oliveira Filho
- Elisa Incani
- Elisabetta Crescio
- Emanuele Quercigh
- Emilia Cruz Alaniz
- Emilio Chiavassa
- Enrichetta Maria Fiore
- Enrico Fragiacomo
- Enrico Scomparin
- Erick Jonathan Almaraz Avina
- Ermanno Vercellin
- Ernesto Belmont-Moreno
- Ernesto Calvo Villar
- Ernesto Lopez Torres
- Ervin Denes
- Ester Anna Rita Casula
- Esther Montes
- Eugen Mudnic
- Eugenio Nappi
- Eugenio Scapparone
- Eulogio Serradilla
- Eva Sicking
- Evert Anders Stenlund
- Evgeny Karpechev
- Evgeny Kryshen
- Evgeny Ryabinkin
- Ewa Gladysz-Dziadus
- F. Blanco
- Fabio Colamaria
- Fabrizio Coccetti
- Fatima Padilla
- Federico Antinori
- Federico Carminati
- Federico Cindolo
- Federico Ronchetti
- Fedor Guber
- Felix Vincenz Rettig
- Fengchu Zhou
- Fernando Baltasar Dos Santos Pedrosa
- Fernando Scarlassara
- Filimon Roukoutakis
- Filip Krizek
- Filippo Costa
- Fiorella Fionda
- Flavio Tosello
- Florian Painke
- Francesca Bellini
- Francesca Soramel
- Francesco Barile
- Francesco Blanco
- Francesco Bossu
- Francesco Carena
- Francesco Noferini
- Francesco Prino
- Francesco Riggi
- Franck Manso
- Franco Meddi
- Francois Piuz
- Frederic Lefevre
- Frederick Kramer
- G Aad
- G Aad
- Gabriel de Barros
- Galina Shabratova
- Gaute vrebekk
- Gennady Zinovjev
- Gerardo Antonio Herrera Corral
- Gerardus Nooren
- Gergely Gabor Barnafoldi
- Gergoe Hamar
- Giacinto de Cataldo
- Giacomo Contin
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- Gines Martinez Garcia
- Ginevra D’Erasmo
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- Giovanna Puddu
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- Giuseppe Eugenio Bruno
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- Ingvar Otterlund
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- Iouri Belikov
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- Iryna Ilkiv
- Isabel Dominguez
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- Janka Vrlakova
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- Jean-Sebastien Real
- Jean-Yves Grossiord
- Jeewon Seo
- Jennifer Lynn Klay
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- Jens Wiechula
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- Jesus Guillermo Contreras
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Full text linkA validated integrated clinical and molecular glioblastoma long-term survival-predictive nomogram
- Author
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2021
- Field of study
Full text linkBackgroundGlioblastoma (GBM) is the most common primary malignant brain tumor in adulthood. Despite multimodality treatments, including maximal safe resection followed by irradiation and chemotherapy, the median overall survival times range from 14 to 16 months. However, a small subset of GBM patients live beyond 5 years and are thus considered long-term survivors.MethodsA retrospective analysis of the clinical, radiographic, and molecular features of patients with newly diagnosed primary GBM who underwent treatment at The University of Texas MD Anderson Cancer Center was conducted. Eighty patients had sufficient quantity and quality of tissue available for next-generation sequencing and immunohistochemical analysis. Factors associated with survival time were identified using proportional odds ordinal regression. We constructed a survival-predictive nomogram using a forward stepwise model that we subsequently validated using The Cancer Genome Atlas.ResultsUnivariate analysis revealed 3 pivotal genetic alterations associated with GBM survival: both high tumor mutational burden (P = .0055) and PTEN mutations (P = .0235) negatively impacted survival, whereas IDH1 mutations positively impacted survival (P < .0001). Clinical factors significantly associated with GBM survival included age (P < .0001), preoperative Karnofsky Performance Scale score (P = .0001), sex (P = .0164), and clinical trial participation (P < .0001). Higher preoperative T1-enhancing volume (P = .0497) was associated with shorter survival. The ratio of TI-enhancing to nonenhancing disease (T1/T2 ratio) also significantly impacted survival (P = .0022).ConclusionsOur newly devised long-term survival-predictive nomogram based on clinical and genomic data can be used to advise patients regarding their potential outcomes and account for confounding factors in nonrandomized clinical trials
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